scholarly journals Murine abdominal aortic aneurysm model by orthotopic allograft transplantation of elastase-treated abdominal aorta

2015 ◽  
Vol 62 (6) ◽  
pp. 1607-1614.e2 ◽  
Author(s):  
Zhenjie Liu ◽  
Qiwei Wang ◽  
Jun Ren ◽  
Carmel Rebecca Assa ◽  
Stephanie Morgan ◽  
...  
2019 ◽  
Vol 13 (9) ◽  
pp. 430-434
Author(s):  
Ian Peate

This is the second article in a series of articles regarding screening programmes. In this article, an overview of the abdominal aorta is provided. The article also considers the abdominal aortic aneurysm screening programme. Aortic abdominal aneurysm is described. The majority of abdominal aortic aneurysms are asymptomatic; however, if there are any symptoms, these are explained. All four UK countries offer men aged 65 years and over a screening opportunity using an ultrasound scan, the fundamental aspects of abdominal aortic aneurysm screening programmes is offered. It is emphasised that screening is not mandatory in the UK; the man has a right to decline the invitation to attend any screening programme.


Author(s):  
Florentina Ene ◽  
Carine Gachon ◽  
Patrick Delassus ◽  
Liam Morris

Abdominal aortic aneurysm (AAA) represents an abnormal dilatation and weakening of the abdominal aorta with high risk of rupture. Most aneurysms of the infrarenal aorta possess an asymmetrical fusiform morphology.


2019 ◽  
Vol 69 (6) ◽  
pp. e94-e95
Author(s):  
Vivian C. Gomes ◽  
Madhavan L. Raghavan ◽  
Luiz F. da Silva ◽  
Selene Zyngier ◽  
Gina Silvestre ◽  
...  

2019 ◽  
Vol 42 (11) ◽  
pp. 1627-1634 ◽  
Author(s):  
Jussi M. Kärkkäinen ◽  
Giuliano Sandri ◽  
Emanuel R. Tenorio ◽  
Amy Alexander ◽  
Karen Bjellum ◽  
...  

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Yuko Ishida ◽  
Yumi Kuninaka ◽  
Mizuho Nosaka ◽  
Akihiko Kimura ◽  
Akira Taruya ◽  
...  

AbstractInflammatory mediators such as cytokines and chemokines are crucially involved in the development of abdominal aortic aneurysm (AAA). Here we report that CaCl2 application into abdominal aorta induces AAA with intra-aortic infiltration of macrophages as well as enhanced expression of chemokine (C-C motif) ligand 3 (CCL3) and MMP-9. Moreover, infiltrating macrophages express C-C chemokine receptor 5 (CCR5, a specific receptor for CCL3) and MMP-9. Both Ccl3−/− mice and Ccr5−/− but not Ccr1−/− mice exhibit exaggerated CaCl2-inducced AAA with augmented macrophage infiltration and MMP-9 expression. Similar observations are also obtained on an angiotensin II-induced AAA model. Immunoneutralization of CCL3 mimics the phenotypes observed in CaCl2-treated Ccl3−/− mice. On the contrary, CCL3 treatment attenuates CaCl2-induced AAA in both wild-type and Ccl3−/− mice. Consistently, we find that the CCL3–CCR5 axis suppresses PMA-induced enhancement of MMP-9 expression in macrophages. Thus, CCL3 can be effective to prevent the development of CaCl2-induced AAA by suppressing MMP-9 expression.


2019 ◽  
Vol 7 ◽  
pp. 232470961986557
Author(s):  
Asim Kichloo ◽  
M. Zatmar Khan ◽  
El-Amir Zain ◽  
Navya Sree Vipparla ◽  
Farah Wani

Abdominal aortic aneurysm (AAA) is one of the important pathologies involving the abdominal aorta, as it can have adverse consequences if it goes unnoticed or untreated. AAA is defined as an abnormal dilation of the abdominal aorta 3 cm or greater. Endovascular abdominal aortic aneurysm repair (EVAR) has recently emerged as a treatment modality for AAA. It does have a few inherent complications that include endoleak, endograft migration, bleeding, ischemia, and compartment syndrome. This case report discusses a patient who came in with abdominal pain and a pulsatile mass, which raised concerns regarding endoleak. The patient had a 9.9-cm AAA, which was repaired in the past, as was made evident by computed tomography findings of the stent graft in the aneurysmal segment. This case stands out because it highlights the importance of comparing the size of the AAA at the time of the EVAR to the current scenario where the patient presents with abdominal pain of unknown etiology. Also, this case report highlights the importance of computed tomography and other imaging forms in following-up with patients who have EVAR for AAAs.


1903 ◽  
Vol 3 (5-6) ◽  
pp. 289-289
Author(s):  
M. Yu. Gurevich

Abstracts. Surgery."Surgery" v. XIII. No. 73.M. Yu. Gurevich. About the recognition and treatment of abdominal aortic aneurysm. "Russian Doctor". 1903, No. 7.An aneurysm of the abdominal aorta can not easily simulate a neoplasm of any abdominal organ. Since aneurysm is most often formed in the region of the superior mesenteric artery, the organs, the defeat of which must be excluded, include those lying near this place.


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