scholarly journals Granulomatous vasculitis after the Astra-Zeneca anti-SARS-CoV-2 vaccine.

Author(s):  
Valentine Gillion ◽  
Michel Jadoul ◽  
Nathalie Demoulin ◽  
Selda Aydin ◽  
Arnaud Devresse
2021 ◽  
Vol 18 (11) ◽  
pp. 1907-1911
Author(s):  
Felipe de J. Contreras-Rodríguez ◽  
Marco A. Alba ◽  
Rosa M. Rivera-Rosales ◽  
Luis F. Flores-Suárez

2010 ◽  
Vol 134 (4) ◽  
pp. 625-629
Author(s):  
Sarah L. Ondrejka ◽  
Gary W. Procop ◽  
Keith K. Lai ◽  
Richard A. Prayson

Abstract Infection with the saprophagous nematode Halicephalobus species is uncommon but has been reported in horses worldwide. Only 3 human cases have been previously described, all of which have been fatal. We report a fourth fatal case, which occurred in a 39-year-old woman who presented with meningeal signs, altered mental status, and a prodromal pruritic rash. Diagnostic evaluation included an open brain biopsy, which was diagnosed as granulomatous vasculitis. The patient subsequently died after a course of steroids and cyclophosphamide. At autopsy, a robust perivascular mixed inflammatory infiltration of the brain parenchyma, meninges, and ventricular system was present with larval forms and mature nematodes morphologically consistent with Halicephalobus deletrix. Although extremely rare, this organism needs to be considered in the differential diagnosis of human helminthic infection of the central nervous system.


2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
Manpreet K. Parmar ◽  
Mariam Alikhan ◽  
Vivien M. Hsu ◽  
Amanda Borham

Granulomatosis with polyangiitis (GPA) is a rare ANCA-associated necrotizing granulomatous vasculitis affecting small- to medium-sized vessels. Common manifestations of this disease process affect the ear, nose, throat, upper and lower airways, and kidneys. Cardiac involvement has been reported in 6–44% of patients, primarily as coronary arteritis and pericarditis. A majority of case reports of pericardial effusions in patients with GPA identify patients having constrictive pericarditis secondary to uremia. We are presenting a case of hemorrhagic pericarditis in a patient with GPA in which the underlying inflammatory vasculitis likely played the primary role in the patient’s presentation. Echocardiographic abnormalities have been found in 80% of patients with GPA. Given the high mortality from cardiac involvement in patients with GPA, screening echocardiograms for this patient population may serve as a helpful tool in gauging disease severity, thereby guiding therapy to prevent serious cardiac complications, such as cardiac tamponade as presented in this case report.


2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Mihan Pourabdollah ◽  
Seyed Reza Saghebi ◽  
Mitra Abdolahi ◽  
Mitra Sadat Rezaei

Necrotizing sarcoid granulomatosis (NSG) is a rare granulomatous pneumonitis which is composed of a background of sarcoidosis-like granulomas, granulomatous vasculitis, and variable amount of necrosis. We reported a case of a 38-year-old nonsmoking woman presented with left-sided chest pain and dyspnea for three days. Chest CT scan exhibited collapse consolidation of the left lower lobe with the presence of two separated small-sized cystic lesions within the collapsed segment. Lung lesion resection was performed, and histological examination confirmed the diagnosis by excluding other causes of granulomatous diseases. The prognosis of NSG is favorable, and medical treatment is usually not necessary, as well as in our case. NSG is a rare disease with nonspecific symptoms and good prognosis which is frequently confused with Wegener’s granulomatosis, sarcoidosis, and Churg–Strauss syndrome. This entity should also be considered as differential diagnosis of necrotizing granulomatous diseases.


1981 ◽  
Vol 26 (3) ◽  
pp. 264-270 ◽  
Author(s):  
Robert Modigliani ◽  
Jean-Marie Muschart ◽  
Annie Galian ◽  
Jean-Pierre Clauvel ◽  
Jean-Luc Piel-Desruisseaux

2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Pedro Magalhães ◽  
Anabela Morais ◽  
Sofia Carvalho ◽  
Joana Cunha ◽  
Ana R. Lima ◽  
...  

Chest pain is one of the most frequent patient’s complaints. The commonest underlying causes are well known, but, sometimes, in some clinical scenarios, it is necessary to consider other diagnoses. We report a case of a 68-year-old Caucasian male, chronically hypertensive, who complained of recurrent episodes of chest pain and fever with elevated acute phase reactants. The first investigation was negative for some of the most likely diagnosis and he quickly improved with anti-inflammatory drugs. Over a few months, his symptoms continued to recur periodically, his hypertension was aggravated, and he developed headaches and lower limbs claudication. After a temporal artery biopsy that was negative for vasculitis, he underwent a positron emission tomography suggestive of Takayasu Arteritis. Takayasu Arteritis is a rare chronic granulomatous vasculitis of the aorta and its first-order branches affecting mostly females up to 50 years old. Chest pain is experienced by >40% of the patients and results from the inflammation of the aorta, pulmonary artery, or coronaries.


2003 ◽  
Vol 27 (6) ◽  
pp. 439-449 ◽  
Author(s):  
Samuel P. Hammar ◽  
M. Glenn Williams ◽  
Ronald F. Dodson

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