scholarly journals Necrotizing Sarcoid Granulomatosis with Pneumothorax

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Mihan Pourabdollah ◽  
Seyed Reza Saghebi ◽  
Mitra Abdolahi ◽  
Mitra Sadat Rezaei
Keyword(s):  
Lower Lobe ◽  
Good Prognosis ◽  
Lung Lesion ◽  
Chest Ct ◽  
Variable Amount ◽  
Granulomatous Vasculitis ◽  
Strauss Syndrome ◽  
Granulomatous Diseases ◽  
Churg Strauss ◽  
Chest Ct Scan

Necrotizing sarcoid granulomatosis (NSG) is a rare granulomatous pneumonitis which is composed of a background of sarcoidosis-like granulomas, granulomatous vasculitis, and variable amount of necrosis. We reported a case of a 38-year-old nonsmoking woman presented with left-sided chest pain and dyspnea for three days. Chest CT scan exhibited collapse consolidation of the left lower lobe with the presence of two separated small-sized cystic lesions within the collapsed segment. Lung lesion resection was performed, and histological examination confirmed the diagnosis by excluding other causes of granulomatous diseases. The prognosis of NSG is favorable, and medical treatment is usually not necessary, as well as in our case. NSG is a rare disease with nonspecific symptoms and good prognosis which is frequently confused with Wegener’s granulomatosis, sarcoidosis, and Churg–Strauss syndrome. This entity should also be considered as differential diagnosis of necrotizing granulomatous diseases.

Allergic granulomatous vasculitis (Churg-Strauss syndrome)

1981 ◽  
Vol 26 (3) ◽  
pp. 264-270 ◽  
Author(s):  
Robert Modigliani ◽  
Jean-Marie Muschart ◽  
Annie Galian ◽  
Jean-Pierre Clauvel ◽  
Jean-Luc Piel-Desruisseaux
Keyword(s):  
Churg Strauss Syndrome ◽  
Granulomatous Vasculitis ◽  
Strauss Syndrome ◽  
Churg Strauss

scholarly journals A retrospective study of the clinical characteristics of COVID-19 infection in 26 children

2020 ◽  
Author(s):  
Anjue Tang ◽  
Wenhui Xu ◽  
Min Shen ◽  
Peifen Chen ◽  
Guobao Li ◽  
...  
Keyword(s):  
Clinical Characteristics ◽  
Pediatric Patients ◽  
Clinical Symptoms ◽  
Good Prognosis ◽  
Chest Ct ◽  
Alanine Transaminase ◽  
Laboratory Results ◽  
Pulmonary Infiltration ◽  
Novel Coronavirus ◽  
Chest Ct Scan

ABSTRACTBackgroundThe outbreak of novel coronavirus pneumonia in China began in December 2019. Studies on novel coronavirus disease (COVID-19) were less based on pediatric patients. This study aimed to reveal the clinical characteristics of COVID-19 in children.MethodThis study retrospectively analyzed the clinical symptoms, laboratory results, chest CT, and treatment of children with laboratory-confirmed COVID-19(ie, with samples that were positive for 2019 novel coronavirus[2019-nCoV]) who were admitted to Shenzhen Center of National Infectious Disease Clinical Medical Research from January 16 to February 8, 2020.ResultNine patients had no obvious clinical symptom. 11 patients developed fever. Other symptoms, including cough(in eleven of seventeen patients), rhinorrhea(in two), diarrhea(in two), vomiting(in two), were also observed. A small minority of patients had lymphocytopenia. Alanine transaminase or transaminase increased in three cases. According to chest CT scan, 11 patients showed unilateral pneumonia, 8 patients had no pulmonary infiltration. No serious complications such as acute respiratory syndrome and acute lung injury occurred in all patients.ConclusionThe clinical characteristics of 2019-nCoV infection in children were different from adult. The overall condition of children were mild and have a good prognosis.MainpointCOVID-19 is a kind of new infectious disease.The clinical characteristics of 2019-nCoV infection in children may different from adult. Myocardium likely less affected by 2019-nCoV in children.

scholarly journals Total Lung and Lobar Quantitative Assessment Based on Paired Inspiratory–Expiratory Chest CT in Healthy Adults: Correlation with Pulmonary Ventilatory Function

Diagnostics ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 1791
Author(s):  
Feihong Wu ◽  
Leqing Chen ◽  
Jia Huang ◽  
Wenliang Fan ◽  
Jinrong Yang ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Ct Scan ◽  
Lung Volume ◽  
Significant Relationship ◽  
Lower Lobe ◽  
Chest Ct ◽  
Healthy Adults ◽  
Ventilatory Function ◽  
Quantitative Indexes ◽  
Chest Ct Scan

Objective: To provide the quantitative volumetric data of the total lung and lobes in inspiration and expiration from healthy adults, and to explore the value of paired inspiratory–expiratory chest CT scan in pulmonary ventilatory function and further explore the influence of each lobe on ventilation. Methods: A total of 65 adults (29 males and 36 females) with normal clinical pulmonary function test (PFT) and paired inspiratory–expiratory chest CT scan were retrospectively enrolled. The inspiratory and expiratory volumetric indexes of the total lung (TL) and 5 lobes (left upper lobe [LUL], left lower lobe [LLL], right upper lobe [RUL], right middle lobe [RML], and right lower lobe [RLL]) were obtained by Philips IntelliSpace Portal image postprocessing workstation, including inspiratory lung volume (LVin), expiratory lung volume (LVex), volume change (∆LV), and well-aerated lung volume (WAL, lung tissue with CT threshold between −950 and -750HU in inspiratory scan). Spearman correlation analysis was used to explore the correlation between CT quantitative indexes of the total lung and ventilatory function indexes (including total lung capacity [TLC], residual volume [RV], and force vital capacity [FVC]). Multiple stepwise regression analysis was used to explore the influence of each lobe on ventilation. Results: At end-inspiratory phase, the LVin-TL was 4664.6 (4282.7, 5916.2) mL, the WALTL was 4173 (3639.6, 5250.9) mL; both showed excellent correlation with TLC (LVin-TL: r = 0.890, p < 0.001; WALTL: r = 0.879, p < 0.001). From multiple linear regression analysis with lobar CT indexes as variables, the LVin and WAL of these two lobes, LLL and RUL, showed a significant relationship with TLC. At end-expiratory phase, the LVex-TL was 2325.2 (1969.7, 2722.5) mL with good correlation with RV (r = 0.811, p < 0.001), of which the LVex of RUL and RML had a significant relationship with RV. For the volumetric change within breathing, the ∆LVTL was 2485.6 (2169.8, 3078.1) mL with good correlation with FVC (r = 0.719, p < 0.001), moreover, WALTL showed a better correlation with FVC (r = 0.817, p < 0.001) than that of ∆LVTL. Likewise, there was also a strong association between ∆LV, WAL of these two lobes (LLL and RUL), and FVC. Conclusions: The quantitative indexes derived from paired inspiratory–expiratory chest CT could reflect the clinical pulmonary ventilatory function, LLL, and RUL give greater impact on ventilation. Thus, the pulmonary functional evaluation needs to be more precise and not limited to the total lung level.

scholarly journals CT features of mature teratoma in the mediastinum of two young adults—a report of two cases

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Naqibullah Foladi ◽  
Farhad Farzam ◽  
Najibullah Rahil ◽  
Mer Mahmood Shah Hoshang
Keyword(s):  
Germ Cell ◽  
Mature Teratoma ◽  
Germ Cell Tumors ◽  
Anterior Mediastinum ◽  
Good Prognosis ◽  
Chest Ct ◽  
Case Presentation ◽  
Superior Mediastinum ◽  
Chest Ct Scan ◽  
Ct Features

Abstract Background Germ cell tumors prefer gonadal regions, but they can be expected in extragonadal sites such as the anterior mediastinum, which is the commonly involved region after gonads. Amongst germ cell tumors, teratomas are the rarer subtypes which develop in the anterior mediastinum. Case presentation The authors present two adult patients, a male and a female, both complaining of chronic chest pain and cough. Chest CT scans were performed revealing characteristic CT features of mature teratomas in the anterior mediastinum which were extending to the superior mediastinum in both patients. Conclusion Germ cell tumors are involving the mediastinum; however, amongst all germ cell tumors, teratoma is the least common type arising in the mediastinum, and a chest CT scan considered the imaging investigation of choice. Surgery is the best option and patients may have a very good prognosis.

scholarly journals Chest computed tomography (CT) scan findings in patients with COVID-19: a systematic review and meta-analysis

2020 ◽  
Author(s):  
Mohammad Karimian ◽  
Milad Azami
Keyword(s):  
Computed Tomography ◽  
Ct Scan ◽  
Meta Analysis ◽  
Lower Lobe ◽  
Chest Ct ◽  
Transformation Rule ◽  
Cochrane Library ◽  
Final Report ◽  
Chest Computed Tomography ◽  
Chest Ct Scan

AbstractObjectivesNumerous cases of pneumonia of caused by coronavirus disease 2019 (COVID-19) were reported in Wuhan, China. Chest computed tomography (CT) scan is highly important in the diagnosis and follow-up of lung disease treatment. The present meta-analysis was performed to evaluate chest CT findings in COVID-19 patients.Materials and MethodsAll research steps were taken according to the MOOSE protocol and the final report was based on PRISMA guidelines. Each stage of the study was conducted by two independent authors. We searched the Web of Science, Ovid, Science Direct, Scopus, EMBASE, PubMed/Medline, Cochrane Library, EBSCO, CINAHL and Google scholar databases. The search was conducted on March 20, 2020. Grey literature was searched at medrxiv website. All analyses were performed using Comprehensive Meta-Analysis. The adapted Newcastle Ottawa Scale was used to evaluate the risk of bias. We registered this review at PROSPERO (registration number: CRD42019127858).ResultsFinally, 40 eligible studies with 4,183 patients with COVID-19 were used for meta- analysis. The rate of positive chest CT scan in patients with COVID-19 was 94.5% (95%CI: 91.7-96.3). Bilateral lung involvement, pure ground-glass opacity (GGO), mixed (GGO pulse consolidation or reticular), consolidation, reticular, and presence of nodule findings in chest CT scan of COVID-19 pneumonia patients were respectively estimated to be 79.1% (95% CI: 70.8- 85.5), 64.9% (95%CI: 54.1-74.4), 49.2% (95%CI: 35.7-62.8), 30.3% (95%CI: 19.6-43.6), 17.0% (95%CI: 3.9-50.9) and 16.6% (95%CI: 13.6-20.2). The distribution of lung lesions in patients with COVID-19 pneumonia was peripheral (70.0% [95%CI: 57.8-79.9]), central (3.9% [95%CI: 1.4-10.6]), and peripheral and central (31.1% [95%CI: 19.5-45.8]). The most common pulmonary lobes involved were right lower lobe (86.5% [95%CI: 57.7-96.8]) and left lower lobe (81.0% [95%CI: 50.5-94.7]).ConclusionOur study showed that chest CT scan has little weakness in diagnosis of COVID-19 combined to personal history, clinical symptoms, and initial laboratory findings, and may therefore serve as a standard method for diagnosis of COVID-19 based on its features and transformation rule, before initial RT-PCR screening.

Limited form of Churg-Strauss syndrome presenting as a mass in the neck

2002 ◽  
Vol 116 (11) ◽  
pp. 966-968 ◽  
Author(s):  
J. W. Moor ◽  
J. U-King Im ◽  
A. W. MacDonald ◽  
E. Whitehead
Keyword(s):  
Diagnostic Criteria ◽  
Systemic Vasculitis ◽  
Large Mass ◽  
Histological Diagnosis ◽  
Churg Strauss Syndrome ◽  
Granulomatous Vasculitis ◽  
Supraclavicular Fossa ◽  
Strauss Syndrome ◽  
Churg Strauss

A 53-year-old man was referred to the ENT department with a large mass in the left supraclavicular fossa. The histological diagnosis showed the mass to have arisen due to a granulomatous vasculitis consistent with Churg-Strauss syndrome (CSS). CSS usually comprises asthma, eosinophilia and systemic vasculitis although limited forms of the disease exist where one of these diagnostic criteria is missing. This is one such case as the patient was non-asthmatic.

scholarly journals Anti-neutrophil cytoplasmic antibody - negative Churg-Strauss syndrome presenting as non-healing ulcer on finger and associated lichen amyloidosis: a case report

2018 ◽  
Vol 4 (3) ◽  
pp. 437
Author(s):  
Sharim Fathima ◽  
Jisy S. R.
Keyword(s):  
Middle Finger ◽  
Antineutrophil Cytoplasmic Antibodies ◽  
Healing Ulcer ◽  
Churg Strauss Syndrome ◽  
Granulomatous Vasculitis ◽  
Life Threatening ◽  
History Of ◽  
Strauss Syndrome ◽  
Eosinophilic Granulomatosis ◽  
Churg Strauss

<p class="abstract">Churg Strauss syndrome (CSS) also known as eosinophilic granulomatosis with polyangitis (EGPA), is a rare disease manifested by hypereosinophilia, vasculitis and extravascular granuloma. We report a case of 72 year old male with history of asthma and allergic rhinitis who presented with non-healing ulcer on dorsum of left middle finger and petechial lesions on forearms. Investigations revealed marked eosinophilia, elevated IgE, negative antineutrophil cytoplasmic antibodies (ANCA), histopathologic examination showed granulomatous vasculitis and CSS was diagnosed using ACR criteria. We report this case because of rarity of disease and the importance of recognizing similar presentation for early diagnosis and treatment of this life threatening syndrome.</p>

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