Potential therapeutic implications of ergogenic compounds on pathophysiology induced by traumatic brain injury: A narrative review

Life Sciences ◽  
2019 ◽  
Vol 233 ◽  
pp. 116684
Author(s):  
Gustavo Cassol ◽  
Douglas Buchmann Godinho ◽  
Viviane Nogueira de Zorzi ◽  
Juliano Boufleur Farinha ◽  
Iuri Domingues Della-Pace ◽  
...  
2021 ◽  
Vol 11 (1) ◽  
pp. 18
Author(s):  
Edoardo Picetti ◽  
Israel Rosenstein ◽  
Zsolt J. Balogh ◽  
Fausto Catena ◽  
Fabio S. Taccone ◽  
...  

Managing the acute phase after a severe traumatic brain injury (TBI) with polytrauma represents a challenging situation for every trauma team member. A worldwide variability in the management of these complex patients has been reported in recent studies. Moreover, limited evidence regarding this topic is available, mainly due to the lack of well-designed studies. Anesthesiologists, as trauma team members, should be familiar with all the issues related to the management of these patients. In this narrative review, we summarize the available evidence in this setting, focusing on perioperative brain protection, cardiorespiratory optimization, and preservation of the coagulative function. An overview on simultaneous multisystem surgery (SMS) is also presented.


2021 ◽  
Vol 11 (3) ◽  
pp. 114
Author(s):  
Jian-Gang Liu ◽  
Hong-Wei Hu ◽  
Zhi-Guo Chen ◽  
Gang Chen

2018 ◽  
pp. 157-169

Vision problems are common in individuals with mild traumatic brain injury (mTBI)/concussion. However, a global conceptualization of the diagnostic process remains incomplete and practitioner dependent. Thus, a comprehensive diagnostic test battery is proposed to assist in the management of these patients. This battery includes a range of basic clinical tests of a sensory and motor nature, with all having a clinical and scientific rationale. These tests have been used by the authors for many years, with good success, and furthermore they have been found to be clinically useful and insightful.


2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Vijay Krishnamoorthy ◽  
Deepak Sharma ◽  
Sumidtra Prathep ◽  
Monica S. Vavilala

Traumatic brain injury (TBI) is a major public health issue and is a leading cause of death in North America. After a primary TBI, secondary brain insults can predispose patients to a worse outcome. One of the earliest secondary insults encountered during the perioperative period is hypotension, which has been directly linked to both mortality and poor disposition after TBI. Despite this, it has been shown that hypotension commonly occurs during surgery for TBI. We present a case of intraoperative hypotension during surgery for TBI, where the use of transthoracic echocardiography had significant diagnostic and therapeutic implications for the management of our patient. We then discuss the issue of cardiac dysfunction after brain injury and the implications that echocardiography may have in the management of this vulnerable patient population.


2019 ◽  
Vol 7 (1) ◽  
pp. 15-22
Author(s):  
Jason A. Hugentobler ◽  
Catherine Quatman-Yates ◽  
Nathan K. Evanson ◽  
Andrea Paulson ◽  
Caitlin Chicoine ◽  
...  

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