Inhibition of the sodium-translocating NADH-ubiquinone oxidoreductase [Na+-NQR] decreases cholera toxin production in Vibrio cholerae O1 at the late exponential growth phase

1AbstractAn automated statistical and error analysis of 45 countries or regions with more than 1000 cases of COVID-19 as of March 28, 2020, has been performed. This study reveals differences in the rate of disease spreading rate over time in different countries. This survey observes that most countries undergo a beginning exponential growth phase, which transitions into a power-law phase, as recently suggested by Ziff and Ziff. Tracking indicators of growth, such as the power-law exponent, are a good indication of the relative danger different countries are in and show when social measures are effective towards slowing the spread. The data compiled here are usefully synthesizing a global picture, identifying country to country variation in spreading, and identifying countries most at risk. This analysis may factor into how best to track the effectiveness of social distancing policies and quarantines in real-time as data is updated each day.

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Immunobiological relationships of the enterotoxins produced by cholera toxin gene-positive (CT+) and -negative (CT-) strains of Vibrio cholerae O1

Journal of Medical Microbiology ◽

10.1099/00222615-32-1-33 ◽

1990 ◽

Vol 32 (1) ◽

pp. 33-37 ◽

Cited By ~ 6

Author(s):

S. SAHA ◽

S. C. SANYAL

Keyword(s):

Cholera Toxin ◽

Vibrio Cholerae ◽

Toxin Gene ◽

Vibrio Cholerae O1

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Large production of cholera toxin by Vibrio cholerae O1 in yeast extract peptone water.

Journal of Clinical Microbiology ◽

10.1128/jcm.25.12.2314-2316.1987 ◽

1987 ◽

Vol 25 (12) ◽

pp. 2314-2316 ◽

Cited By ~ 29

Author(s):

M Iwanaga ◽

T Kuyyakanond

Keyword(s):

Cholera Toxin ◽

Vibrio Cholerae ◽

Yeast Extract ◽

Peptone Water ◽

Vibrio Cholerae O1 ◽

Large Production

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Cholera Toxin Production Induced upon Anaerobic Respiration is Suppressed by Glucose Fermentation in Vibrio cholerae

Journal of Microbiology and Biotechnology ◽

10.4014/jmb.1512.12039 ◽

2016 ◽

Vol 26 (3) ◽

pp. 627-636 ◽

Cited By ~ 5

Author(s):

Young Taek Oh ◽

Kang-Mu Lee ◽

Wasimul Bari ◽

Hwa Young Kim ◽

Hye Jin Kim ◽

...

Keyword(s):

Cholera Toxin ◽

Vibrio Cholerae ◽

Anaerobic Respiration ◽

Toxin Production ◽

Glucose Fermentation

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Biosynthesis and turnover of outer-membrane proteins in Escherichia coli ML308-225

Biochemical Journal ◽

10.1042/bj1820407 ◽

1979 ◽

Vol 182 (2) ◽

pp. 407-412 ◽

Cited By ~ 3

Author(s):

R J Allen ◽

G K Scott

Keyword(s):

Escherichia Coli ◽

Protein Synthesis ◽

Outer Membrane ◽

Bacterial Growth ◽

Growth Phase ◽

Exponential Growth ◽

Outer Membrane Proteins ◽

Exponential Growth Phase ◽

Outer Membranes ◽

Dilution Experiments

Isolated outer membranes and outer-membrane extracts from Escherichia coli ML308-225 in the early-exponential growth phase contain more protein than do corresponding preparations from late-exponential- or stationary-phase bacteria. Isotope-dilution experiments show that this is due to a loss of protein from the membrane during the exponential growth phase. Inhibition of bacterial growth and protein synthesis stabilizes the outer-membrane-protein concentration. Protein synthesis in the absence of bacterial growth results in higher concentrations of protein in the outer membrane.

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