Optimisation, evaluation and application of asymmetrical flow field-flow fractionation with single particle inductively coupled plasma mass spectrometry (SP-ICP-MS) to characterise silver nanoparticles in environmental media

Agreements and discrepancies are pointed out in the comparison between spICP-MS, AF4-MALLS-ICP-MS, and other routine techniques for nanoparticle sizing. Calibration protocols play an important role in analytical result quality.

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Results of an interlaboratory method performance study for the size determination and quantification of silver nanoparticles in chicken meat by single-particle inductively coupled plasma mass spectrometry (sp-ICP-MS)

Analytical and Bioanalytical Chemistry ◽

10.1007/s00216-017-0427-2 ◽

2017 ◽

Vol 409 (20) ◽

pp. 4839-4848 ◽

Cited By ~ 18

Author(s):

Stefan Weigel ◽

Ruud Peters ◽

Katrin Loeschner ◽

Ringo Grombe ◽

Thomas P. J. Linsinger

Keyword(s):

Mass Spectrometry ◽

Silver Nanoparticles ◽

Single Particle ◽

Inductively Coupled Plasma ◽

Size Determination ◽

Performance Study ◽

Method Performance ◽

Inductively Coupled ◽

Icp Ms ◽

Plasma Mass Spectrometry

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Characterization of silver nanoparticles using flow-field flow fractionation interfaced to inductively coupled plasma mass spectrometry

Journal of Chromatography A ◽

10.1016/j.chroma.2010.12.076 ◽

2011 ◽

Vol 1218 (27) ◽

pp. 4219-4225 ◽

Cited By ~ 133

Author(s):

A.R. Poda ◽

A.J. Bednar ◽

A.J. Kennedy ◽

A. Harmon ◽

M. Hull ◽

...

Keyword(s):

Mass Spectrometry ◽

Silver Nanoparticles ◽

Flow Field ◽

Inductively Coupled Plasma ◽

Field Flow Fractionation ◽

Inductively Coupled ◽

Plasma Mass Spectrometry ◽

Flow Fractionation

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Chemical speciation studies on DU contaminated soils using flow field flow fractionation linked to inductively coupled plasma mass spectrometry (FlFFF-ICP-MS)

Journal of Environmental Monitoring ◽

10.1039/c2em10716c ◽

2012 ◽

Vol 14 (3) ◽

pp. 782 ◽

Cited By ~ 10

Author(s):

S. R. Brittain ◽

A. G. Cox ◽

A. D. Tomos ◽

E. Paterson ◽

A. Siripinyanond ◽

...

Keyword(s):

Mass Spectrometry ◽

Flow Field ◽

Contaminated Soils ◽

Inductively Coupled Plasma ◽

Chemical Speciation ◽

Field Flow Fractionation ◽

Inductively Coupled ◽

Icp Ms ◽

Plasma Mass Spectrometry ◽

Flow Fractionation

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Challenges in Determining the Size Distribution of Nanoparticles in Consumer Products by Asymmetric Flow Field-Flow Fractionation Coupled to Inductively Coupled Plasma-Mass Spectrometry: The Example of Al2O3, TiO2, and SiO2 Nanoparticles in Toothpaste

Separations ◽

10.3390/separations5040056 ◽

2018 ◽

Vol 5 (4) ◽

pp. 56 ◽

Cited By ~ 7

Author(s):

Manuel Correia ◽

Toni Uusimäki ◽

Allan Philippe ◽

Katrin Loeschner

Keyword(s):

Mass Spectrometry ◽

Particle Size ◽

Flow Field ◽

Inductively Coupled Plasma ◽

Field Flow Fractionation ◽

Asymmetric Flow ◽

Inductively Coupled ◽

Icp Ms ◽

Plasma Mass Spectrometry ◽

Flow Fractionation

According to the current European regulation on cosmetics, any ingredient present as a nanomaterial should be indicated in the ingredient list. There is a need for analytical methods capable of determining the size of the relevant ingredients and thus assessing if these are nanomaterials or not. An analytical method based on asymmetric flow field-flow fractionation (AF4) and inductively coupled plasma-mass spectrometry (ICP-MS) was developed to determine the size of particles present in a commercial toothpaste. Multi-angle light scattering (MALS) was used for on-line size determination. The number-based particle size distributions (PSDs) of the particles were retrieved upon mathematical conversion of the mass-based PSDs recovered from the AF4-ICP-MS fractograms. AF4-ICP-MS allowed to separate and detect Al2O3 and TiO2 particles in the toothpaste and to retrieve a correct TiO2 number-based PSD. The potential presence of particles in the lower size range of the Al2O3 mass-based PSD had a strong impact on sizing and nanomaterial classification upon conversion. AF4 coupled with ICP-MS and MALS was found to be a powerful approach for characterization of different particles in a multiple-particle system such as toothpaste. Confirmation of particle size by a secondary method such as single particle ICP-MS or hydrodynamic chromatography was crucial.

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