Contribution of single particle inductively coupled plasma mass spectrometry and asymmetrical flow field-flow fractionation for the characterization of silver nanosuspensions. Comparison with other sizing techniques

2017 ◽  
Vol 32 (7) ◽  
pp. 1348-1358 ◽  
Author(s):  
S. Motellier ◽  
N. Pelissier ◽  
J. G. Mattei
Keyword(s):  
Mass Spectrometry ◽  
Flow Field ◽  
Single Particle ◽  
Inductively Coupled Plasma ◽  
Field Flow Fractionation ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry ◽  
Analytical Result

Agreements and discrepancies are pointed out in the comparison between spICP-MS, AF4-MALLS-ICP-MS, and other routine techniques for nanoparticle sizing. Calibration protocols play an important role in analytical result quality.

Joint forces of direct, single particle, CE– and HPLC–inductively coupled plasma mass spectrometry techniques for the examination of gold nanoparticle accumulation, distribution and changes inside human cells

Metallomics ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 408-415 ◽  
Author(s):  
Joanna Kruszewska ◽  
Dominika Kulpińska ◽  
Ilona Grabowska-Jadach ◽  
Magdalena Matczuk
Keyword(s):  
Mass Spectrometry ◽  
Gold Nanoparticle ◽  
Single Particle ◽  
Inductively Coupled Plasma ◽  
Human Cells ◽  
Inductively Coupled ◽  
Joint Forces ◽  
Icp Ms ◽  
Plasma Mass Spectrometry

ICP-MS-based platform for the characterization of medicinally attractive nanomaterials processing inside human cells.

scholarly journals Challenges in Determining the Size Distribution of Nanoparticles in Consumer Products by Asymmetric Flow Field-Flow Fractionation Coupled to Inductively Coupled Plasma-Mass Spectrometry: The Example of Al2O3, TiO2, and SiO2 Nanoparticles in Toothpaste

Separations ◽  
2018 ◽  
Vol 5 (4) ◽  
pp. 56 ◽  
Author(s):  
Manuel Correia ◽  
Toni Uusimäki ◽  
Allan Philippe ◽  
Katrin Loeschner
Keyword(s):  
Mass Spectrometry ◽  
Particle Size ◽  
Flow Field ◽  
Inductively Coupled Plasma ◽  
Field Flow Fractionation ◽  
Asymmetric Flow ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry ◽  
Flow Fractionation

According to the current European regulation on cosmetics, any ingredient present as a nanomaterial should be indicated in the ingredient list. There is a need for analytical methods capable of determining the size of the relevant ingredients and thus assessing if these are nanomaterials or not. An analytical method based on asymmetric flow field-flow fractionation (AF4) and inductively coupled plasma-mass spectrometry (ICP-MS) was developed to determine the size of particles present in a commercial toothpaste. Multi-angle light scattering (MALS) was used for on-line size determination. The number-based particle size distributions (PSDs) of the particles were retrieved upon mathematical conversion of the mass-based PSDs recovered from the AF4-ICP-MS fractograms. AF4-ICP-MS allowed to separate and detect Al2O3 and TiO2 particles in the toothpaste and to retrieve a correct TiO2 number-based PSD. The potential presence of particles in the lower size range of the Al2O3 mass-based PSD had a strong impact on sizing and nanomaterial classification upon conversion. AF4 coupled with ICP-MS and MALS was found to be a powerful approach for characterization of different particles in a multiple-particle system such as toothpaste. Confirmation of particle size by a secondary method such as single particle ICP-MS or hydrodynamic chromatography was crucial.

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