Histochemical and ultrastructural changes of sternomastoid muscle in aged wistar rats

Micron ◽  
2011 ◽  
Vol 42 (8) ◽  
pp. 871-876 ◽  
Author(s):  
Adriano Polican Ciena ◽  
Sonia Regina Yokomizo de Almeida ◽  
Paulo Henrique de Matos Alves ◽  
Regina de Sousa Bolina-Matos ◽  
Fernando José Dias ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Ultrastructural Changes ◽  
Sternomastoid Muscle

scholarly journals Fructose-Drinking Water Induced Nonalcoholic Fatty Liver Disease and Ultrastructural Alteration of Hepatocyte Mitochondria in Male Wistar Rat

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Norshalizah Mamikutty ◽  
Zar Chi Thent ◽  
Farihah Haji Suhaimi
Keyword(s):  
Metabolic Syndrome ◽  
Drinking Water ◽  
Liver Disease ◽  
Fatty Liver Disease ◽  
Wistar Rats ◽  
Wistar Rat ◽  
Ultrastructural Changes ◽  
Nonalcoholic Fatty Liver ◽  
The Metabolic Syndrome ◽  
Male Wistar Rats

Background.Nonalcoholic fatty liver disease (NAFLD) is one of the complications of the metabolic syndrome. It encompasses a wide range of disease spectrum from simple steatosis to liver cirrhosis. Structural alteration of hepatic mitochondria might be involved in the pathogenesis of NAFLD.Aims.In the present study, we used a newly established model of fructose-induced metabolic syndrome in male Wistar rats in order to investigate the ultrastructural changes in hepatic mitochondria that occur with fructose consumption and their association with NAFLD pathogenesis.Methods.The concentration of fructose-drinking water (FDW) used in this study was 20%. Six male Wistar rats were supplemented with FDW 20% for eight weeks. Body composition and metabolic parameters were measured before and after 8 weeks of FDW 20%. Histomorphology of the liver was evaluated and ultrastructural changes of mitochondria were assessed with transmission electron micrograph.Results.After 8 weeks of fructose consumption, the animals developed several features of the metabolic syndrome. Moreover, fructose consumption led to the development of macrovesicular hepatic steatosis and mitochondrial ultrastructural changes, such as increase in mitochondrial size, disruption of the cristae, and reduction of matrix density.Conclusion.We conclude that in male Wistar rat 8-week consumption of FDW 20% leads to NAFLD likely via mitochondrial structural alteration.

Toxicological effects and ultrastructural changes induced by lanthanum and cerium in ovary and uterus of Wistar rats

2017 ◽  
Vol 44 ◽  
pp. 349-355 ◽  
Author(s):  
Nedra Badri ◽  
Adrian Florea ◽  
Maroua Mhamdi ◽  
Horea Matei ◽  
Walid-Habib Tekaya ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Ultrastructural Changes ◽  
Toxicological Effects

scholarly journals Ultrastructural Changes in the Adenohypophysis, Adrenal Gland Activity, and Desynchronization of the Oestrous Cycle following Unpredictable Stress in the Rat

1977 ◽  
Vol 30 (6) ◽  
pp. 559 ◽  
Author(s):  
Irina Pollard ◽  
KD Cairncross
Keyword(s):  
Adrenal Gland ◽  
Ultrastructural Study ◽  
Wistar Rats ◽  
Secretory Activity ◽  
Cell Types ◽  
Ultrastructural Changes ◽  
Cellular Activity ◽  
Stressed Group ◽  
Female Wistar Rats ◽  
Circulating Levels

An ultrastructural study of the adenohypophysis, after exposure of female Wistar rats to a signaled unpredictable 5- and I5-day stress regimen, is described. Cellular activity of the adenohypophysis correlated well with the circulating levels of corticosterone. Intense secretory activity was observed in all tropic cell types at 5 and 15 days although the observed differences generally were greater in the 5-day stressed group. It was observed that the oestrous cycles of 40 and 100 % of the rats became desynchronized over the 5- and I5-day stress period respectively.

scholarly journals Continuous Electrical Current and Zinc Sulphate Administered by Transdermal Iontophoresis Improves Skin Healing in Diabetic Rats Induced by Alloxan: Morphological and Ultrastructural Analysis

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Lucas Langoni Cassettari ◽  
Pedro Colli Rocha Dias ◽  
Amanda Natália Lucchesi ◽  
Maurício Ferraz de Arruda ◽  
Érika Veruska Paiva Ortolan ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Breaking Strength ◽  
Electrical Current ◽  
Diabetic Rats ◽  
Ultrastructural Changes ◽  
Surgical Wounds ◽  
Male Wistar Rats ◽  
Transdermal Iontophoresis ◽  
Skin Healing ◽  
Stimulation Of

Purpose.Evaluated the effects of continuous electrical current (CEC) or zinc administrated by transdermal iontophoresis (Zn+TDI).Methods.120 male Wistar rats were submitted to an incision surgery at the anterior region of abdomen and distributed into 6 experimental groups with 40 animals: 3 diabetic groups and 3 normal groups, untreated and treated with CEC alone or with Zn + TDI. Each group was further divided into 4 subgroups with 10 rats each to be evaluated on the 4th, 7th, 14th, and 21st day after surgery. In each period, clinical and laboratory parameters from the animals were analyzed.Results. The analysis by optical and scanning electron microscopy showed a delay in the phases of wound healing in diabetic rats without treatment in all periods of the experiment; breaking strength (BS) was significantly reduced in skin scars of untreated diabetic rats when compared to other groups. In contrast, BS in skin scars of nondiabetic groups and diabetic rats treated with Zn + TDI showed significant increase in those, besides not presenting delayed healing.Conclusion. Electrical stimulation of surgical wounds used alone or in association with zinc by TDI is able to consistently improve the morphological and ultrastructural changes observed in the healing of diabetic animals.

Ultrastructural features of the myotendinous junction of the sternomastoid muscle in Wistar rats: From newborn to aging

2012 ◽  
Vol 75 (9) ◽  
pp. 1292-1296 ◽  
Author(s):  
Adriano Polican Ciena ◽  
Sonia Regina Yokomizo De Almeida ◽  
Cristina De Sousa Bolina ◽  
Regina De Sousa Bolina-Matos ◽  
Rose Eli Grassi Rici ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Myotendinous Junction ◽  
Sternomastoid Muscle

Ultrastructural Changes in Ageing Lacrimal Gland in Wistar Rats

2014 ◽  
Vol 157 (2) ◽  
pp. 268-272 ◽  
Author(s):  
V. B. Vais ◽  
I. M. Vangeli ◽  
L. E. Bakeeva
Keyword(s):  
Lacrimal Gland ◽  
Wistar Rats ◽  
Ultrastructural Changes

Fine Structural Changes in the Microvasculature of the Mouse Pinna: Aging and Radiation Injury

1974 ◽  
Vol 32 ◽  
pp. 54-55
Author(s):  
S. Phyllis Steamer ◽  
Rosemarie L. Devine
Keyword(s):  
Structural Changes ◽  
Radiation Treatment ◽  
Arterial Stenosis ◽  
Ultrastructural Changes ◽  
Vascular Effects ◽  
Microvascular Changes ◽  
Surrounding Connective Tissue ◽  
Fission Neutrons ◽  
Total Body

The importance of radiation damage to the skin and its vasculature was recognized by the early radiologists. In more recent studies, vascular effects were shown to involve the endothelium as well as the surrounding connective tissue. Microvascular changes in the mouse pinna were studied in vivo and recorded photographically over a period of 12-18 months. Radiation treatment at 110 days of age was total body exposure to either 240 rad fission neutrons or 855 rad 60Co gamma rays. After in vivo observations in control and irradiated mice, animals were sacrificed for examination of changes in vascular fine structure. Vessels were selected from regions of specific interest that had been identified on photomicrographs. Prominent ultrastructural changes can be attributed to aging as well as to radiation treatment. Of principal concern were determinations of ultrastructural changes associated with venous dilatations, segmental arterial stenosis and tortuosities of both veins and arteries, effects that had been identified on the basis of light microscopic observations. Tortuosities and irregularly dilated vein segments were related to both aging and radiation changes but arterial stenosis was observed only in irradiated animals.

Basal Lamina Formation in DMBA Induced Mammary Carcinoma

1977 ◽  
Vol 35 ◽  
pp. 534-535
Author(s):  
I. Russo ◽  
J. Saby ◽  
J. Russo
Keyword(s):  
Mammary Carcinoma ◽  
Virgin Female ◽  
Mammary Glands ◽  
Sesame Oil ◽  
Female Rats ◽  
Ultrastructural Changes ◽  
Post Inoculation ◽  
Intermediate Type ◽  
Sprague Dawley ◽  
Intercellular Spaces

It has been previously demonstrated that DMBA-induced rat mammary carcinoma originates in the terminal end bud (TEB) of the mammary gland by proliferation of intermediate type cells (1). The earliest lesion identified is the intraductal proliferation (IDP), which gives rise to intraductal carcinomas. These evolve to cribriform, papillary and comedo types (2). In the present work, we report the ultrastructural changes that take place in the IDP for the formation of a cribriform pattern.Fifty-five-day-old Sprague Dawley virgin female rats were inoculated intra- gastrically with 20 mg 7,12-dimethylbenz(a)anthracene (DMBA) in 1 ml sesame oil. Non-inoculated, age-matched females were used as controls. Mammary glands from both control and experimental rats were removed weekly from the time of inoculation until 86 days post-inoculation. The glands were fixed and processed for electron microscopy (2).The first change observed in IDP's was the widening of intercellular spaces and the secretion of an electron dense material into these spaces (Fig. 1).

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