Molecular characterisation and biological activity of an antiparasitic peptide from Sciaenops ocellatus and its immune response to Cryptocaryon irritans

2022 ◽  
Vol 141 ◽  
pp. 1-12
Author(s):  
Yuan Jin ◽  
Yong Mao ◽  
Su-Fang Niu ◽  
Ying Pan ◽  
Wei-Hao Zheng ◽  
...  
Keyword(s):  
Immune Response ◽  
Biological Activity ◽  
Sciaenops Ocellatus ◽  
Molecular Characterisation ◽  
Cryptocaryon Irritans

scholarly journals Extracellular Vesicles from Different Pneumococcal Serotypes Are Internalized by Macrophages and Induce Host Immune Responses

Pathogens ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1530
Author(s):  
Alfonso Olaya-Abril ◽  
Rafael Prados-Rosales ◽  
José A. González-Reyes ◽  
Arturo Casadevall ◽  
Liise-anne Pirofski ◽  
...  
Keyword(s):  
Immune Response ◽  
Biological Activity ◽  
Immune Responses ◽  
Extracellular Vesicles ◽  
Host Cells ◽  
Pneumococcal Serotypes ◽  
Human Pathogen ◽  
Host Immune Responses ◽  
Serotype 1 ◽  
Transient Loss

Bacterial extracellular vesicles are membranous ultrastructures released from the cell surface. They play important roles in the interaction between the host and the bacteria. In this work, we show how extracellular vesicles produced by four different serotypes of the important human pathogen, Streptococcus pneumoniae, are internalized by murine J774A.1 macrophages via fusion with the membrane of the host cells. We also evaluated the capacity of pneumococcal extracellular vesicles to elicit an immune response by macrophages. Macrophages treated with the vesicles underwent a serotype-dependent transient loss of viability, which was further reverted. The vesicles induced the production of proinflammatory cytokines, which was higher for serotype 1 and serotype 8-derived vesicles. These results demonstrate the biological activity of extracellular vesicles of clinically important pneumococcal serotypes.

Biological activity in Macrocystis pyrifera from Argentina: sodium alginate, fucoidan and laminaran. I. Antitumor, cytotoxicity and humoral immune response

Hydrobiologia ◽  
1987 ◽  
Vol 151-152 (1) ◽  
pp. 483-489 ◽  
Author(s):  
Alejandro M. S. Mayer ◽  
Liliana Krotz ◽  
R. Daniel Bonfil ◽  
Oscar D. Bustuobad ◽  
Jose F. Groisman ◽  
...  
Keyword(s):  
Immune Response ◽  
Biological Activity ◽  
Sodium Alginate ◽  
Humoral Immune Response ◽  
Macrocystis Pyrifera ◽  
Humoral Immune

Biological activity of analogs of the peptide hormone luliberin in the regulation of the immune response of T cells

1996 ◽  
Vol 122 (3) ◽  
pp. 943-946 ◽  
Author(s):  
T. B. Kazakova ◽  
S. V. Burov ◽  
O. I. Golovko ◽  
T. V. Grishina ◽  
N. S. Novikova ◽  
...  
Keyword(s):  
Immune Response ◽  
T Cells ◽  
Biological Activity ◽  
Peptide Hormone

Molecular characterisation and biological activity of a novel CXC chemokine gene in rock bream (Oplegnathus fasciatus)

2013 ◽  
Vol 34 (5) ◽  
pp. 1103-1111 ◽  
Author(s):  
Ju-Won Kim ◽  
Eun-Gyeong Kim ◽  
Do-Hyung Kim ◽  
Sang Hee Shim ◽  
Chan-Il Park
Keyword(s):  
Biological Activity ◽  
Molecular Characterisation ◽  
Oplegnathus Fasciatus ◽  
Chemokine Gene ◽  
Rock Bream ◽  
Cxc Chemokine

scholarly journals New analogue of cyclolinopeptide B modified by amphiphilic residue of alpha-hydroxymethylmethionine.

2004 ◽  
Vol 51 (1) ◽  
pp. 67-72 ◽  
Author(s):  
Renata Witkowska ◽  
Anna Donigiewicz ◽  
Michał Zimecki ◽  
Janusz Zabrocki
Keyword(s):  
Immune Response ◽  
Biological Activity ◽  
Humoral Immune Response ◽  
Immunosuppressive Activity ◽  
Humoral Immune ◽  
Methionine Residue ◽  
High Doses

In order to evaluate the role and influence of the methionine residue on the biological activity of cyclolinopeptide B, an analogue with methionine residue in position 7 replaced by the amphiphilic (S)-alpha-hydroxymethylmethionine residue was synthesized. This peptide exhibits high immunosuppressive activity in the cellular, and to a lesser degree in the humoral immune response, comparable to that of CsA. In addition, the peptide was devoid of toxicity, even at high doses.

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