Making bovine trypsin more stable and active by Erythritol: A multispectroscopic analysis, docking and computational simulation methods

2019 ◽  
Vol 292 ◽  
pp. 111389 ◽  
Author(s):  
Lida Momeni ◽  
Behzad Shareghi ◽  
Sadegh Farhadian ◽  
Fateme Raisi
2010 ◽  
Vol 4 (3) ◽  
pp. 396-401 ◽  
Author(s):  
Vladimír Kompiš ◽  
Zuzana Murčinková ◽  
Sergey Rjasanow ◽  
Richards Grzibovskis ◽  
Qinghua Qin

Author(s):  
Vladimír Kompiš ◽  
Zuzana Murčinková ◽  
Sergey Rjasanow ◽  
Richards Grzhibovskis ◽  
Qing-Hua Qin

2019 ◽  
Vol 52 (2) ◽  
pp. 114-124
Author(s):  
Sami Holopainen ◽  
Olli-Pekka Piirilä ◽  
Antti Salmela

"Patentability" refers to conditions laid down by law to what can be patented and what cannot. In this study, changes in the patentability of simulation methods are compared with the rapid development of computational science since 1970s. Although technological progress has caused computational simulation and modelling methods to grow to an everyday tool of technology, these methods have traditionally been excluded from patentability as "non-technical subject matter" or "abstract ideas". We describe the changes in patentability criteria in Europe and in the USA, and illustrate the development of patenting activity in this field during the last decade. Practisers should be aware of these changes, and investigate the possibilities they might offer.


2017 ◽  
Vol 3 (3) ◽  
pp. 374-384
Author(s):  
Jasrena Rohanapi ◽  
Mohamad Shukor Talib ◽  
Nurul Annasuha Mohd Baharudin

2014 ◽  
Vol 66 (6) ◽  
Author(s):  
Brian L. V. Bak ◽  
Carlos Sarrado ◽  
Albert Turon ◽  
Josep Costa

Advanced design methodologies enable lighter and more reliable composite structures or components. However, efforts to include fatigue delamination in the simulation of composites have not yet been consolidated. Besides that, there is a lack of a proper categorization of the published methods in terms of their predictive capabilities and the principles they are based on. This paper reviews the available experimental observations, the phenomenological models, and the computational simulation methods for the three phases of delamination (initiation, onset, and propagation). It compiles a synthesis of the current state-of-the-art while identifying the unsolved problems and the areas where research is missing. It is concluded that there is a lack of knowledge, or there are unsolved problems, in all categories in the field, but particularly in the category of computational methods, which in turn prevents its inclusion in the structural design process. Suggested areas where short-term and midterm research should be focused to overcome the current situation are identified.


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