A simple methyl substitution of 3-acetylcoumarin thiosemicarbazone enhances cellular autophagy flux, reduces inflammation and ameliorates rough eye phenotype in the Drosophila model of Alzheimer's disease

2021 ◽  
Vol 1235 ◽  
pp. 130265
Author(s):  
Mokshada Varma ◽  
Bhupendra Shravage ◽  
Sakharam Tayade ◽  
Avinash Kumbhar ◽  
Ray Butcher ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Autophagy Flux ◽  
Methyl Substitution ◽  
Model Of Alzheimer’S Disease ◽  
Cellular Autophagy ◽  
Drosophila Model

scholarly journals GULP1/CED-6 ameliorates amyloid-β toxicity in a Drosophila model of Alzheimer’s disease

Oncotarget ◽  
2017 ◽  
Vol 8 (59) ◽  
pp. 99274-99283 ◽  
Author(s):  
Wai Yin Vivien Chiu ◽  
Alex Chun Koon ◽  
Jacky Chi Ki Ngo ◽  
Ho Yin Edwin Chan ◽  
Kwok-Fai Lau
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Amyloid Β ◽  
Model Of Alzheimer’S Disease ◽  
Drosophila Model

scholarly journals Apolipoprotein E-Mimetics Inhibit Neurodegeneration and Restore Cognitive Functions in a Transgenic Drosophila Model of Alzheimer's Disease

PLoS ONE ◽  
2009 ◽  
Vol 4 (12) ◽  
pp. e8191 ◽  
Author(s):  
Svetlana Sarantseva ◽  
Svetlana Timoshenko ◽  
Olga Bolshakova ◽  
Eugenia Karaseva ◽  
Dmitry Rodin ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Apolipoprotein E ◽  
Cognitive Functions ◽  
Model Of Alzheimer’S Disease ◽  
Drosophila Model ◽  
Transgenic Drosophila

scholarly journals Mitochondrial Mislocalization Underlies Aβ42-Induced Neuronal Dysfunction in a Drosophila Model of Alzheimer's Disease

PLoS ONE ◽  
2009 ◽  
Vol 4 (12) ◽  
pp. e8310 ◽  
Author(s):  
Kanae Iijima-Ando ◽  
Stephen A. Hearn ◽  
Christopher Shenton ◽  
Anthony Gatt ◽  
LiJuan Zhao ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Neuronal Dysfunction ◽  
Model Of Alzheimer’S Disease ◽  
Drosophila Model

scholarly journals Genetic Inhibition of Solute-Linked Carrier 39 Family Transporter 1 Ameliorates Aβ Pathology in a Drosophila Model of Alzheimer's Disease

PLoS Genetics ◽  
2012 ◽  
Vol 8 (4) ◽  
pp. e1002683 ◽  
Author(s):  
Minglin Lang ◽  
Lei Wang ◽  
Qiangwang Fan ◽  
Guiran Xiao ◽  
Xiaoxi Wang ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Model Of Alzheimer’S Disease ◽  
Drosophila Model

Aβ exacerbates the neuronal dysfunction caused by human tau expression in a Drosophila model of Alzheimer's disease

2010 ◽  
Vol 223 (2) ◽  
pp. 401-409 ◽  
Author(s):  
James Folwell ◽  
Catherine M. Cowan ◽  
Kiren K. Ubhi ◽  
Hassan Shiabh ◽  
Tracey A. Newman ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Neuronal Dysfunction ◽  
Model Of Alzheimer’S Disease ◽  
Drosophila Model ◽  
Tau Expression

scholarly journals Synaptic abnormalities in a Drosophila model of Alzheimer's disease

2014 ◽  
Vol 7 (3) ◽  
pp. 373-385 ◽  
Author(s):  
S. D. Mhatre ◽  
V. Satyasi ◽  
M. Killen ◽  
B. E. Paddock ◽  
R. D. Moir ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Model Of Alzheimer’S Disease ◽  
Drosophila Model
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