scholarly journals Corrigendum to “Radiomic machine learning for pretreatment assessment of prognostic risk factors for endometrial cancer and its effects on radiologists' decisions of deep myometrial invasion” [Magnetic Resonance Imaging 85 (2022) 161–167].

2022 ◽  
Author(s):  
Satoshi Otani ◽  
Yuki Himoto ◽  
Mizuho Nishio ◽  
Koji Fujimoto ◽  
Yusaku Moribata ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Machine Learning ◽  
Risk Factors ◽  
Endometrial Cancer ◽  
Magnetic Resonance ◽  
Myometrial Invasion ◽  
Resonance Imaging ◽  
Pretreatment Assessment ◽  
Deep Myometrial Invasion ◽  
Prognostic Risk Factors

scholarly journals Tumoral volume measured preoperatively by magnetic resonance imaging is related to survival in endometrial cancer

2021 ◽  
Vol 55 (1) ◽  
pp. 35-41
Author(s):  
Pluvio J. Coronado ◽  
Javier de Santiago-López ◽  
Javier de Santiago-García ◽  
Ramiro Méndez ◽  
Maria Fasero ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Endometrial Cancer ◽  
Magnetic Resonance ◽  
Auxiliary Information ◽  
Myometrial Invasion ◽  
Figo Stage ◽  
Mri Imaging ◽  
Resonance Imaging ◽  
Deep Myometrial Invasion ◽  
Grade 3

AbstractBackgroundThe aim of the study was to determine if the endometrial tumor volume (TV) measured by magnetic resonance imaging (MRI-TV) is associated with survival in endometrial cancer and lymph nodes metastases (LN+).Patients and methodsWe evaluated the MRI imaging and records of 341 women with endometrial cancer and preoperative MRI from 2008 to 2018. The MRI-TV was calculated using the ellipsoid formula measuring three perpendicular tumor diameters. Tumor myometrial invasion was also analyzed.ResultsHigher MRI-TV was associated with age ≥ 65y, non-endometrioid tumors, grade-3, deep-myometrial invasion, LN+ and advanced FIGO stage. There were 37 patients with LN+ (8.8%). Non-endometrioid tumors, deep-myometrial invasion, grade-3 and MRI-TV ≥ 10 cm3 were the factors associated with LN+. Using a receiver operating characteristic [ROC] curve, the MRI-TV cut-off for survival was 10 cm3 (area under curve [AUC] = 0.70; 95% CI: 0.61–0.73). 5 years disease-free (DFS) and overall survival (OS) was significantly lower in MRI-TV ≥ 10 cm3 (69.3% vs. 84.5%, and 75.4% vs. 96.1%, respectively). MRI-TV was considered an independent factor of DFS (HR: 2.20, 95% CI: 1.09–4.45, p = 0.029) and OS (HR: 3.88, 95% CI: 1.34–11.24, p = 0.012) in multivariate analysis.ConclusionsMRI-TV was associated with LN+, and MRI-TV ≥ 10 cm3 was an independent prognostic factor of lower DFS and OS. The MRI-TV can be auxiliary information to plan the surgery strategy and predict the adjuvant treatment in women with endometrial cancer.

EVALUATION OF MYOMETRIAL INVASION AND CERVICAL INVOLVEMENT IN TYPE I ENDOMETRIAL CANCER USING DIFFUSION-WEIGHTED MAGNETIC RESONANCE IMAGING

2020 ◽  
pp. 4-6
Author(s):  
HARIYONO WINARTO ◽  
BRIAN PRIMA ARTHA ◽  
SAHAT B. MATONDANG ◽  
TANTRI HELLYANTI ◽  
ARIA KEKALIH
Keyword(s):  
Magnetic Resonance Imaging ◽  
Endometrial Cancer ◽  
Magnetic Resonance ◽  
Cancer Patients ◽  
Myometrial Invasion ◽  
Type I ◽  
Resonance Imaging ◽  
Diffusion Weighted ◽  
Weighted Magnetic Resonance Imaging ◽  
Cervical Involvement

Objective: Surgical procedure and adjuvant treatment of type I endometrial cancer were affected by some variables assessed preoperatively. Diffusion-weighted magnetic resonance imaging (DWI) is a promising modality in evaluating myometrial invasion and cervical involvement, investigating the diagnostic values of DWI in assessing myometrial invasion and cervical involvement. Methods: A cross-sectional study was conducted. This study involved all type I endometrial cancer patients in Dr. Cipto Mangunkusumo Hospital from April 2016 until April 2019. The depth of myometrial invasion and cervical involvement was examined using 1.5-T MR unit. The result was compared to the surgical pathologic findings as the reference standard. Results: 34 types I endometrial cancer patients were enrolled in this study. The sensitivity of DWI in evaluating myometrial invasion and cervical involvement in type I endometrial cancer was 94.12% and 57.14%, while the specificity was 64.71% and 92.59%, respectively. Conclusion: DWI can provide reliable prognostic variable information about the myometrial invasion and cervical involvement in the preoperative preparation of endometrial cancer patients.

Analysis of Prognostic Risk Factors in Patients with Nasopharyngeal Carcinoma Treated with Radiotherapy by Magnetic Resonance Imaging

2020 ◽  
Vol 10 (9) ◽  
pp. 2079-2083
Author(s):  
Jie Qi ◽  
Mang Xiao ◽  
Sharma Vikas
Keyword(s):  
Magnetic Resonance Imaging ◽  
Risk Factors ◽  
Survival Rate ◽  
Magnetic Resonance ◽  
Nasopharyngeal Carcinoma ◽  
Resonance Imaging ◽  
Residual Rate ◽  
Free Survival ◽  
N Stage ◽  
Prognostic Risk Factors

The purpose of the study was to explore the application value of magnetic resonance imaging (MRI) technology in the study of the prognosis of patients with nasopharyngeal carcinoma (NPC) after radiotherapy, and to analyze the risk factors leading to imaging residues, so as to provide reference for the treatment and prognosis of patients with NPC. The clinical data of 691 patients with NPC hospitalized from June 2008 to June 2016 were retrospectively analyzed. According to the results of magnetic resonance medical imaging, the residual data of patients with NPC after treatment were analyzed. Combined with t-stage and n-stage parameters, the image residual was divided into t-stage residual and n-stage residual. The radiological residues, residual regression time, survival time, recurrence and metastasis time were recorded. The radiological residual rate of NPC after radiotherapy was calculated, and the differences among groups were compared by chi-square test. The risk factors of image residual and residual regression time were analyzed by logistic regression model. The 5-year overall survival rate (OS), 5-year recurrence-free survival rate (LRFS), and 5-year distant metastasis-free survival rate (DMF) were calculated. Kaplan.Meier method was used to analyze the influence of various factors on the prognosis of patients, and logarithmic rank test was used to compare the difference of survival rate between the two groups. The results showed that the residual rate of T and N was 32.9% and 31.0% at the end of radiotherapy for NPC. In summary, magnetic resonance medical imaging technology can effectively evaluate the prognostic risk factors of patients with NPC after radiotherapy. Male, elderly, radioactivity residue, and high stage are the risk factors affecting the prognosis of patients with NPC after radiotherapy. The recurrence and metastasis of NPC patients can be effectively controlled by means of emphasizing radiotherapy combined with adjuvant chemotherapy.

Diagnostic Accuracy of Magnetic Resonance Imaging in Endometrial Cancer

2012 ◽  
Vol 22 (6) ◽  
pp. 1020-1025 ◽  
Author(s):  
Mark H. McComiskey ◽  
W. Glenn McCluggage ◽  
Arthur Grey ◽  
Ian Harley ◽  
Stephen Dobbs ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Endometrial Cancer ◽  
Magnetic Resonance ◽  
Diagnostic Accuracy ◽  
Predictive Value ◽  
Myometrial Invasion ◽  
Preoperative Assessment ◽  
Tumor Board ◽  
Resonance Imaging ◽  
Outer Half

ObjectivesThe objectives of this study were to investigate the accuracy of magnetic resonance imaging (MRI) in predicting the depth of myometrial invasion in the preoperative assessment of women with endometrial cancer and to quantify the impact of MRI as an adjunct to predicting patients requiring full surgical staging.MethodsThis was a diagnostic accuracy study of prospective cases in conjunction with STARD guidelines using collected data from a tumor board within a cancer network. Consecutive series of all endometrial cancers in Northern Ireland over a 21-month period was discussed at the Gynaecological Oncology Multidisciplinary Team/tumor board meeting. This study concerns 183 women who met all the inclusion criteria. Main outcome measure was the correlation between the depth of myometrial invasion suggested by preoperative MRI study and the subsequent histopathological findings following examination of the hysterectomy specimen. Secondary end point was how MRI changed management of women who required surgery to be performed at a central cancer center.ResultsFor the detection of outer-half myometrial invasion, overall sensitivity of MRI was 0.73 (95% confidence interval [CI], 0.59–0.83), and specificity was 0.83 (95% CI, 0.76–0.89). The positive predictive value was 0.63 (95% CI, 0.50–0.74), and negative predictive value was 0.89 (95% CI, 0.82–0.93). Positive likelihood ratio was 4.35 (95% CI, 2.87–6.61), and negative likelihood ratio was 0.33 (95% CI, 0.21–0.52). Magnetic resonance imaging improved the sensitivity and negative predictive value of endometrial biopsy alone in predicting women with endometrial cancer who require full surgical staging (0.73 vs 0.65 and 0.80 vs 0.78, respectively).ConclusionsPreoperative pelvic MRI is a moderately sensitive and specific method of identifying invasion to the outer half of myometrium in endometrial cancer. Addition of MRI to preoperative assessment leads to improved preoperative assessment, triage, and treatment.

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