Effect of Ti +4 on in vitro bioactivity and antibacterial activity of silicate glass-ceramics

2016 ◽  
Vol 69 ◽  
pp. 1058-1067 ◽  
Author(s):  
Madeeha Riaz ◽  
Rehana Zia ◽  
Farhat Saleemi ◽  
Tousif Hussain ◽  
Farooq Bashir ◽  
...  
2017 ◽  
Vol 31 (01) ◽  
pp. 1650246
Author(s):  
Madeeha Riaz ◽  
Rehana Zia ◽  
Farhat Saleemi

In the present study, two novel silicate glass-ceramics having chemical composition 38SiO2–41CaO–6P2O5–([Formula: see text])Na2O–[Formula: see text]CaF2 ([Formula: see text], 0.43 mol%) were synthesized. These glass derivatives were subjected to stimulated body fluid for 24 days in SBF under static condition at [Formula: see text]C in order to evaluate the bioactive properties of specimens. The antibacterial activity of glass ceramics against three pathogenic bacteria was determined using the modified Kirby Bauer method. It was found that the antibacterial activity primarily depends on the dissolution rate; faster release of ions caused rapid increase in the pH of the solution. Antibacterial properties were found to be strongly affected by changes in the pH of supernatant. The in vitro bioactivity assays showed that both glass derivatives were capable of bonding with bone and secondly effectively inhibit bacteria. However, the glass ceramic without CaF2 (B2) showed high dissolution rate, better bioactive ability and stronger antibacterial efficacy.


Author(s):  
Gultekin Göller ◽  
Ipek Akin ◽  
A. Kahraman ◽  
Erdem Demirkesen ◽  
M. Urgen

2010 ◽  
Vol 36 (6) ◽  
pp. 1757-1766 ◽  
Author(s):  
C.P. Yoganand ◽  
V. Selvarajan ◽  
Valeria Cannillo ◽  
Antonella Sola ◽  
E. Roumeli ◽  
...  

2006 ◽  
Vol 309-311 ◽  
pp. 325-328 ◽  
Author(s):  
Gültekin Göller ◽  
Ipek Akin ◽  
A. Kahraman ◽  
Erdem Demirkesen ◽  
M. Urgen

In this study; in-vitro bioactivity characterization of machinable glass-ceramics having 85 wt% sodium mica (NaMg3AlSi3O10F2) and 15 wt% fluoroapatite has been carried out. Two different heat treatment procedures are applied to the machinable glass-ceramics. The first one is nucleation at 610°C for 2 hours and crystallization at 1000°C for 3 hours and the second is nucleation at 610°C for 2 hours and crystallization at 1000°C for 4 hours. It is observed that increasing the crystallization time to 4 hours resulted in the increasing the formation of hydroxyapatite layer on surface. According to the microstructural investigations, the morphology of the precipitated crystals are different. In addition, the speed of the precipitation of hydroxyapatite is higher in glass-ceramic B than A. Thin film XRD analysis supports these results.


Materials ◽  
2017 ◽  
Vol 10 (4) ◽  
pp. 425 ◽  
Author(s):  
Amanda De Castro Juraski ◽  
Andrea Cecilia Dorion Rodas ◽  
Hamada Elsayed ◽  
Enrico Bernardo ◽  
Viviane Oliveira Soares ◽  
...  

2012 ◽  
Vol 10 (6) ◽  
pp. 1890-1898 ◽  
Author(s):  
Gabriela Lutišanová ◽  
Martin Palou ◽  
Milan Mikula ◽  
Jana Kozánková

AbstractThe present paper reports the results of the relationship between the surface topography, microstructure and the in vitro bioactivity of samples with and without fluorapatite content in simulated body fluid. Glasses and glass ceramics belonging to the Li2O-SiO2-CaO-P2O5-CaF2 system were prepared by using conventional melting technique following by heat treatment to obtain glass ceramics. This current study demonstrates the benefits of combining two microscopic methods for better investigation of the surface structure. The formation of apatite layer on the surface and the increase in surface roughness proved that the glasses and glass ceramics with bioactive fluorapatite content could satisfy to the requirements for biomaterial applications. The results also showed that the roughness of apatite layer formed after immersion in body fluid on the surface of glasses with fluorapatite was more pronounced than that of equivalent glass ceramic samples cured under the same conditions.


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