Association between serum beta-human chorionic gonadotropin and inflammation, oxidative stress in pregnancy-induced hypertension

2020 ◽  
pp. 104130
Author(s):  
Ruijuan Wang ◽  
Li Chen ◽  
Xiaobing Wang ◽  
Yanjun Liu
Keyword(s):  
Oxidative Stress ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Pregnancy Induced Hypertension ◽  
Beta Human Chorionic Gonadotropin ◽  
Induced Hypertension ◽  
In Pregnancy

scholarly journals Cardiac troponins and oxidative stress markers in non-pregnant, pregnant and preeclampsia women

2010 ◽  
Vol 36 (1) ◽  
pp. 4-9 ◽  
Author(s):  
Palanisamy Pasupathi ◽  
Uma Manivannan ◽  
Perisamy Manivannan ◽  
Mathiyalagan Deepa
Keyword(s):  
Oxidative Stress ◽  
Troponin I ◽  
Troponin T ◽  
Enzymatic Antioxidants ◽  
Pregnancy Induced Hypertension ◽  
Oxidative Stress Markers ◽  
Stress Markers ◽  
Induced Hypertension ◽  
And Oxidative Stress ◽  
In Pregnancy

Free radicals play an important role in the pathogenesis of tissue damage in many clinical disorders, including atherosclerosis. This study was to investigate lipids and oxidative stress markers among women with 50 healthy non-pregnant compare with 50 healthy pregnant and 50 pregnancy-induced hypertensive subjects and correlate with cardiac troponin I (cTnI) and troponin T (cTnT). The level of plasma thiobarbituric acid reactive substances (TBARS), cTnI and cTnT levels significantly increase in pregnancy-induced hypertension compare with other groups. The level of lipids significantly altered in pregnancy-induced hypertension. Conversely, the activities of both enzymatic and non-enzymatic antioxidants were significantly decreased in pregnancy-induced hypertension compared to non-pregnant and healthy pregnant. Our data suggest that there is an imbalance between lipoperoxidation and antioxidants levels during pregnancy and preeclampsia. Serum cTnI and cTnT are elevated in women with pregnancy-induced hypertension indicating some degree of cardiac myofibrillar damage and cardiac dysfunction.Online: 11 July 2010DOI: http://dx.doi.org/10.3329/bmrcb.v36i1.4806Bangladesh Med Res Counc Bull 2010; 36: 4-9

scholarly journals Visfatin gene expression and oxidative stress in pregnancy induced hypertension

2018 ◽  
Vol 5 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Hanan M.A. El-Taweel ◽  
Nevein A. Salah ◽  
Amal K. Selem ◽  
A.A. El-Refaeey ◽  
A.F. Abdel-Aziz
Keyword(s):  
Oxidative Stress ◽  
Gene Expression ◽  
Pregnancy Induced Hypertension ◽  
Induced Hypertension ◽  
And Oxidative Stress ◽  
In Pregnancy

scholarly journals Evaluation of oxidative stress in pregnancy induced hypertension

2006 ◽  
Vol 21 (1) ◽  
pp. 101-105 ◽  
Author(s):  
S. Mohanty ◽  
P. K. Sahu ◽  
M. K. Mandal ◽  
P. C. Mohapatra ◽  
A. Panda
Keyword(s):  
Oxidative Stress ◽  
Pregnancy Induced Hypertension ◽  
Induced Hypertension ◽  
In Pregnancy

scholarly journals The possibility of clinical use for the oxidative stress marker in correlation with blood flow parameters in pregnancy-induced hypertension

2021 ◽  
Vol 29 (2) ◽  
pp. 143-151
Author(s):  
Dragica Draganovic ◽  
Branka Cancarevic-Djajic ◽  
Dragica Jojic ◽  
Vesna Ljubojevic ◽  
Jelena Todorovic
Keyword(s):  
Oxidative Stress ◽  
Blood Flow ◽  
Pregnant Women ◽  
Umbilical Artery ◽  
Oxidative Stress Marker ◽  
Pregnancy Induced Hypertension ◽  
Diastolic Flow ◽  
Induced Hypertension ◽  
Tbars Values ◽  
In Pregnancy

Abstract Introduction: In pregnancy-induced hypertension (PIH) there is a disorder in placental blood flow which causes intrauterine fetal hypoxia, and oxidative stress has a significant role in this condition. The aims of this research were to analyze the relation of thiobarbituric acid reactive substance (TBARS), as a marker of oxidative stress and absent end-diastolic flow (AEDF), as well as the relation of TBARS and cerebroplacental ratio (CPR). Methods: The research included 200 pregnant women in the gestation period from 28th to 40th, 100 were in a control group and 100 were with PIH. The CPR and TBARS were analyzed in all examined pregnant women. The CPR was calculated by dividing the Doppler indices of the middle cerebral artery by the umbilical artery. Results: Mean value of TBARS in the group with the PIH who had AEDF was in the interval of high values - 43.22 μmol/l. The result shows that through the application of Spearman’s coefficient, the correlation results in a statistically significant correlation between CPR and TBARS values: ρ = - 0.249, p = 0.0001. Conclusion: PIH has a very high level of oxidative stress, especially in pregnant women with absent end-diastolic flow in the umbilical artery and pathologic CPR. The Spearman’s test results in statistical significance and negative correlation, which means that in higher TBARS values, values of CPR are lower and vice versa, which indicates a possibility of clinical application of TBARS.

scholarly journals Serum β-hCG Levels Between 13-20 Weeks Gestation Can Predict Development of Pregnancy Induced Hypertension

2018 ◽  
Vol 13 (1) ◽  
pp. 12-14
Author(s):  
Gurpreet Kour ◽  
Sandeep Kour
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Predictive Value ◽  
Pregnancy Induced Hypertension ◽  
Median Score ◽  
Pregnant Females ◽  
Induced Hypertension ◽  
Β Hcg

Aims: To find out predictive value of Serum β Human Chorionic Gonadotropin (β HCG) levels between 13-20 weeks of gestation in predicting the development of pregnancy induced hypertension (PIH) or pre-eclampsia, eclampsia.Methods: Serum β HCG level was estimated in 200 normotensive patients between 13-20 weeks of gestation. The median value of Serum β HCG was calculated and patients were divided into two groups as per two times Multiple of Median (2MOM) values of Serum β HCG i.e. those above and below the 2MOM values. The patients were followed up to delivery and were evaluated for the development of PIH, pre-eclampsia and eclampsia.Results: As per the median score of Serum β HCG in studied patients, the determined value of 2MOM was 30845 mIU/ml.  Out of 200 patients, 23 (11.5%) patients were found to have values of Serum β HCG ≥ 2MOM. Twelve (52%) patients in Serum β HCG ≥ 2MOM group developed hypertension on follow up as compared to 13 (7.3%) patients in < 2MOM group (p< 0.0001). Also patients in the ≥ 2MOM group had higher prevalence of maternal and fetal complications.Conclusion: Serum β HCG levels between 13-20 weeks of gestation can predict development of PIH  in pregnant females

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