scholarly journals Exosome reduction in vivo is associated with lower amyloid plaque load in the 5XFAD mouse model of Alzheimer's disease

2014 ◽  
Vol 35 (8) ◽  
pp. 1792-1800 ◽  
Author(s):  
Michael B. Dinkins ◽  
Somsankar Dasgupta ◽  
Guanghu Wang ◽  
Gu Zhu ◽  
Erhard Bieberich
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Mouse Model ◽  
Amyloid Plaque ◽  
Model Of Alzheimer’S Disease ◽  
Plaque Load ◽  
5Xfad Mouse

scholarly journals Bacterial sepsis increases hippocampal fibrillar amyloid plaque load and neuroinflammation in a mouse model of Alzheimer's disease

2021 ◽  
Vol 152 ◽  
pp. 105292
Author(s):  
Jacob M. Basak ◽  
Aura Ferreiro ◽  
Lucy S. Cohen ◽  
Patrick W. Sheehan ◽  
Collin J. Nadarajah ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Mouse Model ◽  
Amyloid Plaque ◽  
Bacterial Sepsis ◽  
Model Of Alzheimer’S Disease ◽  
Plaque Load

scholarly journals Hippocampal Neuron Loss Exceeds Amyloid Plaque Load in a Transgenic Mouse Model of Alzheimer's Disease

2004 ◽  
Vol 164 (4) ◽  
pp. 1495-1502 ◽  
Author(s):  
Christoph Schmitz ◽  
Bart P.F. Rutten ◽  
Andrea Pielen ◽  
Stephanie Schäfer ◽  
Oliver Wirths ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Mouse Model ◽  
Transgenic Mouse ◽  
Hippocampal Neuron ◽  
Amyloid Plaque ◽  
Transgenic Mouse Model ◽  
Neuron Loss ◽  
Model Of Alzheimer’S Disease ◽  
Plaque Load

scholarly journals A rationally designed small molecule for identifying an in vivo link between metal–amyloid-β complexes and the pathogenesis of Alzheimer's disease

2015 ◽  
Vol 6 (3) ◽  
pp. 1879-1886 ◽  
Author(s):  
Michael W. Beck ◽  
Shin Bi Oh ◽  
Richard A. Kerr ◽  
Hyuck Jin Lee ◽  
So Hee Kim ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Mouse Model ◽  
Small Molecule ◽  
Amyloid Β ◽  
Model Of Alzheimer’S Disease ◽  
5Xfad Mouse ◽  
Target Metal

An in vivo chemical tool designed to target metal−Aβ complexes and modulate their activity was applied to the 5XFAD mouse model of Alzheimer’s disease (AD) demonstrating the involvement of metal−Aβ in AD pathology.

scholarly journals P2-021: A method to quantitate amyloid plaque load in a transgenic mouse model of Alzheimer's disease

2008 ◽  
Vol 4 ◽  
pp. T373-T373
Author(s):  
George Iordanescu ◽  
Palamadai N. Venkatasubramanian ◽  
Jason C. Pych ◽  
Marina V. Yasvoina ◽  
Alice M. Wyrwicz
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Mouse Model ◽  
Transgenic Mouse ◽  
Amyloid Plaque ◽  
Transgenic Mouse Model ◽  
Model Of Alzheimer’S Disease ◽  
Plaque Load
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