scholarly journals Class I histone deacetylase inhibition ameliorates social cognition and cell adhesion molecule plasticity deficits in a rodent model of autism spectrum disorder

2012 ◽  
Vol 63 (4) ◽  
pp. 750-760 ◽  
Author(s):  
Andrew G. Foley ◽  
Shane Gannon ◽  
Nanette Rombach-Mullan ◽  
Alison Prendergast ◽  
Claire Barry ◽  
...  
2014 ◽  
Vol 20 (1) ◽  
pp. 23-26 ◽  
Author(s):  
Marc Woodbury-Smith

SummaryIn medical practice it is crucial that symptom descriptions are as precise and objective as possible, which psychiatry attempts to achieve through its psychopathological lexicon. The term ‘autism spectrum disorder’ has now entered psychiatric nosology, but the symptom definitions on which it is based are not robust, potentially making reliable and valid diagnoses a problem. This is further compounded by the spectral nature of the disorder and its lack of clear diagnostic boundaries. To overcome this, there is a need for a psychopathological lexicon of 'social cognition’ and a classification system that splits rather than lumps disorders with core difficulties in social interaction.


Author(s):  
Arshya Vahabzadeh ◽  
Samantha M. Landino ◽  
Beate C. Finger ◽  
William A. Carlezon ◽  
Christopher J. McDougle

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