24S-Hydroxycholesterol enhances synaptic vesicle cycling in the mouse neuromuscular junction: Implication of glutamate NMDA receptors and nitric oxide

2017 ◽  
Vol 117 ◽  
pp. 61-73 ◽  
Author(s):  
M.R. Kasimov ◽  
M.R. Fatkhrakhmanova ◽  
K.A. Mukhutdinova ◽  
A.M. Petrov
Keyword(s):  
Nitric Oxide ◽  
Neuromuscular Junction ◽  
Nmda Receptors ◽  
Synaptic Vesicle ◽  
Vesicle Cycling ◽  
Glutamate Nmda Receptors

Agmatine attenuates reserpine-induced oral dyskinesia in mice: Role of oxidative stress, nitric oxide and glutamate NMDA receptors

2016 ◽  
Vol 312 ◽  
pp. 64-76 ◽  
Author(s):  
Andréia S. Cunha ◽  
Filipe C. Matheus ◽  
Morgana Moretti ◽  
Tuane B. Sampaio ◽  
Anicleto Poli ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Nitric Oxide ◽  
Nmda Receptors ◽  
Oral Dyskinesia ◽  
Glutamate Nmda Receptors

Role of glutamate NMDA receptors and nitric oxide located within the periaqueductal gray on defensive behaviors in mice confronted by predator

2009 ◽  
Vol 204 (4) ◽  
pp. 617-625 ◽  
Author(s):  
Eduardo F. Carvalho-Netto ◽  
Karina S. Gomes ◽  
Vanessa C. S. Amaral ◽  
Ricardo L. Nunes-de-Souza
Keyword(s):  
Nitric Oxide ◽  
Nmda Receptors ◽  
Periaqueductal Gray ◽  
Defensive Behaviors ◽  
Glutamate Nmda Receptors

scholarly journals Clathrin Dependence of Synaptic-Vesicle Formation at the Drosophila Neuromuscular Junction

2008 ◽  
Vol 18 (6) ◽  
pp. 401-409 ◽  
Author(s):  
Heather Heerssen ◽  
Richard D. Fetter ◽  
Graeme W. Davis
Keyword(s):  
Neuromuscular Junction ◽  
Synaptic Vesicle ◽  
Vesicle Formation

Spatial variability in release at the frog neuromuscular junction measured with FM1-43

1999 ◽  
Vol 77 (9) ◽  
pp. 672-678 ◽  
Author(s):  
L -G Wu ◽  
W J Betz
Keyword(s):  
Neuromuscular Junction ◽  
Spatial Variability ◽  
Synaptic Vesicle ◽  
Motor Nerve ◽  
Frog Neuromuscular Junction ◽  
Electron Microscopic ◽  
Electrical Nerve Stimulation ◽  
Large Vesicle ◽  
Fluorescence And Electron Microscopy ◽  
Alpha Bungarotoxin

We quantified the spatial variability in release properties at different synaptic vesicle clusters in frog motor nerve terminals, using a combination of fluorescence and electron microscopy. Individual synaptic vesicle clusters labeled with FM1-43 varied more than 10-fold in initial intensity (integrated FM1-43 fluorescence) and in absolute rate of dye loss during tetanic electrical nerve stimulation. Most of this variability arose because large vesicle clusters spanned more than one presynaptic active zone (inferred from postsynaptic acetylcholine receptor stripes labeled with rhodamine-conjugated alpha-bungarotoxin); when the rate of dye loss was normalized to the length of receptor stripe covered, variability from spot to spot was greatly reduced. In addition, electron microscopic measurements showed that large vesicle clusters (i.e., those spanning multiple active zones) were also thicker, and the increased depth of vesicles led to increased total spot fluorescence without a corresponding increase in the rate of dye loss during stimulation. These results did not reveal the presence of "hot zones" of secretory activity.Key words: synaptic transmission, exocytosis, synaptic vesicles, neuromuscular junction.

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