Crucial role of PACAP in neural progenitor cells during development and after degeneration

Neuropeptides ◽  
2017 ◽  
Vol 65 ◽  
pp. 142-143
Author(s):  
Jun Watanabe ◽  
Hirokazu Ohtaki ◽  
Tomoya Nakamachi ◽  
Minako Matsumoto ◽  
Shun Sasaki ◽  
...  
Keyword(s):  
Progenitor Cells ◽  
Crucial Role ◽  
Neural Progenitor Cells ◽  
Neural Progenitor

A Role of CPEB1 in the Modulation of Proliferation and Neuronal Maturation of Rat Primary Neural Progenitor Cells

2013 ◽  
Vol 38 (9) ◽  
pp. 1960-1972 ◽  
Author(s):  
Ki Chan Kim ◽  
Ji-Woon Kim ◽  
Chang Soon Choi ◽  
Sun Young Han ◽  
Jae Hoon Cheong ◽  
...  
Keyword(s):  
Progenitor Cells ◽  
Neural Progenitor Cells ◽  
Neural Progenitor ◽  
Neuronal Maturation

scholarly journals White matter tracts for the trafficking of neural progenitor cells characterized by cellular MRI and immunohistology: the role of CXCL12/CXCR4 signaling

2014 ◽  
Vol 220 (4) ◽  
pp. 2073-2085 ◽  
Author(s):  
Chiao-Chi V. Chen ◽  
Yi-Hua Hsu ◽  
D. M. Jayaseema ◽  
Jeou-Yuan Joanne Chen ◽  
Dueng-Yuan Hueng ◽  
...  
Keyword(s):  
White Matter ◽  
Progenitor Cells ◽  
Neural Progenitor Cells ◽  
Neural Progenitor ◽  
White Matter Tracts ◽  
Cellular Mri ◽  
Cxcr4 Signaling

scholarly journals Spinal cord organogenesis model reveals role of Flk1+ cells in self-organization of neural progenitor cells into complex spinal cord tissue

2018 ◽  
Vol 33 ◽  
pp. 156-165 ◽  
Author(s):  
Baohan Pan ◽  
Hushan Ao ◽  
Su Liu ◽  
Yuming Xu ◽  
John W. McDonald ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Progenitor Cells ◽  
Neural Progenitor Cells ◽  
Neural Progenitor ◽  
Self Organization ◽  
Spinal Cord Tissue

Role of MAPKs in Low Level Methylmercury Induced Proliferation Inhibition of Neural Progenitor Cells

Epidemiology ◽  
2011 ◽  
Vol 22 ◽  
pp. S72
Author(s):  
Mingyu Xu ◽  
Chonghuai Yan ◽  
Ying Tian ◽  
Xiaobing Yuan
Keyword(s):  
Progenitor Cells ◽  
Neural Progenitor Cells ◽  
Neural Progenitor ◽  
Proliferation Inhibition ◽  
Low Level

scholarly journals Characterization hiPSC-derived neural progenitor cells and neurons to investigate the role of NOS1AP isoforms in human neuron dendritogenesis

2020 ◽  
Vol 109 ◽  
pp. 103562
Author(s):  
Christen M. Crosta ◽  
Kristina Hernandez ◽  
Atul K. Bhattiprolu ◽  
Allen Y. Fu ◽  
Jennifer C. Moore ◽  
...  
Keyword(s):  
Progenitor Cells ◽  
Neural Progenitor Cells ◽  
Neural Progenitor ◽  
Human Neuron

scholarly journals Essential role of proteasomes in maintaining self-renewal in neural progenitor cells

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Yunhe Zhao ◽  
Xueqin Liu ◽  
Zebin He ◽  
Xiaojie Niu ◽  
Weijun Shi ◽  
...  
Keyword(s):  
Progenitor Cells ◽  
Essential Role ◽  
Neural Progenitor Cells ◽  
Neural Progenitor ◽  
Self Renewal

scholarly journals Dual Role of Rbpj in the Maintenance of Neural Progenitor Cells and Neuronal Migration in Cortical Development

2020 ◽  
Vol 30 (12) ◽  
pp. 6444-6457
Author(s):  
Alexander I Son ◽  
Shahid Mohammad ◽  
Toru Sasaki ◽  
Seiji Ishii ◽  
Satoshi Yamashita ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Notch Signaling ◽  
Progenitor Cells ◽  
Knockout Mice ◽  
Neural Progenitor Cells ◽  
Cortical Development ◽  
Neural Progenitor ◽  
Dual Role

Abstract The development of the cerebral cortex is directed by a series of methodically precise events, including progenitor cell proliferation, neural differentiation, and cell positioning. Over the past decade, many studies have demonstrated the critical contributions of Notch signaling in neurogenesis, including that in the developing telencephalon. However, in vivo evidence for the role of Notch signaling in cortical development still remains limited partly due to the redundant functions of four mammalian Notch paralogues and embryonic lethality of the knockout mice. Here, we utilized the conditional deletion and in vivo gene manipulation of Rbpj, a transcription factor that mediates signaling by all four Notch receptors, to overcome these challenges and examined the specific roles of Rbpj in cortical development. We report severe structural abnormalities in the embryonic and postnatal cerebral cortex in Rbpj conditional knockout mice, which provide strong in vivo corroboration of previously reported functions of Notch signaling in neural development. Our results also provide evidence for a novel dual role of Rbpj in cell type-specific regulation of two key developmental events in the cerebral cortex: the maintenance of the undifferentiated state of neural progenitor cells, and the radial and tangential allocation of neurons, possibly through stage-dependent differential regulation of Ngn1.

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