The relationship between fish consumption and the risk of developing acute coronary syndromes among smokers: The CARDIO2000 case-control study

2005 ◽  
Vol 15 (6) ◽  
pp. 402-409 ◽  
Author(s):  
Demosthenes B. Panagiotakos ◽  
Christos Pitsavos ◽  
Antonis Zampelas ◽  
Christina Chrysohoou ◽  
Christodoulos Stefanadis
2008 ◽  
Vol 7 (1_suppl) ◽  
pp. 11-12
Author(s):  
Evaggelia Gerodimou ◽  
Maria Salourou ◽  
Dimitra Dedemadi ◽  
Theodora Mihalopoulou ◽  
Eleftherios Tsiamis ◽  
...  

1997 ◽  
Vol 77 (06) ◽  
pp. 1179-1181 ◽  
Author(s):  
Stefan-Martin Herrmann ◽  
Odette Poirier ◽  
Pedro Marques-Vidal ◽  
Alun Evans ◽  
Dominique Arveiler ◽  
...  

SummaryThe GPIIb/IIIa receptor complex may contribute to acute coronary syndromes by mediating platelet aggregation. The Leu33/Pro polymorphism (PlAl/PlA2) of the GPIIIa has recently been shown to be associated with CHD in a small case-control study. We have investigated this polymorphism in a large multicenter study of patients with myocardial infarction and controls and found no difference in the distribution of allele and genotype frequencies between cases and controls.


2003 ◽  
Vol 133 (10) ◽  
pp. 3228-3232 ◽  
Author(s):  
Demosthenes B. Panagiotakos ◽  
Christos Pitsavos ◽  
Christina Chrysohoou ◽  
Peter Kokkinos ◽  
Pavlos Toutouzas ◽  
...  

2020 ◽  
Author(s):  
Li Shen ◽  
Tianlun Yang ◽  
Ke Xia ◽  
Zhiqiang Yan ◽  
Juanjuan Tan ◽  
...  

Abstract Background: Platelet activation plays a crucial role in the pathogenesis of coronary artery disease (CAD).Platelet P-selectin (CD62P) is a platelet classic activation indicator on the platelet surface,and soluble TREM-like transcript-1 (sTLT-1) is a new indicator;hpwever, the relationship between these two markers and CAD(especially in acute coronary syndromes (ACS) has not been elucidated. This study aimed to investigate the expression of CD62Pon the platelet surface and sTLT-1 in serum and to assess their relationship with CAD.Methods: We measured the levels of CD62P and sTLT-1 in 83 patients with CAD compared to 49 controls. The associations with age, blood pressure, lipid profiles, body mass index and liver injury marker levels were also examined.Results: A stepwise increase in CD62P concentration was found based on the number of CAD patients (P <0.01), especially in Acute myocaedial infarction( AMI) patients (P <0.01). Serum sTLT-1 concentration in the AMI and Unstable angina pectoris(UAP) groups was higher than that in the Normal control (NC) group (P <0.01).Conclusions: The consistency of sTLT-1 and CD62P expression levels in CAD indicates that the sTLT-1 level may be a new marker of platelet activation and is positively related to CAD.


2007 ◽  
Vol 62 (2) ◽  
pp. 171-177 ◽  
Author(s):  
M D Kontogianni ◽  
D B Panagiotakos ◽  
C Pitsavos ◽  
C Chrysohoou ◽  
C Stefanadis

2020 ◽  
Author(s):  
Li Shen ◽  
Tianlun Yang ◽  
Ke Xia ◽  
Zhiqiang Yan ◽  
Juanjuan Tan ◽  
...  

Abstract Background/Aims: Platelet activation plays a crucial role in the pathogenesis of coronary artery disease(CAD) , platelet P-selectin(CD62P )is a platelet classic activation indicator in platelet surface and soluble TREM-like transcript-1 (sTLT-1) is a new one,the relation between these two makers and acute coronary syndromes(ACS) has not been elucidated. This study aimed to investigate the expression of CD62P in platelet surface and sTLT-1 on serum and their relationship with CAD. Methods: We measured the levels of CD62P and sTLT-1 in 83 patients undergoing CAD compared to 49 controls.The associations with age, blood pressure,lipid profiles, body mass index and liver injury marker levels were also examined. Results: A stepwise increase in CD62P concentration was found based on the number of CAD patients (P <0.01), especially in AMI (P <0.01) . Serum sTLT-1 concentration of AMI and UAP were more higher than the NC group (P <0.01). Conclusions: The consistent of sTLT-1 and CD62P expression levels in CAD,indicating that sTLT-1 level may be a new maker of platelet activating and positively related with CAD.


2002 ◽  
Vol 13 (5) ◽  
pp. 295-300 ◽  
Author(s):  
Christos Pitsavos ◽  
Demosthenes B. Panagiotakos ◽  
Christina Chrysohoou ◽  
John Skoumas ◽  
Ioanna Papaioannou ◽  
...  

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