The Leu33/Pro Polymorphism (PIA1/PIA2 ) of the Glycoprotein IIIa (GPIIIa) Receptor Is Not Related to Myocardial Infarction in the ECTIM Study

1997 ◽  
Vol 77 (06) ◽  
pp. 1179-1181 ◽  
Author(s):  
Stefan-Martin Herrmann ◽  
Odette Poirier ◽  
Pedro Marques-Vidal ◽  
Alun Evans ◽  
Dominique Arveiler ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Coronary Syndromes ◽  
Case Control Study ◽  
Case Control ◽  
Receptor Complex ◽  
Genotype Frequencies ◽  
Large Multicenter Study ◽  
Glycoprotein Iiia ◽  
Coronary Syndromes ◽  
Control Study

SummaryThe GPIIb/IIIa receptor complex may contribute to acute coronary syndromes by mediating platelet aggregation. The Leu33/Pro polymorphism (PlAl/PlA2) of the GPIIIa has recently been shown to be associated with CHD in a small case-control study. We have investigated this polymorphism in a large multicenter study of patients with myocardial infarction and controls and found no difference in the distribution of allele and genotype frequencies between cases and controls.

1317 Fish consumption and the risk of developing acute coronary syndromes: A case-control study

2008 ◽  
Vol 7 (1_suppl) ◽  
pp. 11-12
Author(s):  
Evaggelia Gerodimou ◽  
Maria Salourou ◽  
Dimitra Dedemadi ◽  
Theodora Mihalopoulou ◽  
Eleftherios Tsiamis ◽  
...  
Keyword(s):  
Fish Consumption ◽  
Acute Coronary Syndromes ◽  
Case Control Study ◽  
Case Control ◽  
Coronary Syndromes ◽  
Control Study

The relationship between fish consumption and the risk of developing acute coronary syndromes among smokers: The CARDIO2000 case-control study

2005 ◽  
Vol 15 (6) ◽  
pp. 402-409 ◽  
Author(s):  
Demosthenes B. Panagiotakos ◽  
Christos Pitsavos ◽  
Antonis Zampelas ◽  
Christina Chrysohoou ◽  
Christodoulos Stefanadis
Keyword(s):  
Fish Consumption ◽  
Acute Coronary Syndromes ◽  
Case Control Study ◽  
Case Control ◽  
Coronary Syndromes ◽  
The Relationship ◽  
Control Study

scholarly journals The J-Shaped Effect of Coffee Consumption on the Risk of Developing Acute Coronary Syndromes: The CARDIO2000 Case-Control Study

2003 ◽  
Vol 133 (10) ◽  
pp. 3228-3232 ◽  
Author(s):  
Demosthenes B. Panagiotakos ◽  
Christos Pitsavos ◽  
Christina Chrysohoou ◽  
Peter Kokkinos ◽  
Pavlos Toutouzas ◽  
...  
Keyword(s):  
Acute Coronary Syndromes ◽  
Case Control Study ◽  
Coffee Consumption ◽  
Case Control ◽  
Coronary Syndromes ◽  
Control Study

scholarly journals Relationship between meat intake and the development of acute coronary syndromes: the CARDIO2000 case–control study

2007 ◽  
Vol 62 (2) ◽  
pp. 171-177 ◽  
Author(s):  
M D Kontogianni ◽  
D B Panagiotakos ◽  
C Pitsavos ◽  
C Chrysohoou ◽  
C Stefanadis
Keyword(s):  
Acute Coronary Syndromes ◽  
Case Control Study ◽  
Case Control ◽  
Meat Intake ◽  
Coronary Syndromes ◽  
Control Study

scholarly journals P-selectin(CD62P) and soluble TREM-like transcript-1(sTLT-1) are associated with coronary artery disease-A case control study

2020 ◽  
Author(s):  
Li Shen ◽  
Tianlun Yang ◽  
Ke Xia ◽  
Zhiqiang Yan ◽  
Juanjuan Tan ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Acute Coronary Syndromes ◽  
Case Control Study ◽  
Case Control ◽  
Platelet Surface ◽  
Coronary Syndromes ◽  
Artery Disease ◽  
Control Study

Abstract Background/Aims: Platelet activation plays a crucial role in the pathogenesis of coronary artery disease(CAD) ， platelet P-selectin(CD62P )is a platelet classic activation indicator in platelet surface and soluble TREM-like transcript-1 (sTLT-1) is a new one,the relation between these two makers and acute coronary syndromes(ACS) has not been elucidated. This study aimed to investigate the expression of CD62P in platelet surface and sTLT-1 on serum and their relationship with CAD. Methods: We measured the levels of CD62P and sTLT-1 in 83 patients undergoing CAD compared to 49 controls.The associations with age, blood pressure,lipid profiles, body mass index and liver injury marker levels were also examined. Results: A stepwise increase in CD62P concentration was found based on the number of CAD patients (P <0.01), especially in AMI (P <0.01) . Serum sTLT-1 concentration of AMI and UAP were more higher than the NC group (P <0.01). Conclusions: The consistent of sTLT-1 and CD62P expression levels in CAD,indicating that sTLT-1 level may be a new maker of platelet activating and positively related with CAD.

The effect of Mediterranean diet on the risk of the development of acute coronary syndromes in hypercholesterolemic people: a case–control study (CARDIO2000)

2002 ◽  
Vol 13 (5) ◽  
pp. 295-300 ◽  
Author(s):  
Christos Pitsavos ◽  
Demosthenes B. Panagiotakos ◽  
Christina Chrysohoou ◽  
John Skoumas ◽  
Ioanna Papaioannou ◽  
...  
Keyword(s):  
Mediterranean Diet ◽  
Acute Coronary Syndromes ◽  
Case Control Study ◽  
Case Control ◽  
Coronary Syndromes ◽  
Control Study

scholarly journals Chlamydial bacteriophage: No Role in Acute Coronary Events?

2005 ◽  
Vol 16 (5) ◽  
pp. 298-300
Author(s):  
David M Patrick ◽  
Karuna Karunakaran ◽  
Adrian R Levy ◽  
Kenneth Gin ◽  
Valencia Remple ◽  
...  
Keyword(s):  
Acute Coronary Syndromes ◽  
Case Control Study ◽  
Case Control ◽  
Coronary Risk Factors ◽  
Coronary Risk ◽  
Vp1 Protein ◽  
Coronary Syndromes ◽  
Coronary Events ◽  
And Control ◽  
Control Study

BACKGROUND: A relationship betweenChlamydia pneumoniae infection and acute coronary syndromes has not been consistently found in published studies. It has been hypothesized that a bacteriophage-infected subset ofC pneumoniaemay be uniquely equipped to promote atherosclerosis and acute coronary syndromes through the expression of phage genes. METHODS: The authors performed a pilot case-control study of acute coronary events. Case and control subjects were characterized demographically and according to recognized coronary risk factors. These subjects also provided serum for the detection of antibody to the elementary bodies ofC pneumoniaeand antibody to the Vp1 protein coded by the phage. Bivariate and multivariate comparisons were performed using statistics appropriate for paired analyses. RESULTS: Antibodies toC pneumoniae, Vp1 protein or both were not associated with acute coronary events by bivariate or multivariate analysis. As expected, case subjects were significantly more likely to have hypertension, hypercholesterolemia or diabetes mellitus. CONCLUSION: The present study adds to a growing body of literature that does not support the hypothesized relationship betweenC pneumoniae(or a phage-infected subset ofC pneumoniae) and acute coronary syndromes.

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