Effects of intermittent parathyroid hormone treatment on new bone formation during distraction osteogenesis in the rat mandible

2012 ◽  
Vol 114 (1) ◽  
pp. e36-e42 ◽  
Author(s):  
Mir Nowazesh Ali ◽  
Tadaharu Kobayashi ◽  
Mikako Tanaka ◽  
Hayato Ohshima ◽  
Sadakazu Ejiri ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Bone Formation ◽  
Distraction Osteogenesis ◽  
Hormone Treatment ◽  
New Bone Formation ◽  
Rat Mandible

The evaluation of the effects of hyperbaric oxygen therapy on new bone formation obtained by distraction osteogenesis in terms of consolidation periods

2011 ◽  
Vol 16 (5) ◽  
pp. 1363-1370 ◽  
Author(s):  
Ibrahim Mutlu ◽  
Yavuz Sinan Aydintug ◽  
Ayper Kaya ◽  
Gurkan Rasit Bayar ◽  
Berkay Tolga Suer ◽  
...  
Keyword(s):  
Bone Formation ◽  
Hyperbaric Oxygen ◽  
Distraction Osteogenesis ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
New Bone Formation

Ultrasonographic Assessment of New Bone Formation in Maxillary Distraction Osteogenesis

2008 ◽  
Vol 66 (8) ◽  
pp. 1750-1753 ◽  
Author(s):  
Kana Mukai-Higashihori ◽  
Yoshiyuki Baba ◽  
Akemi Tetsumura ◽  
Michiko Tsuji ◽  
Takashi Ishizaki ◽  
...  
Keyword(s):  
Bone Formation ◽  
Distraction Osteogenesis ◽  
New Bone Formation ◽  
Ultrasonographic Assessment ◽  
Maxillary Distraction

scholarly journals Bone remodeling effect of a chitosan and calcium phosphate-based composite

2019 ◽  
Vol 6 (4) ◽  
pp. 241-247 ◽  
Author(s):  
Lilja Kjalarsdóttir ◽  
Arna Dýrfjörd ◽  
Atli Dagbjartsson ◽  
Elín H Laxdal ◽  
Gissur Örlygsson ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Formation ◽  
Bone Remodeling ◽  
Morphological Changes ◽  
Drill Hole ◽  
New Bone Formation ◽  
Sprague Dawley ◽  
Time Points ◽  
Formation Pattern ◽  
Rat Mandible

Abstract Chitosan is a biocompatible polymer that has been widely studied for tissue engineering purposes. The aim of this research was to assess bone regenerative properties of an injectable chitosan and calcium phosphate-based composite and identify optimal degree of deacetylation (%DDA) of the chitosan polymer. Drill holes were generated on the left side of a mandible in Sprague-Dawley rats, and the hole was either left empty or filled with the implant. The animals were sacrificed at several time points after surgery (7–22 days) and bone was investigated using micro-CT and histology. No significant new bone formation was observed in the implants themselves at any time points. However, substantial new bone formation was observed in the rat mandible further away from the drill hole. Morphological changes indicating bone formation were found in specimens explanted on Day 7 in animals that received implant. Similar bone formation pattern was seen in control animals with an empty drill hole at later time points but not to the same extent. A second experiment was performed to examine if the %DDA of the chitosan polymer influenced the bone remodeling response. The results suggest that chitosan polymers with %DDA between 50 and 70% enhance the natural bone remodeling mechanism.

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