Immunohistochemical analysis of cytokeratins of gingival cyst of adult: phenotypic similarity with ducts of salivary glands

2012 ◽  
Vol 114 (4) ◽  
pp. e117-e118
Keyword(s):  
Salivary Glands ◽  
Immunohistochemical Analysis ◽  
Phenotypic Similarity

scholarly journals Common immunophenotypic features of submandibular salivary glands and thymus in rats

2012 ◽  
Vol 140 (5-6) ◽  
pp. 270-277
Author(s):  
Ivan Dozic ◽  
Tatjana Todorovic ◽  
Miodrag Colic
Keyword(s):  
Salivary Gland ◽  
Epithelial Cells ◽  
Salivary Glands ◽  
Endocrine System ◽  
Immunohistochemical Analysis ◽  
The Body ◽  
Thymic Epithelial Cells ◽  
Submandibular Salivary Gland ◽  
Phenotypic Similarity ◽  
Submandibular Salivary Glands

Introduction. Submandibular salivary gland is a part of the neuro-immune-endocrine system. It contains biological factors which regulate a number of functions in the body including the modulation of thymus function. Objective. The aim of the study was to investigate immunophenotypic characteristics of submandibular salivary glands of rats during ontogenesis, using the panels of monoclonal antibodies and to compare with the phenotypic characteristics of epithelial components of the thymus. Methods. Submandibular salivary glands and thymus were obtained from 1, 30 and 60 days old male AO (Albino, Oxford) rats. Streptavidin-biotin peroxidase method was used for staining. Results. Immunohistochemical analysis of rat submandibular salivary glands showed phenotypic heterogeneity of particular components of this gland during the postnatal development. We demonstrated that rat submandibular salivary glands share common antigens with rat thymic epithelial cells, but the observed phenotypic similarity between the individual regions was considered much more significant. Our data showed that the phenotypic similarity between duct epithelial cells and subcapsular epithelial cells and most medullary cells, whereas cortical epithelial cells are phenotypically similar to acinar cells. Conclusion. This immunohistological study showed phenotypic complexity of the submandibular salivary gland and similarity to the thymus that opens new perspectives in studying phenotypic similarities between this gland and lymphatic organs.

scholarly journals SGLT1 protein expression in plasma membrane of acinar cells correlates with the sympathetic outflow to salivary glands in diabetic and hypertensive rats

2010 ◽  
Vol 299 (6) ◽  
pp. E1028-E1037 ◽  
Author(s):  
Robinson Sabino-Silva ◽  
Ana B. T. Alves-Wagner ◽  
Katia Burgi ◽  
Maristela M. Okamoto ◽  
Adilson S. Alves ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Salivary Glands ◽  
Sympathetic Activity ◽  
Basolateral Membrane ◽  
Acinar Cells ◽  
Immunohistochemical Analysis ◽  
Spontaneously Hypertensive ◽  
Sodium Glucose Cotransporter ◽  
Wistar Kyoto ◽  
Induced Changes

Salivary gland dysfunction is a feature in diabetes and hypertension. We hypothesized that sodium-glucose cotransporter 1 (SGLT1) participates in salivary dysfunctions through a sympathetic- and protein kinase A (PKA)-mediated pathway. In Wistar-Kyoto (WKY), diabetic WKY (WKY-D), spontaneously hypertensive (SHR), and diabetic SHR (SHR-D) rats, PKA/SGLT1 proteins were analyzed in parotid and submandibular glands, and the sympathetic nerve activity (SNA) to the glands was monitored. Basal SNA was threefold higher in SHR ( P < 0.001 vs. WKY), and diabetes decreased this activity (∼50%, P < 0.05) in both WKY and SHR. The catalytic subunit of PKA and the plasma membrane SGLT1 content in acinar cells were regulated in parallel to the SNA. Electrical stimulation of the sympathetic branch to salivary glands increased (∼30%, P < 0.05) PKA and SGLT1 expression. Immunohistochemical analysis confirmed the observed regulations of SGLT1, revealing its location in basolateral membrane of acinar cells. Taken together, our results show highly coordinated regulation of sympathetic activity upon PKA activity and plasma membrane SGLT1 content in salivary glands. Furthermore, the present findings show that diabetic- and/or hypertensive-induced changes in the sympathetic activity correlate with changes in SGLT1 expression in basolateral membrane of acinar cells, which can participate in the salivary glands dysfunctions reported by patients with these pathologies.

scholarly journals Solitary Fibrous Tumor of the Auditory Canal

2004 ◽  
Vol 128 (12) ◽  
pp. e169-e171 ◽  
Author(s):  
Sherif Rezk ◽  
Mohammad Yousef ◽  
Marshall Zamansky ◽  
Ashraf Khan
Keyword(s):  
Salivary Glands ◽  
Solitary Fibrous Tumor ◽  
Paranasal Sinuses ◽  
Spindle Cell ◽  
Immunohistochemical Analysis ◽  
Spindle Cell Neoplasm ◽  
Cell Neoplasm ◽  
Fibrous Tumor

Abstract Solitary fibrous tumor (SFT) is an uncommon spindle cell neoplasm of increasing incidence that was originally described to be of pleural origin; however, more recently, SFT has been reported in extrapleural sites, including the orbit, liver, salivary glands, tongue, nose, paranasal sinuses, larynx, retroperitoneum, meninges, and thyroid. The increase in the number of SFTs does not necessarily mean increased incidence of this tumor but rather an increased understanding of this tumor, especially recognition of this tumor in extrapleural locations, which has been aided by immunohistochemical analysis. We report a case of SFT in the auditory canal, which to our knowledge has not been previously reported, as evident by morphologic findings and immunophenotype.

scholarly journals Myoepithelioma of Soft Palate: A Case Report and Review of Literature

2016 ◽  
Vol 8 (1) ◽  
pp. 32-34
Author(s):  
HS Bhuie ◽  
Navneet Mathur ◽  
Arjun N Yogee ◽  
Raman Choudhary
Keyword(s):  
Case Report ◽  
Salivary Glands ◽  
Soft Palate ◽  
Immunohistochemical Analysis ◽  
Final Diagnosis ◽  
Histological Feature ◽  
Benign Neoplasms ◽  
Review Of Literature ◽  
Minor Salivary Glands ◽  
Review Of The Literature

ABSTRACT Myoepitheliomas are rare benign neoplasms of salivary glands representing less than 1% of all salivary gland tumors. This tumor is usually located in the parotid gland and less frequently in the submandibular gland and minor salivary glands that are distributed throughout the oral cavity. Diagnosis of tumor is based on evaluation of histological feature, although immunohistochemical analysis confirms the myoepithelial origin of tumor cells and the final diagnosis. Herein, a case of plasmacytoid myoepithelioma of soft palate in an adult male is presented along with review of the literature. How to cite this article Yogee AN, Choudhary R, Mathur N, Bhuie HS. Myoepithelioma of Soft Palate: A Case Report and Review of Literature. Int J Otorhinolaryngol Clin 2016;8(1):32-34.

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