Super-resolution photoacoustic imaging based on saturation difference of transient absorption

2022 ◽  
Vol 150 ◽  
pp. 106877
Author(s):  
Xinli Jiang ◽  
Zhongjiang Chen ◽  
Da Xing
Keyword(s):  
Transient Absorption ◽  
Photoacoustic Imaging ◽  
Super Resolution ◽  
Saturation Difference

scholarly journals Ultrasound and Photoacoustic Imaging of Laser-Activated Phase-Change Perfluorocarbon Nanodroplets

Photonics ◽  
2021 ◽  
Vol 8 (10) ◽  
pp. 405
Author(s):  
Heechul Yoon
Keyword(s):  
Phase Change ◽  
Photoacoustic Imaging ◽  
Super Resolution ◽  
Optical Pulses ◽  
Future Directions ◽  
Therapeutic Drugs ◽  
Contrast Enhanced ◽  
Resolution Imaging ◽  
Optical Activation ◽  
Micrometer Size

Laser-activated perfluorocarbon nanodroplets (PFCnDs) are emerging phase-change contrast agents that showed promising potential in ultrasound and photoacoustic (US/PA) imaging. Unlike monophase gaseous microbubbles, PFCnDs shift their state from liquid to gas via optical activation and can provide high US/PA contrast on demand. Depending on the choice of perfluorocarbon core, the vaporization and condensation dynamics of the PFCnDs are controllable. Therefore, these configurable properties of activation and deactivation of PFCnDs are employed to enable various imaging approaches, including contrast-enhanced imaging and super-resolution imaging. In addition, synchronous application of both acoustic and optical pulses showed a promising outcome vaporizing PFCnDs with lower activation thresholds. Furthermore, due to their sub-micrometer size, PFCnDs can be used for molecular imaging of extravascular tissue. PFCnDs can also be an effective therapeutic tool. As PFCnDs can carry therapeutic drugs or other particles, they can be used for drug delivery, as well as photothermal and photodynamic therapies. Blood barrier opening for neurological applications was recently demonstrated with optically-triggered PFCnDs. This paper specifically focuses on the activation and deactivation properties of laser-activated PFCnDs and associated US/PA imaging approaches, and briefly discusses their theranostic potential and future directions.

Super-resolution approaches in photoacoustic imaging

2019 ◽  
Vol 145 (3) ◽  
pp. 1779-1779 ◽  
Author(s):  
Bastien Arnal ◽  
Sergey Vilov ◽  
Guillaume Godefroy ◽  
Emmanuel Bossy
Keyword(s):  
Photoacoustic Imaging ◽  
Super Resolution

scholarly journals Label-Free Super-Resolution Microscopy By Means of Transient Absorption Saturation

2021 ◽  
Vol 120 (3) ◽  
pp. 181a
Author(s):  
Behjat Sadat Kariman ◽  
Takahiro Deguchi ◽  
Marco Scotto d'Abbusco ◽  
Giulia Zanini ◽  
Alberto Diaspro ◽  
...  
Keyword(s):  
Transient Absorption ◽  
Super Resolution ◽  
Label Free ◽  
Absorption Saturation ◽  
Super Resolution Microscopy

Fluctuation-based Super-resolution Photoacoustic Imaging

2018 ◽  
Author(s):  
Sergey Vilov ◽  
Bastien Arnal ◽  
Thomas Chaigne ◽  
Ori Katz ◽  
Emmanuel Bossy
Keyword(s):  
Photoacoustic Imaging ◽  
Super Resolution

scholarly journals Autoencoder based blind source separation for photoacoustic resolution enhancement

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Matan Benyamin ◽  
Hadar Genish ◽  
Ran Califa ◽  
Lauren Wolbromsky ◽  
Michal Ganani ◽  
...  
Keyword(s):  
Photoacoustic Imaging ◽  
Resolution Enhancement ◽  
Super Resolution ◽  
Optical Excitation ◽  
Biological Tissues ◽  
General Idea ◽  
Acoustic Response ◽  
Depth Imaging ◽  
Resolution Imaging ◽  
Novel Concept

AbstractPhotoacoustics is a promising technique for in-depth imaging of biological tissues. However, the lateral resolution of photoacoustic imaging is limited by size of the optical excitation spot, and therefore by light diffraction and scattering. Several super-resolution approaches, among which methods based on localization of labels and particles, have been suggested, presenting promising but limited solutions. This work demonstrates a novel concept for extended-resolution imaging based on separation and localization of multiple sub-pixel absorbers, each characterized by a distinct acoustic response. Sparse autoencoder algorithm is used to blindly decompose the acoustic signal into its various sources and resolve sub-pixel features. This method can be used independently or as a combination with other super-resolution techniques to gain further resolution enhancement and may also be extended to other imaging schemes. In this paper, the general idea is presented in details and experimentally demonstrated.

scholarly journals Super-resolution photoacoustic imaging through a scattering wall

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Donald B. Conkey ◽  
Antonio M. Caravaca-Aguirre ◽  
Jake D. Dove ◽  
Hengyi Ju ◽  
Todd W. Murray ◽  
...  
Keyword(s):  
Photoacoustic Imaging ◽  
Super Resolution

scholarly journals Far-field transient absorption nanoscopy with sub-50  nm optical super-resolution

Optica ◽  
2020 ◽  
Vol 7 (10) ◽  
pp. 1402
Author(s):  
Yali Bi ◽  
Chi Yang ◽  
Lei Tong ◽  
Haozheng Li ◽  
Boyu Yu ◽  
...  
Keyword(s):  
Transient Absorption ◽  
Super Resolution ◽  
Far Field

scholarly journals Super-resolution photoacoustic imaging via flow-induced absorption fluctuations

Optica ◽  
2017 ◽  
Vol 4 (11) ◽  
pp. 1397 ◽  
Author(s):  
Thomas Chaigne ◽  
Bastien Arnal ◽  
Sergey Vilov ◽  
Emmanuel Bossy ◽  
Ori Katz
Keyword(s):  
Photoacoustic Imaging ◽  
Super Resolution ◽  
Induced Absorption

Super-resolution photoacoustic imaging of single gold nanoparticles

2016 ◽  
Author(s):  
Seunghyun Lee ◽  
Owoong Kwon ◽  
Mansik Jeon ◽  
Jaejung Song ◽  
Minguk Jo ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Photoacoustic Imaging ◽  
Super Resolution
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