Chorda Tympani in Chronic Inflammatory Middle Ear Disease

Objective To study the effect of chronic inflammatory middle ear disease on gustatory function of chorda tympani nerve. Methods A prospective study was performed in 2007 on 85 patients of unilateral chronic inflammatory middle ear disease of both cholesteatomatous and noncholesteatomatous type. Gustatory assessment on both sides of the tongue was performed using dry taste strips. Taste strips were made of filter paper soaked in four different taste solutions of four different concentrations each and dried. The taste score is the number of correctly identified taste strips. Results were analyzed using Analysis of Variance (ANOVA) and t-test. Results Comparison of mean taste scores on the side of diseased ear with normal ear was done. On the diseased side, the mean taste score was 9.16 and on the normal side, the mean taste score was 13.24. The difference between the two was found to be statistically significant (p<0.0001). The results were also analyzed for various other parameters like type, duration, and location of disease. Site of cholesteatoma was found to have a significant effect on the taste score of the diseased side. Patients having postero-superior retraction pocket cholesteatoma had significantly lower taste scores as compared to those having cholesteatoma at other sites (p=0.008). Conclusions A patient of chronic inflammatory middle ear disease already has dysfunctional chorda tympani and is unlikely to notice a change in the taste sensation in the event of cutting of the nerve during the course of an ear surgery.

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Chorda tympani in chronic inflammatory middle ear disease

Otolaryngology ◽

10.1016/j.otohns.2008.12.059 ◽

2009 ◽

Vol 140 (5) ◽

pp. 682-686 ◽

Cited By ~ 19

Author(s):

Arun Goyal ◽

P.P. Singh ◽

Gautam Dash

Keyword(s):

Middle Ear ◽

Chorda Tympani ◽

Taste Sensation ◽

Chorda Tympani Nerve ◽

Ear Surgery ◽

Normal Side ◽

Middle Ear Disease ◽

The Mean ◽

The Difference ◽

A Prospective Study

Objectives: To study the effect of chronic inflammatory middle ear disease on gustatory function of chorda tympani nerve. Methods: A prospective study was performed on 85 patients having unilateral chronic inflammatory middle ear disease of either cholesteatomatous or noncholesteatomatous type. Gustatory assessment on both sides of the tongue was performed using dry taste strips. Results: Comparison of mean taste scores on the side of diseased ear vs normal ear was done. On the diseased side the mean taste score was 9.16 and on the normal side the mean taste score was 13.24. The difference between the two was found to be statistically significant ( P < 0.0001). The results were also analyzed for various other parameters like type, duration, and location of disease. Conclusion: A patient with chronic inflammatory middle ear disease already has dysfunctional chorda tympani and is unlikely to notice a change in the taste sensation in the event of cutting of the nerve during the course of an ear surgery.

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A study of chorda tympani nerve injury and related symptoms following middle-ear surgery

The Journal of Laryngology & Otology ◽

10.1258/0022215053561657 ◽

2005 ◽

Vol 119 (3) ◽

pp. 189-192 ◽

Cited By ~ 34

Author(s):

P Gopalan ◽

M Kumar ◽

D Gupta ◽

J J Phillipps

Keyword(s):

Prospective Study ◽

Middle Ear ◽

Recovery Time ◽

Middle Ear Surgery ◽

Chorda Tympani ◽

Chorda Tympani Nerve ◽

Ear Surgery ◽

Number Of Patients ◽

Prolonged Recovery ◽

A Prospective Study

This is a prospective study that looks into the prevalence of chorda tympani nerve (CTN) injury and related symptoms following varying degrees of trauma to the nerve during three common types of middle-ear operation: myringoplasty, tympanotomy and mastoidectomy. The number of patients with CTN-related symptoms varied widely between the three groups. Increased occurrence of the nerve related symptoms and a prolonged recovery time were observed in the tympanotomy group. Stretching of the nerve produced more symptomatic cases than cutting it in the myringoplasty and mastoidectomy groups. Recovery was complete in 92 per cent of the symptomatic patients by 12 months. It is important to inform patients about the possibility of CTN injury during middle-ear operations, and it should also be emphasized that symptoms related to CTN injury can occur irrespective of the type of damage to the nerve.

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Chorda tympani nerve, may it have a role in stabilizing middle ear pressure?

Medical Hypotheses ◽

10.1016/j.mehy.2013.02.021 ◽

2013 ◽

Vol 80 (6) ◽

pp. 726-727 ◽

Cited By ~ 1

Author(s):

V. Rinaldi ◽

M. Cappadona ◽

M. Gaffuri ◽

S. Torretta ◽

L. Pignataro

Keyword(s):

Middle Ear ◽

Chorda Tympani ◽

Chorda Tympani Nerve ◽

Middle Ear Pressure

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Epistaxis as a marker for severe acute respiratory syndrome coronavirus-2 status – a prospective study

The Journal of Laryngology & Otology ◽

10.1017/s0022215120001863 ◽

2020 ◽

Vol 134 (8) ◽

pp. 717-720 ◽

Cited By ~ 1

Author(s):

MH Hussain ◽

M Mair ◽

P Rea

Keyword(s):

Severe Acute Respiratory Syndrome ◽

Prospective Study ◽

Control Group ◽

Study Group ◽

Chain Reaction ◽

Polymerase Chain Reaction Testing ◽

The Mean ◽

Polymerase Chain ◽

The Difference ◽

A Prospective Study

AbstractObjectiveTo evaluate the prevalence of severe acute respiratory syndrome coronavirus-2 infection in patients presenting with epistaxis to a tertiary otolaryngology unit.MethodsA prospective study was conducted of 40 consecutive patients presenting with epistaxis referred to our tertiary otolaryngology unit. A group of 40 age-matched controls were also included. All patients underwent real-time reverse transcriptase polymerase chain reaction testing for severe acute respiratory syndrome coronavirus-2. Symptoms of fever, cough and anosmia were noted in the study group.ResultsThe mean age was 66.5 ± 22.4 years in the study group. There were 22 males (55 per cent) and 18 females (45 per cent). The mean age in the control group was 66.3 ± 22.4 years (p = 0.935). There were six positive cases for severe acute respiratory syndrome coronavirus-2 (15 per cent) in the epistaxis group and one case (2.5 per cent) in the control group. The difference was statistically significant (p = 0.05).ConclusionEpistaxis may represent a presenting symptom of severe acute respiratory syndrome coronavirus-2 infection. This may serve as a useful additional criterion for screening patients.

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Low-Entry-Point Method for Chorda Tympani Nerve Preservation during Middle Ear Surgery

Otolaryngology ◽

10.1177/0194599812453554 ◽

2012 ◽

Vol 147 (5) ◽

pp. 972-974

Author(s):

Chien-Hao Chen ◽

Peir-Rong Chen ◽

Chia-Fone Lee ◽

Lee-Ping Hsu ◽

Yu-Fu Chou

Keyword(s):

Middle Ear ◽

Point Method ◽

Entry Point ◽

Middle Ear Surgery ◽

Chorda Tympani ◽

Chorda Tympani Nerve ◽

Ear Surgery ◽

Nerve Preservation

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Involvement of Workers in Closed and Semiclosed Institutions in Outbreaks of Acute Gastroenteritis Due to Norovirus

Viruses ◽

10.3390/v12121392 ◽

2020 ◽

Vol 12 (12) ◽

pp. 1392

Author(s):

Ignacio Parrón ◽

Irene Barrabeig ◽

Miquel Alseda ◽

Thais Cornejo-Sánchez ◽

Susana Guix ◽

...

Keyword(s):

Prospective Study ◽

Confidence Intervals ◽

Personal Hygiene ◽

Occupational Category ◽

Hygiene Measures ◽

The Mean ◽

The Difference ◽

Rate Ratios ◽

A Prospective Study ◽

Mean Cycle

Norovirus outbreaks frequently occur in closed or semiclosed institutions. Recent studies in Catalonia and various countries indicate that, during outbreaks in these institutions, norovirus is detected in between 23% and 60% of workers, and the prevalence of infection in asymptomatic workers involved in outbreaks ranges from 17% to 40%. In this work, we carried out a prospective study to investigate the involvement of workers in closed and semiclosed institutions during outbreaks. The attack rates (ARs) and the rate ratios (RRs) were calculated according to the type of transmission and occupational category. The RRs and 95% confidence intervals (CIs) between workers and users were calculated. The mean cycle of quantification (Cq) values were compared according to the genogroup and the presence of symptoms. ARs were higher in person-to-person transmission than in common vehicle outbreaks, and 38.8% of workers were symptomatic. The RR between workers and users was 0.46 (95% CI 0.41–0.52). The ARs in workers were high, particularly in workers with closer contact with users. The mean Cq was lower in patients than in asymptomatic infected persons, although the difference was only significant for genogroup I (GI). The frequency of asymptomatic infected persons suggests that personal hygiene measures should be followed by all workers in the centers affected.

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Erosion of the Incus by the Chorda Tympani Nerve from a Complex Retraction Pocket

Ear Nose & Throat Journal ◽

10.1177/014556131509400901 ◽

2015 ◽

Vol 94 (9) ◽

pp. 368-368 ◽

Cited By ~ 1

Author(s):

Ramanan Daniel ◽

Fiona Hill ◽

Timothy Price

Keyword(s):

Chorda Tympani ◽

Chorda Tympani Nerve ◽

Retraction Pocket

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Chorda tympani section decreases the cation specificity of depletion-induced sodium appetite in rats

AJP Regulatory Integrative and Comparative Physiology ◽

10.1152/ajpregu.1993.264.2.r319 ◽

1993 ◽

Vol 264 (2) ◽

pp. R319-R323 ◽

Cited By ~ 16

Author(s):

P. A. Breslin ◽

A. C. Spector ◽

H. J. Grill

Keyword(s):

Lick Rate ◽

Single Stimulus ◽

The Other ◽

Chloride Salt ◽

Chorda Tympani ◽

Chorda Tympani Nerve ◽

Diuretic Treatment ◽

Sodium Appetite ◽

The Difference ◽

Chloride Salts

Rats depleted of sodium by diuretic treatment were tested for their ability to respond selectively to NaCl after chorda tympani nerve (CTn) section (CTX). A variety of chloride salts (NaCl, KCl, NH4Cl, CaCl2) at two concentrations (0.05 and 0.3 M) were presented semirandomly to sodium-deplete rats in repeated single-stimulus trials (10 s). The responses of sodium-depleted surgical control rats (n = 8) were highly cation specific. These rats licked substantially more for both sodium stimuli than for any other chloride salt. On the other hand, the licking responses of CTX sodium-depleted rats (n = 8) were less cation selective. These rats licked NaCl and 0.05 M KCl at comparable rates. For both NaCl concentrations, CTX rats had significantly lower lick rates than controls. In addition, the difference between the lick rate for NaCl and that for the other salts was much greater for control rats than for CTX rats. Although CTn section did not entirely eliminate the high levels of responsivity to NaCl observed in the intact sodium-depleted rat, it did substantially compromise the selectivity of the behavior, which suggests that the input of the CTn is critical for taste-guided sodium specific behaviors.

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