scholarly journals Involvement of Workers in Closed and Semiclosed Institutions in Outbreaks of Acute Gastroenteritis Due to Norovirus

Viruses ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 1392
Author(s):  
Ignacio Parrón ◽  
Irene Barrabeig ◽  
Miquel Alseda ◽  
Thais Cornejo-Sánchez ◽  
Susana Guix ◽  
...  

Norovirus outbreaks frequently occur in closed or semiclosed institutions. Recent studies in Catalonia and various countries indicate that, during outbreaks in these institutions, norovirus is detected in between 23% and 60% of workers, and the prevalence of infection in asymptomatic workers involved in outbreaks ranges from 17% to 40%. In this work, we carried out a prospective study to investigate the involvement of workers in closed and semiclosed institutions during outbreaks. The attack rates (ARs) and the rate ratios (RRs) were calculated according to the type of transmission and occupational category. The RRs and 95% confidence intervals (CIs) between workers and users were calculated. The mean cycle of quantification (Cq) values were compared according to the genogroup and the presence of symptoms. ARs were higher in person-to-person transmission than in common vehicle outbreaks, and 38.8% of workers were symptomatic. The RR between workers and users was 0.46 (95% CI 0.41–0.52). The ARs in workers were high, particularly in workers with closer contact with users. The mean Cq was lower in patients than in asymptomatic infected persons, although the difference was only significant for genogroup I (GI). The frequency of asymptomatic infected persons suggests that personal hygiene measures should be followed by all workers in the centers affected.

2020 ◽  
Vol 134 (8) ◽  
pp. 717-720 ◽  
Author(s):  
MH Hussain ◽  
M Mair ◽  
P Rea

AbstractObjectiveTo evaluate the prevalence of severe acute respiratory syndrome coronavirus-2 infection in patients presenting with epistaxis to a tertiary otolaryngology unit.MethodsA prospective study was conducted of 40 consecutive patients presenting with epistaxis referred to our tertiary otolaryngology unit. A group of 40 age-matched controls were also included. All patients underwent real-time reverse transcriptase polymerase chain reaction testing for severe acute respiratory syndrome coronavirus-2. Symptoms of fever, cough and anosmia were noted in the study group.ResultsThe mean age was 66.5 ± 22.4 years in the study group. There were 22 males (55 per cent) and 18 females (45 per cent). The mean age in the control group was 66.3 ± 22.4 years (p = 0.935). There were six positive cases for severe acute respiratory syndrome coronavirus-2 (15 per cent) in the epistaxis group and one case (2.5 per cent) in the control group. The difference was statistically significant (p = 0.05).ConclusionEpistaxis may represent a presenting symptom of severe acute respiratory syndrome coronavirus-2 infection. This may serve as a useful additional criterion for screening patients.


2019 ◽  
Author(s):  
Yijun Hu ◽  
Li Li ◽  
Wei Qi ◽  
Zhenhao Liu ◽  
Yingpeng Liu ◽  
...  

AbstractPurposeTo investigate the corneal endothelial cell density (ECD) in eyes with primary pterygium.MethodsWe first conducted a retrospective study to compare the ECD between 1670 eyes with primary pterygium and 4060 eyes without pterygium. Then we designed a prospective study to confirm the critical findings of the retrospective study in 95 patients with unilateral primary pterygium.ResultsIn the retrospective study, the mean preoperative ECD in eyes with primary ptergyium (2453±306 cells/mm2) was statistically significantly lower than those in eyes without pterygium (2529±313 cells/mm2, P<0.0001). However, the difference was minor (76 cells/mm2, 3.1%). In the prospective study, the mean ECD in eyes with unilateral primary pterygium (2480±263 cells/mm2) was not significantly different from those in the contralateral eyes (2527±277 cells/mm2, P=0.20). The hexagonality (P=0.10) or coefficient of variation of size (P=0.15) of corneal endothelial cells was not significantly different between eyes with pterygium and the contralateral eyes.ConclusionPrimary pterygium may not be associated with ECD decrease in our study cohort.


Author(s):  
M. H Badii

Keywords: Estimations, sampling, statisticsAbstract. The notion of statistical estimation both in terms of point and interval is described. The criteria of a good estimator are noted. The procedures to calculate the intervals for the mean, proportions and the difference among two means as well as the confidence intervals for the probable errors in statistics are provided.Palabras clave: Estadística, estimación, muestreoResumen. En la presente investigación se describen la noción de la estimación estadística, tanto de tipo puntual con de forma de intervalo. Se presentan los criterios que debe reunir un estimador bueno. Se notan con ejemplos, la forma de calcular la estimación del intervalo para la media, la proporción y de la diferencia entre dos medias y los intervalos de confianza para los errores probables.


2019 ◽  
Vol 7 (14) ◽  
pp. 2292-2297
Author(s):  
Manahap Verarius F. Pardosi ◽  
Bahagia Loebis ◽  
Muhammad Surya Husada ◽  
Nazli M. Nasution ◽  
Elmeida Effendy ◽  
...  

BACKGROUND: Schizophrenia is a psychopathological syndrome clinic involving cognition, emotion, perception and other aspects from the individual which interferences. This interference is normally started before age 25, and it can affect all social classes. AIM: To find out the difference in total positive and negative syndrome scale (PANSS) scores in schizophrenia between Bataknese and Javanese who have received treatment with risperidone. METHODS: This study is a prospective study. This study used numeric comparative analytic two unpaired groups to observe the differences of PANSS score of the man with schizophrenia between Bataknese and Javanese who had received risperidone treatment. RESULTS: Our study found that the average score of PANSS for Bataknese was 49.76 ± 12.65 and Javanese was 42.43 ± 9.05. CONCLUSION: There was a difference score of PANSS for the man with schizophrenia between Bataknese and Javanese who had received risperidone treatment for 6 weeks (p = 0.037).


2020 ◽  
Vol 10 (3) ◽  
Author(s):  
Vanuza Rosa ◽  
Gabriela Kuzma ◽  
Luana Hornung ◽  
Márcia Bandeira

OBJECTIVE: Benign acute childhood myositis is characterized by acute musculoskeletal involvement leading to transient limitations on deambulation followed by a viral illness. Our study objective to evaluate clinical and laboratory features of patients in a pediatric emergency department. METHODOS: We conducted a prospective study in patients with symptoms and laboratory findings compatible with viral myositis in the period of August 2017 to August 2018. RESULTS: We assessed 20 patients in the period of twelve months. The mean age was 8,25 years. Of these, 83,3% had infectious symptoms in the week before the musculoskeletal involvement. By the time of the diagnosis, the symptoms were: calf pain, reluctance to walk, gait abnormality, diffuse myalgia and calf weakness. The most relevant laboratory finding was the elevation of CPK (mean 3359,556U/L) level, followed by AST (mean 131U/L) and ALT (mean 64,66U/L) elevation. The mean time for symptom relief was 3 days and in 7 days all exams were normal. CONCLUSION: Though the exact incidence of this condition remains undetermined, the lower extremity pain and the gait abnormality is of concern of both parents and health care providers. We emphasize the importance of knowing this condition to avoid unnecessary exams and the delay in the diagnosis of severe conditions.


PEDIATRICS ◽  
1987 ◽  
Vol 79 (4) ◽  
pp. 593-597
Author(s):  
Karen Olness ◽  
John T. MacDonald ◽  
Donald L. Uden

In a prospective study we compared propranolol, placebo, and self-hypnosis in the treatment of juvenile classic migraine. Children aged 6 to 12 years with classic migraine who had no previous specific treatment were randomized into propranolol (at 3 mg/kg/d) or placebo groups for a 3-month period and then crossed over for 3 months. After this 6-month period, each child was taught self-hypnosis and used it for 3 months. Twenty-eight patients completed the entire study. The mean number of headaches per child for 3 months during the placebo period was 13.3 compared with 14.9 during the propranolol period and 5.8 during the self-hypnosis period. Statistical analysis showed a significant association between decrease in headache frequency and self-hypnosis training (P = .045). There was no significant change in subjective or objective measures of headache severity with either therapy.


Author(s):  
Michael S. Borofsky ◽  
Vincent G. Bird

This chapter reviews the results of an important observational study seeking to establish how, in individuals without a history of nephrolithiasis, dietary calcium intake is associated with the risk of symptomatic stone disease. The study found that the mean daily dietary calcium intake was lower in the group who formed stones compared to those who did not and that, after adjusting for covariates, high daily dietary calcium intake was strongly associated with decreased risk of stones.


2019 ◽  
Vol 45 (4) ◽  
pp. 375-382 ◽  
Author(s):  
Lionel Athlani ◽  
Kamel Rouizi ◽  
Jonathan Granero ◽  
Gabriela Hossu ◽  
Alain Blum ◽  
...  

We performed a prospective study to evaluate the values of dynamic four-dimensional computed tomography in assessing suspected chronic scapholunate instability. Forty patients were evaluated with radiographs, arthrography, and four-dimensional computed tomography. On plain radiographs and computed tomography, we found 16 patients with definite scapholunate instability, five with questionable scapholunate instability, and 19 with absence of scapholunate instability. We used four-dimensional computed tomography to evaluate the size of the scapholunate gap during radioulnar deviation. The mean and maximal values of the gap size were lowest in the patients with absence of scapholunate instability and highest in those with definite scapholunate instability. When comparing the scapholunate gap sizes of the patients with absent and questionable scapholunate instability, the range of the gap sizes was significantly higher in the patients with questionable scapholunate instability. We conclude that four-dimensional computed tomography aids assessment of chronic scapholunate instability, which allows the differentiation between patients without and those with definite or questionable scapholunate instability. Level of evidence: II


2013 ◽  
Vol 39 (2) ◽  
pp. 161-166 ◽  
Author(s):  
A. Żyluk ◽  
I. Walaszek ◽  
Z. Szlosser

A prospective study was carried out to investigate any correlation between electrophysiological and sonographic findings in patients with a clinical diagnosis of carpal tunnel syndrome. A total of 113 patients (113 wrists) in 90 women and 23 men, with a mean age of 60 years, underwent sonographic and electrophysiological examination. Fifty-five patients (48%) had mild, 43 (38%) moderate and 12 (11%) had severe conduction disturbances and three patients had normal conduction. Sonographic measurements showed a cross-sectional area of the median nerve of 9.9 mm2 at the forearm and 17.8 mm2 at the tunnel inlet. The mean anteroposterior diameter (height) of the nerve at the tunnel inlet was 2.7 mm, and the lowest height inside the tunnel was 1.8 mm. No correlation was found between sonographic and electrophysiological parameters.


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