Histologic study of periprosthetic osteolytic lesions after AES total ankle replacement. A 22 case series

Background: Peri-implant osteolysis is one of the major complications related to total ankle replacement. The aim of this study was to investigate the short- to midterm incidence of peri-implant osteolysis using computed tomography (CT) as imaging method for the Trabecular Metal Total Ankle (TMTA) implant representing a novel total ankle replacement (TAR) implant design regarding material and surgical technique. Methods: In total, 104 consecutive patients who had a primary TMTA replacement between March 2013 and October 2017 were included in the study. The radiographic evaluation included weightbearing anteroposterior and lateral views at baseline and after 3, 6, and every 12 months postoperatively. A helical CT was undertaken preoperatively and of the 80 patients available to follow up at least 12 months postoperatively, with average time interval between the TAR operation and the latest CT of 39 (range, 12-85) months. Results: Eight of 80 patients had altogether 11 osteolytic lesions around the components on CT images. Seven lesions were found in tibia, 3 in talus, and 1 in distal fibula. Four of the tibial lesions were situated in the medial malleolus and were not in contact with the prosthesis component. The sizes of the osteolytic lesions ranged between 7 and 20 mm, and the average volume of the lesions was 689 mm3. Conclusion: We conclude that the risk of peri-implant osteolysis with the TMTA implant is minimal in short to midterm. The anatomic configuration, unique material, and surgical technique may all contribute to the TMTA implant having a low rate of peri-implant osteolysis. Level of Evidence: Level IV, case series.

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Living With Both a Total Ankle Replacement and an Ankle Fusion: A Qualitative Study From the Patients’ Perspective

Foot & Ankle International ◽

10.1177/10711007211004447 ◽

2021 ◽

pp. 107110072110044

Author(s):

Catherine Conlin ◽

Ryan M. Khan ◽

Ian Wilson ◽

Timothy R. Daniels ◽

Mansur Halai ◽

...

Keyword(s):

Hospital Setting ◽

Case Series ◽

Total Ankle Replacement ◽

Qualitative Description ◽

Level Of Evidence ◽

Foot Placement ◽

Advantages And Disadvantages ◽

Ankle Fusion ◽

Ankle Replacement ◽

Patient Reported

Background: Total ankle replacement (TAR) and ankle fusion are effective treatments for end-stage ankle arthritis. Comparative studies elucidate differences in treatment outcomes; however, the literature lacks evidence demonstrating what outcomes are important to patients. The purpose of this study was to investigate patients’ experiences of living with both a TAR and ankle fusion. Methods: This research study used qualitative description. Individuals were selected from a cohort of patients with TAR and/or ankle fusion (n = 1254). Eligible patients were English speaking with a TAR and contralateral ankle fusion, and a minimum of 1 year since their most recent ankle reconstruction. Surgeries were performed by a single experienced surgeon, and semistructured interviews were conducted by a single researcher in a private hospital setting or by telephone. Ankle Osteoarthritis Scale (AOS) scores, radiographs, and ancillary surgical procedures were collected to characterize patients. Themes were derived through qualitative data analysis. Results: Ten adults (8 men, 2 women), ages 59 to 90 years, were included. Average AOS pain and disability scores were similar for both surgeries for most patients. Participants discussed perceptions of each reconstructed ankle. Ankle fusions were considered stable and strong, but also stiff and compromising balance. TARs were considered flexible and more like a “normal ankle,” though patients expressed concerns about their TAR “turning” on uneven ground. Individuals applied this knowledge to facilitate movement, particularly during a first step and transitioning between positions. They described the need for careful foot placement and attention to the environment to avoid potential challenges. Conclusion: This study provides insight into the experiences of individuals living with a TAR and ankle fusion. In this unusual but limited group of patients, we found that each ankle reconstruction was generally perceived to have different characteristics, advantages, and disadvantages. Most participants articulated a preference for their TAR. These findings can help clinicians better counsel patients on expectations after TAR and ankle fusion, and improve patient-reported outcome measures by better capturing meaningful outcomes for patients. Level of Evidence: Level IV, case series.

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Total Ankle Arthroplasty Survivorship, Complication, and Revision Rates in Patients Younger Than 55 Years

Foot & Ankle Specialist ◽

10.1177/1938640020980925 ◽

2021 ◽

pp. 193864002098092

Author(s):

Devon W. Consul ◽

Anson Chu ◽

Travis M. Langan ◽

Christopher F. Hyer ◽

Gregory Berlet

Keyword(s):

Case Series ◽

Ankle Arthrodesis ◽

Total Ankle Replacement ◽

Implant Survival ◽

Ankle Arthritis ◽

Single Institution ◽

Retrospective Case ◽

Ankle Replacement ◽

End Stage

Total ankle replacement has become a viable alternative to ankle arthrodesis in the surgical management of advanced ankle arthritis. Total ankle replacement has generally been reserved for patients who are older and for those who will have a lower demand on the replacement. The purpose of the current study is to review patient outcomes, complications, and implant survival in patients younger than 55 years who underwent total ankle replacement at a single institution. A single-center chart and radiographic review was performed of consecutive patients who underwent total ankle replacement for treatment of end-stage ankle arthritis. All surgeries were performed by 1 of 5 fellowship-trained foot and ankle surgeons at a single institution. A total of 51 patients met inclusion criteria with a mean follow-up of 31.2 months (SD = 16.2). Implant survival was 94%, There were 7 major complications (13%) requiring an unplanned return to the operating room and 8 minor complications (15%) that resolved with conservative care. The results of this study show that total ankle replacement is a viable treatment option for patients younger than 55 years. Levels of Evidence: A retrospective case series

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Haemophilic arthropathy of the ankle treated by total ankle replacement: a case series

Haemophilia ◽

10.1111/j.1365-2516.2010.02221.x ◽

2010 ◽

Cited By ~ 7

Author(s):

A. BARG ◽

A. ELSNER ◽

D. HEFTI ◽

B. HINTERMANN

Keyword(s):

Case Series ◽

Total Ankle Replacement ◽

Haemophilic Arthropathy ◽

Ankle Replacement

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Supramalleolar Osteotomy for Tibial Component Malposition in Total Ankle Replacement

Foot & Ankle International ◽

10.1177/1071100717709566 ◽

2017 ◽

Vol 38 (9) ◽

pp. 952-956 ◽

Cited By ~ 4

Author(s):

Manja Deforth ◽

Nicola Krähenbühl ◽

Lukas Zwicky ◽

Markus Knupp ◽

Beat Hintermann

Keyword(s):

Tibial Component ◽

Corrective Osteotomy ◽

Distal Tibia ◽

Case Series ◽

Outcome Data ◽

Total Ankle Replacement ◽

Level Of Evidence ◽

Supramalleolar Osteotomy ◽

Ankle Replacement ◽

Surface Angle

Background: Persistent pain despite a total ankle replacement is not uncommon. A main source of pain may be an insufficiently balanced ankle. An alternative to the revision of the existing arthroplasty is the use of a corrective osteotomy of the distal tibia, above the stable implant. This strictly extraarticular procedure preserves the integrity of the replaced joint. The aim of this study was to review a series of patients in whom a corrective supramalleolar osteotomy was performed to realign a varus misaligned tibial component in total ankle replacement. We hypothesized that the supramalleolar osteotomy would correct the malpositioned tibial component, resulting in pain relief and improvement of function. Methods: Twenty-two patients (9 male, 13 female; mean age, 62.6 years; range, 44.7-80) were treated with a supramalleolar osteotomy to correct a painful ankle with a varus malpositioned tibial component. Prospectively recorded radiologic and clinical outcome data as well as complications and reoperations were analyzed. Results: The tibial anterior surface angle significantly changed from 85.2 ± 2.5 degrees preoperatively to 91.4 ± 2.9 degrees postoperatively ( P < .0001), the American Orthopaedic Foot & Ankle Society hindfoot score significantly increased from 46 ± 14 to 66 ± 16 points ( P < .0001) and the patient’s pain score measured with the visual analog scale significantly decreased from 5.8 ± 1.9 to 3.3 ± 2.4 ( P < .001). No statistical difference was found in the tibial lateral surface angle and the range of motion of the ankle when comparing the preoperative to the postoperative measurements. The osteotomy healed in all but 3 patients on first attempt. Fifteen patients (68%) were (very) satisfied, 4 moderately satisfied, and 3 patients were not satisfied with the result. Conclusion: The supramalleolar osteotomy was found to be a reliable treatment option for correcting the varus misaligned tibial component in a painful replaced ankle. However, nonunion (14%) should be mentioned as a possible complication of this surgery. Nonetheless, as a strictly extraarticular procedure, it did not compromise function of the previously replaced ankle, and it was shown to relieve pain without having to have revised a well-fixed ankle arthroplasty. Level of evidence: Level IV, case series.

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Simultaneous Bilateral Total Ankle Replacement Using the S.T.A.R.: A Case Series

Foot & Ankle International ◽

10.3113/fai.2010.0086 ◽

2010 ◽

Vol 31 (1) ◽

pp. 86-89 ◽

Cited By ~ 9

Author(s):

Alexia Karantana ◽

John Martin Geoghegan ◽

Mayank Shandil ◽

Sunil Dhar

Keyword(s):

Case Series ◽

Total Ankle Replacement ◽

Ankle Replacement

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Total Ankle Replacement Conversion to Tibiotalocalcaneal Arthrodesis With Bulk Femoral Head Allograft and Pseudoelastic Intramedullary Nail Providing Sustained Joint Compression

Foot & Ankle Orthopaedics ◽

10.1177/2473011418804487 ◽

2018 ◽

Vol 3 (4) ◽

pp. 247301141880448

Author(s):

Mark Jay Conklin ◽

Kathryn Elizabeth Smith ◽

Jeremy Webster Blair ◽

Kenneth Michael Dupont

Keyword(s):

Femoral Head ◽

Intramedullary Nail ◽

Case Series ◽

Preliminary Evidence ◽

Total Ankle Replacement ◽

Level Of Evidence ◽

Computed Tomographic ◽

Tibiotalocalcaneal Arthrodesis ◽

First Case ◽

Ankle Replacement

Tibiotalocalcaneal (TTC) arthrodesis is commonly performed to salvage a failed total ankle replacement. These salvage procedures are complicated by significant bone loss from the ankle replacement and are associated with low patient satisfaction. Here, we describe 2 cases of patients who presented with a failed total ankle replacement and underwent arthrodesis using a bulk femoral head allograft and a novel pseudoelastic intramedullary nail. The intramedullary nail contains an internal pseudoelastic element that adapts to bone resorption and settling allowing for compression to be maintained at the arthrodesis sites throughout healing. In the first case, a 65-year-old woman with a failed total ankle replacement underwent TTC arthrodesis. The second case involved an obese 53-year-old woman who had previously undergone 2 total ankle replacement procedures that resulted in unsuccessful outcomes. In both cases, union was demonstrated on computed tomographic scan by 6 months. At 2 years postsurgery, both patients were satisfied with the procedure. These cases provide preliminary evidence that tibiotalocalcaneal arthrodesis with a pseudoelastic IM nail and structural allograft is an appropriate treatment for failed total ankle replacements. Level of Evidence: Level IV, therapeutic, case series.

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Periprosthetic Fracture of the Talus following Total Ankle Replacement: A Case Series

Foot & Ankle Orthopaedics ◽

10.1177/2473011420s00186 ◽

2020 ◽

Vol 5 (4) ◽

pp. 2473011420S0018

Author(s):

Jonathan Day ◽

Jaeyoung Kim ◽

Scott J. Ellis ◽

Jonathan T. Deland ◽

Martin J. O’Malley ◽

...

Keyword(s):

Clinical Outcomes ◽

Periprosthetic Fracture ◽

Case Series ◽

Total Ankle Replacement ◽

Periprosthetic Fractures ◽

Ankle Arthritis ◽

Radiographic Findings ◽

Unexplained Pain ◽

Ankle Replacement ◽

Talar Fractures

Category: Ankle; Ankle Arthritis; Trauma Introduction/Purpose: Although total ankle replacement (TAR) for the treatment of end-stage ankle arthritis has been shown to have excellent radiographic and clinical outcomes, there is a risk for complications such as periprosthetic fractures. While periprosthetic fractures of the tibia are well described in the literature, little is known about such fractures involving the talus. The purpose of this case series is to describe the radiographic findings and surgical management of talar fractures sustained after placement of total ankle prostheses. Methods: We retrospectively reviewed 489 patients who underwent total ankle replacement from June 2015 to March 2019, and identified five cases (2 males, 3 females, average age 45.7 years) in which patients sustained a periprosthetic fracture of the talus. All patients presented symptomatically with ankle pain during postoperative follow-up, and fractures of the talus were confirmed on computed tomography (CT) imaging. One patient had psoriatic arthritis and four patients had primary osteoarthritis of the ankle. CTs were reviewed to confirm location and pattern of the fracture, as well as related pathology such as osteolysis and subsidence. Hospital charts and operative reports were reviewed to record patient demographics and postoperative management including reoperations. Results: Overall the incidence of talar fractures was 1% (5/489) and all occurred in implants with a talar stem (4 INBONE II, 1 Salto Talaris). All fractures extended from the stem of the talar component into the subtalar joint, with one case of a non- displaced fracture. Osteolysis surrounding the talar stem was observed in all cases, with subsidence of the talar component observed in four out of five patients on CT. All five patients presented symptomatically and underwent reoperation (1 revision of talar component with ORIF, 3 subtalar fusions, 1 tibiotalar fusion). Conclusion: The findings in this case series suggest that periprosthetic fractures of the talus following total ankle replacement is a possible complication of stemmed implants and is associated with poor clinical outcomes requiring reoperation. Therefore, a periprosthetic fracture of the talus should be considered in a patient with unexplained pain and evidence of radiographic osteolysis around the stemmed component. [Table: see text]

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Total Ankle Replacement in Hemophilia

Cardiovascular & Haematological Disorders - Drug Targets ◽

10.2174/1871529x19666191210110626 ◽

2020 ◽

Vol 20 (2) ◽

pp. 88-92

Author(s):

Emerito C. Rodriguez-Merchan

Keyword(s):

Adverse Events ◽

Daily Living ◽

Case Reports ◽

Case Series ◽

Total Ankle Replacement ◽

Cochrane Library ◽

Hemophilic Arthropathy ◽

Accessible Information ◽

Ankle Replacement

Introduction: Severe ankle hemophilic arthropathy can be a calamitous sign of severe hemophilia with important inferences for activities of daily living. Aims: To summarize the contemporary, accessible information on Total Ankle Replacement (TAR) for ankle hemophilic arthropathy. Methods: A search of Cochrane Library and PubMed (MEDLINE) regarding the role of TAR in ankle hemophilic arthropathy. Results: The insufficient information regarding the results of TAR for hemophilic arthropathy is confined to scanty case series and case reports. An evaluation of the accessible literature reveals encouraging but inconstant outcomes. The reported rate of adverse events is 33%. The reported anticipated survival of TAR is 94% at 5 years, 85% at 10 years and 70% at 15 years. Conclusion: Whereas people with advanced hemophilic arthropathy of the ankle are prone to ameliorate pain and range of motion following TAR, there is deficient knowledge to regularly recommend its use. Adverse events and infection percentages are disturbing. Moreover, the lack of survival analysis knowledge makes it difficult to assess the benefit to people with hemophilia. TAR is a demanding surgical procedure and its survival is not comparable to that after hip or knee replacement.

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