Perioperative and long term quality of life in pancreatoduodenectomy - Analysis from a German prospective multicenter trial (RECOPANC) -

Pancreatology ◽  
2018 ◽  
Vol 18 (4) ◽  
pp. S165
Author(s):  
Ulrich Friedrich Wellner ◽  
Sergey Zemskov ◽  
Aleksey Dronov ◽  
Hryhoriy Lapshyn ◽  
Ekaterina Petrova ◽  
...  
2014 ◽  
Vol 32 (15_suppl) ◽  
pp. 4563-4563
Author(s):  
Peter Albers ◽  
Florian Fischer ◽  
Henning Flechtner ◽  
Michael Hartmann ◽  
Roswitha Siener

2021 ◽  
pp. 1-7
Author(s):  
Jan-Niclas Mumm ◽  
Benedikt Klehr ◽  
Severin Rodler ◽  
Alexander Kretschmer ◽  
Theresa Vilsmaier ◽  
...  

<b><i>Objective:</i></b> The aim of this study was to assess the security, value, and efficacy of the second-generation AdVance male sling XP (Boston Scientific®), after implementation in 2010 with advantageous modifications in the sling structure and needle shape, in a prospective multicenter long-term follow-up study. <b><i>Methods:</i></b> In total, 115 patients were included. Exclusion criteria were earlier incontinence (UI) surgery, nocturnal UI, former radiotherapy, or night-time incontinence. We also excluded patients with a functional urethra &#x3c;1 cm in a preoperatively performed repositioning test. A consistent 24-h pad test, International Quality of Life (IQOL) score, visual analog pain scale (VAS), International Consultation-Incontinence Questionnaire (ICIQ-UI SF), International Index of Erectile Function (IIEF-5), International Prostate Symptom Score (IPSS), and Patient Global Impression of Improvement (PGI-I) scores were requested postoperatively. <b><i>Results:</i></b> The 24-month follow-up (114 patients) revealed 64.0% cured and 28.8% improved patients. Mean urine loss was reduced significantly to 19.0 g (<i>p</i> &#x3c; 0.001). A mean PGI score of 1.5 and a mean VAS score of 0.2 were obtained. The 60-month follow-up (59 patients) revealed 57.6% cured and 25.4% improved patients. Mean urine loss was reduced significantly to 18.3 g (<i>p</i> &#x3c; 0.001). A mean PGI score of 1.6 and a mean VAS score of 0.2 were obtained. <b><i>Conclusions:</i></b> The AdVance XP displays excellent continence results and secure effectiveness over a 5-year period. Moreover, these data are demonstrating low complication rates and improved quality of life in the long-term use of AdVance XP.


2004 ◽  
Vol 171 (4S) ◽  
pp. 245-246
Author(s):  
Roswitha Siener ◽  
Henning Flechtner ◽  
Peter Albers ◽  
Sabine Kliesch ◽  
Lothar Weissbach ◽  
...  

2007 ◽  
Vol 246 (3) ◽  
pp. 481-490 ◽  
Author(s):  
Victor W. Fazio ◽  
Massarat Zutshi ◽  
Feza H. Remzi ◽  
Yann Parc ◽  
Reinhard Ruppert ◽  
...  

Author(s):  
Manuela Nickler ◽  
Daniela Schaffner ◽  
Mirjam Christ-Crain ◽  
Manuel Ottiger ◽  
Robert Thomann ◽  
...  

AbstractBackground:Most clinical research investigated prognostic biomarkers for their ability to predict cardiovascular events or mortality. It is unknown whether biomarkers allow prediction of quality of life (QoL) after survival of the acute event. Herein, we investigated the prognostic potential of well-established inflammatory/cardiovascular blood biomarkers including white blood cells (WBC), C-reactive protein (CRP), procalcitonin (PCT), pro-adrenomedullin (proADM) and pro-atrial natriuretic peptide (proANP) in regard to a decline in QoL in a well-defined cohort of patients with community-acquired pneumonia (CAP).Methods:Within this secondary analysis including 753 patients with a final inpatient diagnosis of CAP from a multicenter trial, we investigated associations between admission biomarker levels and decline in QoL assessed by the EQ-5D health questionnaire from admission to day 30 and after 6 years.Results:Admission proADM and proANP levels significantly predicted decline of the weighted EQ-5D index after 30 days (n=753) with adjusted odds ratios (ORs) of 2.0 ([95% CI 1.1–3.8]; p=0.027) and 3.7 ([95% CI 2.2–6.0]; p<0.001). Results for 6-year outcomes (n=349) were similar with ORs of 3.3 ([95% CI 1.3–8.3]; p=0.012) and 6.2 ([95% CI 2.7–14.2]; p<0.001). The markers were associated with most of the different QoL dimensions including mobility, self-care, and usual activities, but not pain/discomfort and to a lesser degree anxiety/depression and the visual analogue scale (VAS). Initial WBC, PCT and CRP values did not well predict QoL at any time point.Conclusions:ProADM and proANP accurately predict short- and long-term decline in QoL across most dimensions in CAP patients. It will be interesting to reveal underlying physiopathology in future studies.


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