Medical follow up assessments of iPrognosis application users for early Parkinson's disease detection

2020 ◽  
Vol 79 ◽  
pp. e37
Author(s):  
L. Klingelhoefer ◽  
S. Bostanjopoulou ◽  
D. Trivedi ◽  
S. Hadjidimitriou ◽  
D. Hausbrand ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Disease Detection ◽  
Early Parkinson’S Disease

Gender differences in non-motor symptoms in early Parkinson's disease: A 2-years follow-up study on previously untreated patients

2014 ◽  
Vol 20 (8) ◽  
pp. 850-854 ◽  
Author(s):  
Marina Picillo ◽  
Roberto Erro ◽  
Marianna Amboni ◽  
Katia Longo ◽  
Carmine Vitale ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Gender Differences ◽  
Parkinson's Disease ◽  
Motor Symptoms ◽  
Follow Up Study ◽  
Non Motor Symptoms ◽  
Early Parkinson’S Disease

scholarly journals The Clinical Non-Motor Connectome in Early Parkinson’s Disease

2020 ◽  
Vol 10 (4) ◽  
pp. 1797-1806
Author(s):  
Nico J. Diederich ◽  
Nicolas Sauvageot ◽  
Vannina Pieri ◽  
Géraldine Hipp ◽  
Michel Vaillant
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Early Stage ◽  
Correlation Coefficients ◽  
P Value ◽  
The Mean ◽  
Disease Initiation ◽  
Non Motor Symptoms ◽  
Early Parkinson’S Disease

Background: Non-motor symptoms (NMS) of various anatomical origins are seen in early stage idiopathic Parkinson’s disease (IPD). Objective: To analyse when and how NMS are linked together at this stage of the disease. Methods: Prospective study recruiting 64 IPD patients with ≤3 years of disease duration and 71 age-matched healthy controls (HC). NMS were clustered in 7 non-motor domains (NMD): general cognition, executive function, visuospatial function, autonomic function, olfaction, mood, and sleep. Correlation coefficients ≥|0.3| were considered as significant. Bootstrapped correlation coefficients between the scores were generated in both groups. Fourteen IPD patients and 19 HC were available for a follow-up study two years later. Results: The mean age of both groups was similar. 58% of IPD patients and 37% of HC were male (p = 0.01). At baseline IPD patients performed less well than HC on all NMD (p value between 0.0001 and 0.02). Out of 91 possible correlations between NMD, 21 were significant in IPD patients and 14 in HC at the level of ≥|0.3|. The mean correlation level was higher in IPD patients than in HC, as evidenced by the higher box plot of correlation coefficients. Visuospatial scores at baseline were predictive of the motor deterioration at the follow-up exam. Conclusion: At early IPD stage various NMS are linked together, although not connected by anatomical networks. Such a clinical NMD connectome suggests almost synchronous disease initiation at different sites as also supported by fMRI findings. Alternatively, there may be compensation-driven interconnectivity of NMD.

Transcranial magnetic stimulation follow-up study in early Parkinson's disease: A decline in compensation with disease progression?

2015 ◽  
Vol 30 (8) ◽  
pp. 1098-1106 ◽  
Author(s):  
Maja Kojovic ◽  
Panagiotis Kassavetis ◽  
Matteo Bologna ◽  
Isabel Pareés ◽  
Ignacio Rubio-Agusti ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Transcranial Magnetic Stimulation ◽  
Disease Progression ◽  
Magnetic Stimulation ◽  
Follow Up Study ◽  
Early Parkinson’S Disease

Lower serum uric acid is associated with mild cognitive impairment in early Parkinson’s disease: a 4-year follow-up study

2016 ◽  
Vol 123 (12) ◽  
pp. 1399-1402 ◽  
Author(s):  
Maria Teresa Pellecchia ◽  
Riccardo Savastano ◽  
Marcello Moccia ◽  
Marina Picillo ◽  
Pietro Siano ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Uric Acid ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Serum Uric Acid ◽  
Lower Serum ◽  
Follow Up Study ◽  
Early Parkinson’S Disease

Language-Independent Bimodal System for Early Parkinson’s Disease Detection

2021 ◽  
pp. 397-413
Author(s):  
Catherine Taleb ◽  
Laurence Likforman-Sulem ◽  
Chafic Mokbel
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Disease Detection ◽  
Early Parkinson’S Disease

Striatal subregional 6-[18F]fluoro-L-dopa uptake in early Parkinson's disease: A two-year follow-up study

2006 ◽  
Vol 21 (7) ◽  
pp. 958-963 ◽  
Author(s):  
Anna Brück ◽  
Sargo Aalto ◽  
Elina Nurmi ◽  
Tero Vahlberg ◽  
Jörgen Bergman ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Follow Up Study ◽  
Early Parkinson’S Disease ◽  
Dopa Uptake

scholarly journals Combining clinical and biofluid markers for early Parkinson's disease detection

2017 ◽  
Vol 5 (1) ◽  
pp. 109-114 ◽  
Author(s):  
Zhenwei Yu ◽  
Tessandra Stewart ◽  
Jan Aasly ◽  
Min Shi ◽  
Jing Zhang
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Disease Detection ◽  
Early Parkinson’S Disease
Sign in / Sign up

Export Citation Format

Share Document