scholarly journals Impact of chronic kidney disease definition on assessment of its incidence and risk factors in patients with newly diagnosed type 1 and type 2 diabetes in the UK: A cohort study using primary care data from the United Kingdom

2020 ◽  
Vol 14 (4) ◽  
pp. 381-387
Author(s):  
Antonio González-Pérez ◽  
Maria E. Saéz ◽  
David Vizcaya ◽  
Marcus Lind ◽  
Luis A. García Rodríguez
2019 ◽  
Vol 21 (7) ◽  
pp. 1576-1584 ◽  
Author(s):  
John M. Dennis ◽  
William E. Henley ◽  
Andrew P. McGovern ◽  
Andrew J. Farmer ◽  
Naveed Sattar ◽  
...  

2022 ◽  
Vol 16 (1) ◽  
pp. 18-25
Author(s):  
Linda Nazarko

The coronavirus (COVID-19) pandemic has highlighted the importance of public health in the UK and globally. The UK's death rates and obesity rates are related and many people in the UK experience poor health because they are overweight or obese ( Lobstein, 2021 ; Mohammad et al, 2021 ). Obesity increases the risks of developing type 2 diabetes. People with both type 1 and type 2 diabetes are at greater risk of developing severe COVID symptoms, of requiring hospital treatment and of poor outcomes and death ( Barron et al, 2020 ). This article, the fifth in a series, examines risk factors for type 2 diabetes and explains how readers can reduce their risk of developing type 2 diabetes.


2013 ◽  
Vol 31 (3) ◽  
pp. 357-365 ◽  
Author(s):  
A. McGrogan ◽  
J. Snowball ◽  
C. S. de Vries
Keyword(s):  

2017 ◽  
Vol 10 (12) ◽  
pp. 713-720
Author(s):  
Fatima A Telford

There are 31 500 children in the UK with diabetes, the second-most-common chronic disease in childhood, after asthma. Most have type 1 diabetes, those remaining have type 2 diabetes, maturity onset diabetes of the young, or cystic-fibrosis-related diabetes. About 25% of newly diagnosed children present with diabetic ketoacidosis. The NHS spends about £1 000 000 per hour on diabetes and GPs have a central role in early diagnosis, prevention of complications, prompt referral and coordination of care. Engagement with good advice and support is essential for young people with diabetes and their families. This article gives an overview of the management of childhood diabetes.


Angiology ◽  
2021 ◽  
pp. 000331972098459
Author(s):  
Yao-dong Ding ◽  
Yu-qiang Pei ◽  
Rui-Wang ◽  
Jia-xin Yang ◽  
Ying-xin Zhao ◽  
...  

We investigated the association between plasma microRNA (miR)-204 and coronary artery calcification (CAC) in patients with type 2 diabetes mellitus (T2DM). We consecutively enrolled 179 individuals with T2DM who underwent coronary computed tomography at Anzhen Hospital from January 2015 to September 2016. The CAC score (CACS) was expressed in Agatston units and >10 Hounsfield units were defined as CAC-positive status. Significant CAC was observed in 98 (54.7%) patients. Plasma miR-204 levels (relative expression) were significantly lower in patients with significant CAC than controls (1.001 ± 0.100 vs 0.634 ± 0.211, P < .001). Plasma miR-204 levels were also negatively correlated with the glycosylated hemoglobin A1c (HbA1c) level (r = −0.702, P < .001), CACS (r = −0.710, P < .001), and the United Kingdom Prospective Diabetes Study (UKPDS) score (r = −0.355, P < .001). After multivariate logistic analyses, plasma miR-204 levels were still significantly and independently associated with the presence of CAC (odds ratio = 0.103, CI = 0.018-0.583, P < .001) after adjustment for conventional risk factors. Receiver operating characteristic curve analysis showed that plasma miR-204 levels can predict the severity and extent of CAC, and the specificity was higher than that of the traditional risk factors UKPDS score and HbA1c. In conclusion, the downregulation of miR-204 was independently associated with CAC in patients with T2DM.


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