Antimicrobial photodynamic therapy (aPDT) with curcumin and LED, as an enhancement to scaling and root planing in the treatment of residual pockets in diabetic patients: A randomized and controlled split-mouth clinical trial

2019 ◽  
Vol 27 ◽  
pp. 388-395 ◽  
Author(s):  
Camila Ayumi Ivanaga ◽  
Daniela Maria Janjacomo Miessi ◽  
Marta Aparecida Alberton Nuernberg ◽  
Marina Módolo Claudio ◽  
Valdir Gouveia Garcia ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Photodynamic Therapy ◽  
Diabetic Patients ◽  
Antimicrobial Photodynamic Therapy ◽  
Scaling And Root Planing ◽  
Root Planing

scholarly journals EFFICACY OF PHOTODYNAMIC THERAPY AS AN ADJUNCT TO NON – SURGICAL PERIODONTAL THERAPY IN TYPE-2 DIABETES MELLITUS PATIENT

2022 ◽  
Vol 6 (1) ◽  
Author(s):  
Roshni Ghosh ◽  
Pradeep Shukla ◽  
Gaurav Malhotra ◽  
Prerna Kataria ◽  
Preeti Shukla ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Control Group ◽  
Diabetic Patients ◽  
Antimicrobial Photodynamic Therapy ◽  
Scaling And Root Planing ◽  
Root Planing ◽  
Probing Depth ◽  
The Mean ◽  
Attachment Level

Background: To Evaluate the additional benefit of Antimicrobial Photodynamic therapy, if any in the glycemic control of type 2 diabetes mellitus  chronic periodontitis patients . Methods:  Fifty  diabetic patients with chronic periodontitis were taken for the study who met the inclusion criteria of clinical attachment loss ?3 to 5 mm at ? 30% of sites and bleeding on probing present in two different quadrants . After SRP ( Scaling and root planing ) , one quadrant was selected for aPDT while other served as a control group. Clinical parameters i.e. Plaque index, Probing depth ,Relative attachment level and HBA1c were measured at baseline, 1 week , 1month and 3 months. Results: Statistically significant differences in the mean probing depth, Relative attachment level, plaque deposit, and HBA1c were found between baseline and 12 weeks post-treatment for both groups. No significant differences in glucose levels were detected among the two  groups in 1 week . Reduction in the mean HbA1c level after treatment was observed in both groups in 1 month and 3 months . Conclusion:  Antimicrobial Photodynamic Therapy when used in addition to scaling and root planing yields significant improvement of  mean probing depth , Plaque deposit ,Relative attachment levels,  periodontal status and reduction of HbA1c levels in treatment of diabetic patients with periodontitis when comparing the test group to the control group. Keywords: photodynamic therapy , scaling and root planing, glycated haemoglobin ,Randomized controlled trial

Evaluation of Subantimicrobial Dose Doxycycline as an Adjunct to Scaling and Root Planing in Chronic Periodontitis Patients with Diabetes: A Randomized, Placebo-Controlled Clinical Trial

2010 ◽  
Vol 11 (3) ◽  
pp. 9-16 ◽  
Author(s):  
Satish Gupta ◽  
Manohar L. Bhongade ◽  
Vikas Deo ◽  
Ritika Jaiswal
Keyword(s):  
Clinical Trial ◽  
Chronic Periodontitis ◽  
Test Group ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
Diabetic Patients ◽  
Scaling And Root Planing ◽  
Pocket Depth ◽  
Root Planing ◽  
Patients With Diabetes

Abstract Aim Diabetic patients have more severe periodontal destruction, but periodontal therapy can improve metabolic control. Recently, interest has focused on the use of subantimicrobial dose doxycycline (SDD) as a treatment paradigm. Therefore, this study was undertaken to evaluate clinical efficacy of SDD with scaling and root planning (SRP) in chronic periodontitis patients with diabetes. Methods and Materials Twenty chronic periodontitis patients with diabetes mellitus were randomly allocated to either a test and a control group. Clinical measurements were recorded at baseline and at six months for probing pocket depth (PPD), clinical attachment level (CAL), and gingival recession (GR). After SRP, patients in the test group were instructed to take SDD 20-mg capsules twice a day while patients in the control group took a placebo twice a day. Both groups were on this regimen for a six-month period. Results A greater reduction in mean PPD was demonstrated in patients in the test group compared to the control group. The mean CAL increase observed in the test group was significantly greater (0.67 mm) than that in the control group. Conclusion It can be concluded that SRP, in conjunction with the SDD therapy described, is more effective then SRP alone in terms of CAL gain and PPD reduction in diabetic patients with severe periodontal disease. Clinical Significance Given the widespread prevalence of both chronic periodontitis and diabetes, the proposed treatment approach will prove to be of great value and contribute significantly to the overall health of the patients. Citation Deo V, Gupta S, Bhongade ML, Jaiswal R. Evaluation of Subantimicrobial Dose Doxycycline as an Adjunct to Scaling and Root Planing in Chronic Periodontitis Patients with Diabetes: A Randomized, Placebo-Controlled Clinical Trial. J Contemp Dent Pract [Internet]. 2010 May; 11(3):009-016. Available from: http://www.thejcdp.com/journal/view/volume11- issue3-deo.

scholarly journals Assessment of the Effect of Photodynamic Therapy on Treatment of Moderate-to-Severe Periodontitis; a Randomized Clinical Trial Study

2016 ◽  
Vol 9 (4) ◽  
pp. 83
Author(s):  
Babak Amoian ◽  
Aida Mirzaee ◽  
Seyed Mostafa Hosseini
Keyword(s):  
Clinical Trial ◽  
Photodynamic Therapy ◽  
Randomized Clinical Trial ◽  
Chronic Periodontitis ◽  
Time Interval ◽  
Clinical Parameters ◽  
Scaling And Root Planing ◽  
Bleeding On Probing ◽  
Treatment Groups ◽  
Root Planing

<p><strong>BACKGROUND &amp; AIM: </strong>Photodynamic therapy is a localized non-invasive treatment modality for the periodontal disease. Some evidences have shown that this technique is effective in improving the treatment outcome. This study compared the effects of photodynamic therapy with and without scaling and root planing and scaling and root planing alone on the clinical parameters of the chronic periodontitis.</p><p><strong>MATERIALS &amp; METHODS: </strong>In this single-blind, randomized clinical trial, 30 chronic periodontitis patients (10 for each modality) were selected and three different methods; photodynamic therapy alone (Group1) by FotoSan 630 system, scaling and root planning (SRP) alone (Group2), scaling and root planing combined with photodynamic therapy (Group3) were done for them randomly. Clinical parameters of probing pocket depth (PPD), bleeding on probing (BOP), and clinical attachment level (CAL) were measured at the baseline and 3, 6 and 12 weeks later. One-sided analysis of variance test was used to analyze PPD and CAL among the treatment groups in each time interval while the paired comparisons were carried out by employment of Dunnett’s test. The treatment groups were statically analyzed by the chi-square test regarding BOP. <strong></strong></p><p><strong>RESULTS: </strong>Before the treatment; no significant differences observed among treatment modalities regarding clinical parameters; while the differences were significant at three weeks (p&lt;0.0001 for PPD and CAL; p&lt;0.001 for BOP); six weeks (p&lt;0.0001 for PPD and CAL, p&lt;0.002 for BOP); and 12 weeks after the treatment (all: p&lt;0.0001). The least PPD and CAL values and the most frequency of non-bleeding on probing status were measured for PDT+SRP modality at three, six, and twelve weeks after the treatment.</p><p><strong>CONCLUSION: </strong>Photodynamic therapy supported the clinical parameters of periodontitis similar to SRP; however, PDT combined with SRP demonstrated a better result than that of SRP alone. Therefore, PDT combined with SRP can be used to improve outcomes of clinical parameters of periodontitis as compared to SRP alone in the short-term.</p>

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