Sodium caprylate induced precipitation post Protein A chromatography as an effective means for host cell protein clearance

2019 ◽  
Vol 164 ◽  
pp. 105460
Author(s):  
Yan Wan ◽  
Ting Zhang ◽  
Tao Chen ◽  
Ying Wang ◽  
Yifeng Li
Keyword(s):  
Host Cell ◽  
Effective Means ◽  
Protein A ◽  
Cell Protein ◽  
Host Cell Protein ◽  
Protein Clearance ◽  
Sodium Caprylate

Demonstration of Robust Host Cell Protein Clearance in Biopharmaceutical Downstream Processes

2008 ◽  
Vol 24 (3) ◽  
pp. 615-622 ◽  
Author(s):  
A.A. Shukla ◽  
C. Jiang ◽  
J. Ma ◽  
M. Rubacha ◽  
L. Flansburg ◽  
...  
Keyword(s):  
Host Cell ◽  
Cell Protein ◽  
Host Cell Protein ◽  
Protein Clearance ◽  
Downstream Processes

Host cell protein adsorption characteristics during protein a chromatography

2012 ◽  
Vol 28 (4) ◽  
pp. 1037-1044 ◽  
Author(s):  
Richard D. R. Tarrant ◽  
M. Lourdes Velez-Suberbie ◽  
Andrew S. Tait ◽  
C. Mark Smales ◽  
Daniel G. Bracewell
Keyword(s):  
Host Cell ◽  
Protein Adsorption ◽  
Protein A ◽  
Cell Protein ◽  
Host Cell Protein ◽  
Adsorption Characteristics

The dynamics of the CHO host cell protein profile during clarification and protein A capture in a platform antibody purification process

2012 ◽  
Vol 110 (1) ◽  
pp. 240-251 ◽  
Author(s):  
Catherine E.M. Hogwood ◽  
Andrew S. Tait ◽  
Nadejda Koloteva-Levine ◽  
Daniel G. Bracewell ◽  
C. Mark Smales
Keyword(s):  
Host Cell ◽  
Protein Profile ◽  
Protein A ◽  
Cell Protein ◽  
Purification Process ◽  
Host Cell Protein ◽  
Antibody Purification

scholarly journals A modular and adaptive mass spectrometry-based platform for support of bioprocess development toward optimal host cell protein clearance

mAbs ◽  
2017 ◽  
Vol 9 (4) ◽  
pp. 654-663 ◽  
Author(s):  
Donald E. Walker ◽  
Feng Yang ◽  
Joseph Carver ◽  
Koman Joe ◽  
David A. Michels ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Host Cell ◽  
Cell Protein ◽  
Bioprocess Development ◽  
Host Cell Protein ◽  
Protein Clearance
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