Therapeutic prospects to treat skeletal muscle wasting in COPD (chronic obstructive lung disease)

2006 ◽  
Vol 109 (1-2) ◽  
pp. 162-172 ◽  
Author(s):  
Michelle J. Hansen ◽  
Rosa C. Gualano ◽  
Steve Bozinovski ◽  
Ross Vlahos ◽  
Gary P. Anderson
Keyword(s):  
Skeletal Muscle ◽  
Lung Disease ◽  
Obstructive Lung Disease ◽  
Muscle Wasting ◽  
Chronic Obstructive Lung Disease ◽  
Chronic Obstructive ◽  
Skeletal Muscle Wasting

Myoglobin Content in Leg Skeletal Muscle in Patients with Chronic Obstructive Lung Disease

Respiration ◽  
1984 ◽  
Vol 45 (1) ◽  
pp. 35-38 ◽  
Author(s):  
Peter Möller ◽  
Kjell Hellström ◽  
Inga Lill Hermansson
Keyword(s):  
Skeletal Muscle ◽  
Lung Disease ◽  
Obstructive Lung Disease ◽  
Chronic Obstructive Lung Disease ◽  
Chronic Obstructive

Intracellular acid-base and electrolyte metabolism in skeletal muscle of patients with chronic obstructive lung disease and acute respiratory failure

1986 ◽  
Vol 71 (6) ◽  
pp. 703-712 ◽  
Author(s):  
E. Fiaccadori ◽  
S. Del Canale ◽  
U. Arduini ◽  
C. Antonucci ◽  
E. Coffrini ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Respiratory Failure ◽  
Acute Respiratory Failure ◽  
Lung Disease ◽  
Obstructive Lung Disease ◽  
Chronic Obstructive Lung Disease ◽  
Magnesium Content ◽  
Chronic Obstructive ◽  
Intracellular Acidosis ◽  
Total Acid

1. Quadriceps femoris muscle needle biopsies were performed in 21 patients with chronic obstructive lung disease (COLD) and acute respiratory failure (ARF) and in 21 age-matched healthy control subjects. 2. Muscle samples were analysed to obtain intracellular bicarbonate and pH values from total acid-labile carbon dioxide content. Muscle potassium, magnesium and sodium content were also determined, as well as water compartments. 3. Skeletal muscle of COLD patients with ARF showed intracellular acidosis and reduced potassium and magnesium content. Total muscle water increase was linked to extracellular water increment. 4. It was concluded that in COLD patients with ARF an overall derangement of skeletal muscle metabolism is present.

Hemodynamic Characteristics in Chronic Obstructive Lung Disease as Related to Cardiac Size

Respiration ◽  
1981 ◽  
Vol 41 (1) ◽  
pp. 25-32 ◽  
Author(s):  
J. Hutsebaut ◽  
G. Scano ◽  
P. Garcia-Herreros ◽  
S. Degré ◽  
A. De Coster ◽  
...  
Keyword(s):  
Lung Disease ◽  
Obstructive Lung Disease ◽  
Chronic Obstructive Lung Disease ◽  
Chronic Obstructive ◽  
Hemodynamic Characteristics
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