Abstract
A gradient of a blood flow velocity on the surface of a blood vessel is one of the clinical medicine concerns from the view point of prevention of the arteriosclerosis.
In previous study, we formulated a relationship between the pressure and a flow velocity based on the coupled wave theory of elastic pipes and Newtonian fluids [1]. In addition, a flow velocity distribution and a wall shear stress are estimated by using the blood pressure data, which are non-invasively obtained by the tonometry method. This method is quasi-analytical method to apply the coupled wave theory for industrial flow field inside steel pipes proposed by Urata [4] to blood vessel, and has the advantage of systematic estimator compared with the numerical calculation. However, the coupled wave theory has applied to the elastic pipes that were assumed to be infinitely long. In addition, a single wave was assumed to be dominant within the elastic pipes and the Newtonian fluids. Therefore, in order to apply various length vessels in clinical field, the boundary of the blood vessels that varies from site to site, and the natural vibration characteristics that depend on the boundary conditions, could not be reflected in the wall shear stress estimation. In general, in order to solve the forced vibration with the boundary condition, it is necessary to clarify natural frequency and natural mode as natural vibration characteristics of structure.
In this study, we introduce the spring supported elastic pipes to the coupled wave theory and formulated a relationship between the natural vibration characteristics and the boundary conditions. In this proposed method, the spring-supported elastic pipe has a feature that can be treated as an arbitrary boundary condition of an artery by giving an appropriate spring coefficients. Therefore, it is easy to apply to various types of blood vessels clinically. By investigating the natural vibration characteristics of blood vessels that varies from site to site, it may be possible to clarify fluctuations of blood flow in response to blood pressure with some frequency-bands. In addition, natural angular frequencies and natural modes of the spring supported elastic pipes and the Newtonian fluids were estimated for general blood vessel based on the coupled wave theory. In the result, the natural angular frequencies and the natural modes that reflect the clinical vibration characteristics to some extent can be estimated. On the other hand, particular modes may not reflect boundary condition, and further examination of the relationship between natural vibration characteristics and boundary condition is needed.
Quantum coupled-wave theory of price formation in financial markets: Price measurement, dynamics and ergodicity
