Associations between temperament and gene polymorphisms in the brain dopaminergic system and the adrenal gland of sheep

2016 ◽  
Vol 153 ◽  
pp. 19-27 ◽  
Author(s):  
Xiaoyan Qiu ◽  
Jason Ledger ◽  
Chen Zheng ◽  
Graeme B. Martin ◽  
Dominique Blache
Keyword(s):  
Adrenal Gland ◽  
Gene Polymorphisms ◽  
Dopaminergic System ◽  
The Brain

P.1.c.020 Regulation of cytochrome P-450 activity by the brain dopaminergic system

2006 ◽  
Vol 16 ◽  
pp. S234-S235
Author(s):  
J. Wójcikowski ◽  
K. Gołembiowska ◽  
W.A. Danie
Keyword(s):  
Dopaminergic System ◽  
Cytochrome P 450 ◽  
The Brain

scholarly journals Influence of dopaminergic system gene polymorphisms on mixed amphetamine-type stimulants and opioid dependence in Malaysian Malays

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Abu Bakar Ruzilawati ◽  
Mohd Sidek Deeza-Syafiqah ◽  
Imran Ahmad ◽  
Shaharum Shamsuddin ◽  
Siew Hua Gan ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Opioid Dependence ◽  
Dopaminergic System

scholarly journals Effect of the brain dopaminergic system in the muricide induced by thiamine deficiency

1984 ◽  
Vol 36 ◽  
pp. 163
Author(s):  
Yuji Abe ◽  
Takeshi Tadano ◽  
Kensuke Kisara ◽  
Takahiko Suzuki
Keyword(s):  
Thiamine Deficiency ◽  
Dopaminergic System ◽  
The Brain

scholarly journals Putrescine, a source of γ-aminobutyric acid in the adrenal gland of the rat

1988 ◽  
Vol 251 (2) ◽  
pp. 559-562 ◽  
Author(s):  
P C Caron ◽  
L J Cote ◽  
L T Kremzner
Keyword(s):  
Adrenal Gland ◽  
Diamine Oxidase ◽  
Cell Metabolism ◽  
Turnover Time ◽  
Oxidase Inhibitor ◽  
Aminobutyric Acid ◽  
Gamma Aminobutyric Acid ◽  
Gaba Concentration ◽  
The Brain

Putrescine is the major source of gamma-aminobutyric acid (GABA) in the rat adrenal gland. Diamine oxidase, and not monoamine oxidase, is essential for GABA formation from putrescine in the adrenal gland. Aminoguanidine, a diamine oxidase inhibitor, decreases the GABA concentration in the adrenal gland by more than 70% after 4 h, and almost to zero in 24 h. Studies using [14C]putrescine confirm that [14C]GABA is the major metabolite of putrescine in the adrenal gland. Inhibition of GABA transaminase by amino-oxyacetic acid does not change the GABA concentration in the adrenal gland, as compared with the brain, where the GABA concentration rises. With aminoguanidine, the turnover time of GABA originating from putrescine in the adrenal gland is 5.6 h, reflecting a slower rate of GABA metabolism compared with the brain. Since GABA in the adrenal gland is almost exclusively derived from putrescine, the role of GABA may relate to the role of putrescine as a growth factor and regulator of cell metabolism.

scholarly journals Fatal Human herpesvirus 1 (HHV-1) infection in captive marmosets (Callithrix jacchus and Callithrix penicillata) in Brazil: clinical and pathological characterization

2014 ◽  
Vol 34 (11) ◽  
pp. 1109-1114 ◽  
Author(s):  
Renata A. Casagrande ◽  
Cláudio S. Pannuti ◽  
Cristina Kanamura ◽  
Wilton S. Freire ◽  
André Grespan ◽  
...  
Keyword(s):  
Adrenal Gland ◽  
Clinical Signs ◽  
Human Herpesvirus ◽  
Callithrix Jacchus ◽  
Sao Paulo ◽  
Pcr Analysis ◽  
São Paulo ◽  
Facial Skin ◽  
Herpesvirus 1 ◽  
The Brain

Fatal Human herpesvirus 1 (HHV-1) was diagnosed in 12 captive marmosets (Callithrix jacchus and Callithrix penicillata) from metropolitan region of São Paulo, São Paulo State. Clinical signs were variable among the cases, but most affected marmosets presented signs associated with viral epithelial replication: oral, lingual and facial skin ulcers and hypersalivation, and viral replication in the central nervous system: prostration, seizure and aggressive behavior. Consistent microscopic findings were diffuse mild to severe nonsuppurative necrotizing meningoencephalitis with gliosis, vasculitis and neuronal necrosis. Additionally, in the brain, oral cavity, skin, adrenal gland and myoenteric plexus intranuclear inclusion bodies were present. Immunohistochemistry confirmed the presence of the HHV-1 antigen in association with lesions in the brain, oral and lingual mucosa, facial skin, adrenal gland and myoenteric plexus. HHV-1-specific polymerase chain reaction (PCR) analysis of the brain was carried out and the virus was detected in 7/8 infected marmosets. It is concluded that HHV-1 causes widespread fatal infection in marmosets.

scholarly journals Correlation between behavioral alterations and dopamine changes in mice experimentally infected with Toxoplasma gondii

2020 ◽  
pp. 39-57
Author(s):  
Ahmed Ossamy Al-Namroty ◽  
Raafat Mohamed Shaapan ◽  
Amal Abdul-Rasheed El-Moamly ◽  
Eman Moustafa Al-Hamshary
Keyword(s):  
Toxoplasma Gondii ◽  
Open Field ◽  
Infected Animal ◽  
Dopaminergic System ◽  
Behavioral Alterations ◽  
Infected Female ◽  
Board Test ◽  
Hole Board ◽  
Hole Board Test ◽  
The Brain

The mechanism of the parasite to induce alterations in host behavior is suggested due to changes in the dopaminergic system. This study aims to clarify the effects of latent toxoplasmosis on infected mice's behavior and to assess the dopamine neurotransmitter in their brains. Experimental infection with Toxoplasma gondii (T. gondii) and monitoring of behavioral alterations in mice using open field and hole-board tests were carried. Mice were sacrificed, then brains histo-pathologically and neuro-chemically assessed. Open field test revealed a decrease in locomotion in both infected mice genders, whereas the hole-board test displayed an increased level of exploration only by infected female mice. Significant changes in the dopamine concentration in the brain with regard to status of infection were detected. The results suggest an association between T. gondii infection and changes in the behavior. Neuromodulators may represent an ideal mechanism by which T. gondii, at least in part of the expression, can influence the behavior of the infected animal or even human host.

Sign in / Sign up

Export Citation Format

Share Document