Hunting for bis-bibenzyls in Primula veris subsp. macrocalyx (Bunge) Lüdi: Organ-specific accumulation and cytotoxic activity

2021 ◽  
Vol 44 ◽  
pp. 90-97
Author(s):  
Danka Bukvicki ◽  
Nataliya K. Kovtonyuk ◽  
Anton A. Legin ◽  
Bernhard K. Keppler ◽  
Lothar Brecker ◽  
...  
2008 ◽  
Vol 3 (8) ◽  
pp. 1934578X0800300 ◽  
Author(s):  
Tshering D. Bhutia ◽  
Karin M. Valant-Vetschera

A new accession of Artemisia dracunculus L., originating from Kyrgyzstan, has been analyzed for the first time regarding organ-specific accumulation of lipophilic compounds. Differences were found between leaves, stems, and inflorescences. Exudates obtained from aerial parts yielded only flavanones (eriodictyol, naringenin and their methyl ethers), while the coumarins herniarin and scoparone and biosynthetically unrelated isocoumarins (artemidin, dracumerin) were found to be tissue components. The chemosystematic significance of observed accumulation tendencies is shortly discussed, and other chemodiversity aspects are briefly addressed.


Planta Medica ◽  
1992 ◽  
Vol 58 (S 1) ◽  
pp. 692-693 ◽  
Author(s):  
G. Brader ◽  
G. Wurz ◽  
H. Greger

Planta ◽  
1993 ◽  
Vol 190 (4) ◽  
Author(s):  
Pascal Gantet ◽  
Judy Brangeon ◽  
Jeanine Grisvard ◽  
Michel Dron

2009 ◽  
Vol 4 (3) ◽  
pp. 1934578X0900400 ◽  
Author(s):  
Karin M. Valant-Vetschera ◽  
Tshering Doma Bhutia ◽  
Eckhard Wollenweber

Several new accessions of the genus Primula and of the closely related Cortusa matthioli have been studied for their exudate flavonoid profiles. Unsubstituted flavone, 5-hydroxy-, 2′-hydroxyflavone and 5,2′-dihydroxyflavone were found as main components. Several other rather unusual substitution patterns were also found. 8- O-Substituted flavones appear to be accumulated more often than 6- O-substituted products. Chalcones with corresponding substitution patterns were of scattered occurrence, while flavanones could so far not be detected in exudates of Primula species. The distribution of externally accumulated flavonoids, including literature data, is related to current taxonomic views on the infrageneric grouping of Primula and related taxa. Organ-specific accumulation, biosynthetic and chemosystematic aspects are briefly addressed.


2010 ◽  
Vol 5 (7) ◽  
pp. 1934578X1000500 ◽  
Author(s):  
Grace Leontine Nwabouloun Djoufack ◽  
Karin M. Valant-Vetschera ◽  
Johann Schinnerl ◽  
Lothar Brecker ◽  
Eberhard Lorbeer ◽  
...  

Stem bark, roots, leaves and fruits of Pentadesma grandifolia Baker f. (Clusiaceae) have been analyzed for the presence of xanthones, biflavonoids and triterpenoids. Isolated and identified structures include the xanthones cowagarcinone B (1) and α-mangostin (2), further the two biflavanones 3,8″-binaringenin (3) and the corresponding 3,6″-binaringenin (4), which is here reported as natural constituent for the first time. Structures were determined by NMR and mass spectrometry, as well as by 13C-NMR CSEARCH and SPECINFO database systems. The triterpenes lupeol (5), ß-amyrin (6) and betulin (7) were also encountered. Compounds 2 - 4 exhibited antifungal activity against Cladosporium sphaerospermum. Results are discussed in context to organ-specific accumulation and to other bioactivities that may relate to the ethnomedicinal uses of this species.


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