scholarly journals Arterial endothelial cytokines guide extravillous trophoblast invasion towards spiral arteries; an in-vitro study with the trophoblast cell line ACH-3P and female non-uterine endothelial cells

Placenta ◽  
2016 ◽  
Vol 38 ◽  
pp. 49-56 ◽  
Author(s):  
Gregor Weiss ◽  
Berthold Huppertz ◽  
Monika Siwetz ◽  
Ingrid Lang ◽  
Gerit Moser
2010 ◽  
Vol 62 (3) ◽  
pp. 531-538 ◽  
Author(s):  
Milica Jovanovic ◽  
Tamara Kovacevic ◽  
Ivana Stefanoska ◽  
Ljiljana Vicovac

Embryonic development up to the blastocyst stage, implantation into the uterine wall and the development of the functional placenta are steps crucial for the establishment of normal pregnancy. Specific cells of the placenta, the trophoblast cells, invade the uterine stroma and spiral arteries, adapting them to pregnancy. Interleukin-6 is present in the human endometrium during the receptive phase and early pregnancy. Trophoblasts also produce IL-6, which was found to stimulate trophoblast invasion and migration in vitro. Here we show that the activity of MMP-9 may contribute to the observed increased invasion. In addition, in the HTR-8/SVneo trophoblast cell line IL-6 increases cell proliferation. .


Placenta ◽  
2013 ◽  
Vol 34 (9) ◽  
pp. A47
Author(s):  
Gregor Weiss ◽  
Ingrid Lang ◽  
Monika Siwetz ◽  
Berthold Huppertz ◽  
Gerit Moser

2018 ◽  
Vol 295 ◽  
pp. S141
Author(s):  
M.G. Hinojosa ◽  
D. Gutierrez-Praena ◽  
A.I. Prieto ◽  
L. Espinar-López ◽  
A.M. Cameán ◽  
...  

2005 ◽  
Vol 31 (3) ◽  
pp. 341-360 ◽  
Author(s):  
Gregory A. Day ◽  
Mark D. Hoover ◽  
Aleksandr B. Stefaniak ◽  
Robert M. Dickerson ◽  
Eric J. Peterson ◽  
...  

2015 ◽  
Vol 12 (3) ◽  
pp. 351
Author(s):  
Risa Hamada ◽  
Ryota Matsuzaki ◽  
Hiromi Takenoya ◽  
Mariko Kurotsu ◽  
Emiyu Ogawa ◽  
...  

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