The Effect of Vitamin D Supplementation on Pain, Mood, Depression, and Strength in Patients with Spinal Cord Injury

PM&R ◽  
2016 ◽  
Vol 8 (9) ◽  
pp. S153 ◽  
Author(s):  
Thornton G. Williams ◽  
Reza Ehsanian ◽  
Kazuko L. Shem ◽  
Jerry Wright ◽  
Linda Isaac ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Vitamin D Supplementation ◽  
Cord Injury ◽  
Mood Depression

scholarly journals Effect of 12-Week Vitamin D Supplementation on 25[OH]D Status and Performance in Athletes with a Spinal Cord Injury

Nutrients ◽  
2016 ◽  
Vol 8 (10) ◽  
pp. 586 ◽  
Author(s):  
Joelle Flueck ◽  
Max Schlaepfer ◽  
Claudio Perret
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Vitamin D Supplementation ◽  
Cord Injury ◽  
And Performance

scholarly journals Venous Thromboembolism is Associated With Lack of Vitamin D Supplementation in Patients With Spinal Cord Injury and Low Vitamin D Levels

PM&R ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 125-134
Author(s):  
Reza Ehsanian ◽  
Molly A. Timmerman ◽  
Jerry M. Wright ◽  
Stephen McKenna ◽  
Ben Dirlikov ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Venous Thromboembolism ◽  
Vitamin D Supplementation ◽  
Vitamin D Levels ◽  
Cord Injury

scholarly journals Vitamin D supplementation in chronic spinal cord injury (VitD-SCI): study protocol for a randomised controlled trial

BMJ Open ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. e053951
Author(s):  
Anneke Hertig-Godeschalk ◽  
Martin W G Brinkhof ◽  
Anke Scheel-Sailer ◽  
Claudio Perret ◽  
Andreas Jenny ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Vitamin D Insufficiency ◽  
Vitamin D Supplementation ◽  
Optimal Dosage ◽  
Vitamin D Status ◽  
Mineral Density ◽  
Chronic Spinal Cord Injury ◽  
Cord Injury

IntroductionVitamin D insufficiency, a vitamin D status or serum 25(OH)D concentration of ≤75 nmol/L, is highly prevalent in individuals with a spinal cord injury (SCI). Vitamin D is important for the functioning of the musculoskeletal, immune and respiratory systems, which are relevant determinants of secondary health conditions in SCI. An insufficiency should be treated with vitamin D supplementation. However, there is a lack of evidence regarding the optimal dosage and duration of vitamin D supplementation for individualised and long-term management of the vitamin D status in the context of SCI. This paper presents the protocol for the vitamin D supplementation in chronic spinal cord injury (VitD-SCI) trial that aims to investigate the effect of a 12-month intake of vitamin D supplementation on vitamin D status as well as on several secondary parameters among individuals with a chronic SCI.Methods and analysesThe VitD-SCI trial is a randomised, placebo-controlled, double-blinded, parallel-group, superiority trial, conducted at the Swiss Paraplegic Centre. A total of 45 participants living with an SCI for at least 3 years (chronic SCI) and a vitamin D insufficiency at the first study visit, will be randomly assigned to one of three intervention groups. Participants receive either a monthly dosage of 24 000 IU or 48 000 IU vitamin D or a placebo for 12 months. Measurements taking place every 3 months include the assessment of vitamin D status (primary outcome) as well as bone mineral density, handgrip strength, fatigue, mood, pain and pressure injuries (secondary outcomes). Safety and tolerance of vitamin D supplementation will also be evaluated.Ethics and disseminationThe Swiss Ethics Committee for Northwest/Central Switzerland (EKNZ, 2020–01493) and the Swiss Agency for Therapeutic Products (Swissmedic, 2020DR3150) approved this study. Findings will be disseminated through peer-reviewed publications.Trial registration numbersNCT04652544 and SNCTP000004032.

Effect of Vitamin D Supplementation on 25(OH)D Status in Elite Athletes With Spinal Cord Injury

2019 ◽  
Vol 29 (1) ◽  
pp. 18-23 ◽  
Author(s):  
Kelly Pritchett ◽  
Robert C. Pritchett ◽  
Lauren Stark ◽  
Elizabeth Broad ◽  
Melissa LaCroix
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Maintenance Dose ◽  
Elite Athletes ◽  
Handgrip Strength ◽  
Vitamin D Supplementation ◽  
Muscle Performance ◽  
Cord Injury ◽  
Sufficient Vitamin

Recent studies suggest that a substantial proportion of athletes with spinal cord injury have insufficient 25(OH) vitamin D (25(OH)D) status, which may be associated with decreased muscle strength. This study consisted of two parts: (a) to examine the effects of a 12- to 16-week vitamin D3 supplementation protocol on 25(OH)D concentration and (b) to determine whether subsequent 25(OH)D status impacts muscle performance in elite athletes with spinal cord injury. Thirty-four members (age: 33 ± 15 years, weight: 69.6 ± 28.2 kg, and height: 170.2 ± 25.4 cm) of the U.S. and Canadian Paralympic program participated in the study. 25(OH)D concentrations and performance measures (handgrip strength and 20-m wheelchair sprint) were assessed pre- and postsupplementation. Participants were assigned a vitamin D3 supplementation protocol based on initial 25(OH)D concentrations. Participants with deficient 25(OH)D status (<50 nmol/L) received 50,000 IU/week for 8 weeks, and participants with insufficient status (50–75 nmol/L) received 35,000 IU/week for 4 weeks, after which both received a maintenance dose of 15,000 IU/week. Participants with sufficient status (>75 nmol/L) received the maintenance dose of 15,000 IU/week. 25(OH)D concentrations increased significantly (p < .001; 66.3 ± 24.3 nmol/L and 111.3 ± 30.8 nmol/L pre- and postsupplementation, respectively). About 26% of athletes had sufficient 25(OH)D concentrations presupplementation, and 91% had sufficient concentrations postsupplementation. About 62% of participants improved handgrip strength postsupplementation with no change in 20-m wheelchair sprint performance. The supplementation protocol was effective for achieving sufficient vitamin D concentrations in elite athletes with spinal cord injury.

Effect of Vitamin D Supplementation on 25(OH)D Status in Elite Athletes with Spinal Cord Injury

2017 ◽  
Vol 49 (5S) ◽  
pp. 678
Author(s):  
Kelly L. Pritchett ◽  
Robert C. Pritchett ◽  
Lauren Stark ◽  
Elizabeth Broad ◽  
Melissa LaCroix
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Elite Athletes ◽  
Vitamin D Supplementation ◽  
Cord Injury

scholarly journals Creatine or vitamin D supplementation in individuals with a spinal cord injury undergoing resistance training: A double-blinded, randomized pilot trial

2017 ◽  
Vol 41 (4) ◽  
pp. 471-478 ◽  
Author(s):  
Samuel Amorim ◽  
Vitor Hugo Teixeira ◽  
Rui Corredeira ◽  
Maria Cunha ◽  
Bruno Maia ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Resistance Training ◽  
Pilot Trial ◽  
Vitamin D Supplementation ◽  
Cord Injury ◽  
Double Blinded

scholarly journals High prevalence of vitamin D deficiency in patients with spinal cord injury: a 1 year longitudinal study

2014 ◽  
Vol 73 (OCE1) ◽  
Author(s):  
S. Wong ◽  
I. Gainullina ◽  
A. Graham ◽  
S. P. Hirani ◽  
A. Forbes
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Longitudinal Study ◽  
Vitamin D Deficiency ◽  
Cord Injury ◽  
High Prevalence

Autonomic cardiovascular dysfunction and vitamin D deficiency in pediatric spinal cord injury

2013 ◽  
Vol 6 (1) ◽  
pp. 45-52 ◽  
Author(s):  
Kathy Zebracki ◽  
Miriam Hwang ◽  
Pamela L. Patt ◽  
Lawrence C. Vogel
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Vitamin D Deficiency ◽  
Cardiovascular Dysfunction ◽  
Cord Injury ◽  
Pediatric Spinal Cord Injury

Vitamin D profile of patients with spinal cord injury and post-stroke hemiplegia: All in the same boat

2016 ◽  
Vol 29 (2) ◽  
pp. 205-210 ◽  
Author(s):  
Ilke Coskun Benlidayi ◽  
Sibel Basaran ◽  
Gulsah Seydaoglu ◽  
Rengin Guzel
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Post Stroke ◽  
Cord Injury
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