scholarly journals Venous Thromboembolism is Associated With Lack of Vitamin D Supplementation in Patients With Spinal Cord Injury and Low Vitamin D Levels

PM&R ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 125-134
Author(s):  
Reza Ehsanian ◽  
Molly A. Timmerman ◽  
Jerry M. Wright ◽  
Stephen McKenna ◽  
Ben Dirlikov ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Venous Thromboembolism ◽  
Vitamin D Supplementation ◽  
Vitamin D Levels ◽  
Cord Injury

The Effect of Vitamin D Supplementation on Pain, Mood, Depression, and Strength in Patients with Spinal Cord Injury

PM&R ◽  
2016 ◽  
Vol 8 (9) ◽  
pp. S153 ◽  
Author(s):  
Thornton G. Williams ◽  
Reza Ehsanian ◽  
Kazuko L. Shem ◽  
Jerry Wright ◽  
Linda Isaac ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Vitamin D Supplementation ◽  
Cord Injury ◽  
Mood Depression

Re: A Descriptive Study of Vitamin D Levels in Persons With Acute Spinal Cord Injury

PM&R ◽  
2010 ◽  
Vol 2 (9) ◽  
pp. 872-872
Author(s):  
James Crew ◽  
Pooja Rathi ◽  
Stephen L. McKenna ◽  
Jackie Garcia
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Descriptive Study ◽  
Acute Spinal Cord Injury ◽  
Vitamin D Levels ◽  
Cord Injury

scholarly journals Low vitamin D levels are independent predictors of 1-year worsening in physical function in people with chronic spinal cord injury: a longitudinal study

Spinal Cord ◽  
2018 ◽  
Vol 56 (5) ◽  
pp. 494-501 ◽  
Author(s):  
Arcangelo Barbonetti ◽  
Settimio D’Andrea ◽  
Alessio Martorella ◽  
Giorgio Felzani ◽  
Sandro Francavilla ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Longitudinal Study ◽  
Physical Function ◽  
Chronic Spinal Cord Injury ◽  
Vitamin D Levels ◽  
Cord Injury

A Descriptive Study on Vitamin D Levels in Individuals With Spinal Cord Injury in an Acute Inpatient Rehabilitation Setting

PM&R ◽  
2010 ◽  
Vol 2 (3) ◽  
pp. 202-208 ◽  
Author(s):  
Gregory A. Nemunaitis ◽  
Melvin Mejia ◽  
Jennifer A. Nagy ◽  
Tova Johnson ◽  
John Chae ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Inpatient Rehabilitation ◽  
Descriptive Study ◽  
Vitamin D Levels ◽  
Cord Injury

scholarly journals Effect of 12-Week Vitamin D Supplementation on 25[OH]D Status and Performance in Athletes with a Spinal Cord Injury

Nutrients ◽  
2016 ◽  
Vol 8 (10) ◽  
pp. 586 ◽  
Author(s):  
Joelle Flueck ◽  
Max Schlaepfer ◽  
Claudio Perret
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Vitamin D Supplementation ◽  
Cord Injury ◽  
And Performance

Lower Vitamin D Levels Are Associated With Depression in People With Chronic Spinal Cord Injury

2017 ◽  
Vol 98 (5) ◽  
pp. 940-946 ◽  
Author(s):  
Arcangelo Barbonetti ◽  
Francesca Cavallo ◽  
Settimio D'Andrea ◽  
Mario Muselli ◽  
Giorgio Felzani ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Chronic Spinal Cord Injury ◽  
Vitamin D Levels ◽  
Cord Injury ◽  
Lower Vitamin

scholarly journals Factors related to decreased vitamin D levels in men with spinal cord injury living in a subtropical region

2018 ◽  
Vol 28 (2) ◽  
pp. 28381
Author(s):  
Mauricio Sprenger Bassuino ◽  
Elisa Lettnin Kaminski ◽  
Laís Oliveira Garcia ◽  
Rafael Linden ◽  
Marina Venzon Antunes ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Parathyroid Hormone ◽  
Linear Regression ◽  
Sun Exposure ◽  
Minimum Wages ◽  
Vitamin D Levels ◽  
Cord Injury ◽  
The Mean

AIMS: To evaluate the levels of vitamin D, parathyroid hormone and calcium in individuals with spinal cord injury and to identify related factors.METHODS: A cross-sectional study included men with spinal cord injury, living in the South Region of Brazil. A questionnaire was applied to evaluate socioeconomic data, life habits and health. The time elapsed since the spinal cord injury was considered. Vitamin D was evaluated in plasma via liquid chromatography; calcium and PTH were measured in serum by a colorimetric method and electrochemiluminescence respectively. For data analysis, linear regression and chi-square test were utilized. Values of p<0.05 were considered significant.  RESULTS: The study included 39 paraplegic or tetraplegic men with spinal cord injury. The mean age was 35.52±9.78 years, and the mean time since injury was 6.09±5.55 years. The mean biochemical levels were: 19.0 ±6.98 ng/mL for vitamin D; 9.54±0.52 mg/dL for total calcium; and 34.81±10.84 pg/mL for parathyroid hormone. Individuals with sun exposure for more than two hours daily had higher vitamin D levels than those exposed up to one hour per day (p=0.001). Linear regression identified an inverse relationship between lesion time and vitamin D levels (regression coefficient: -0.424; p=0.029), while the other parameters did not show significant differences regarding the time elapsed since the lesion. Subjects with income above four minimum wages had higher vitamin D values (mean 25.67±5.45 ng/mL) when compared to those with income up to four minimum wages (mean 18.43±6.79 ng/mL) (p=0.021). CONCLUSIONS: Levels of vitamin D were inversely correlated to the time elapsed since the spinal cord injury, probably due to insufficient sun exposure resulting from prolonged limitation of mobility. In addition, lower levels of vitamin D were associated to lower income. These factors may aggravate bone loss associated with decreased mobility resulting from spinal cord injury.

scholarly journals Vitamin D levels in persons with traumatic spinal cord injury: a multicentre observational study

2021 ◽  
Vol 8 (8) ◽  
pp. 1164
Author(s):  
Sucheta Saha ◽  
Sandeep K. Gupt ◽  
Nonica Laisram ◽  
Ummatul Siddique ◽  
Simin Rahman
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Vitamin D Deficiency ◽  
High Rate ◽  
Traumatic Spinal Cord Injury ◽  
Vitamin D Levels ◽  
Cord Injury ◽  
25 Oh Vitamin D

Background: According to the published literature, Vitamin D deficiency is prevalent in spinal cord injury (SCI). Many studies were done earlier to find out different factors which predispose the SCI population to the risk of vitamin deficiency, but correlation with any such factor is still uncertain. Studies from India are scarce. The present study was conducted in view of this lacuna in existing knowledge in India and in the developing countries, to observe the levels of Vitamin D in traumatic SCI patients admitted for rehabilitation.Methods: In this prospective, observational, multicentre study, all patients admitted consecutively in the three study centres, satisfying the selection criteria were included. The level of 25-OH Vitamin D was assessed by Chemiluminescence procedure. Vitamin D level <20 ng/ml was taken as deficient, 20-29ng/ml as insufficient, ≥30 ng/ml was the optimum and ≥150 ng/ml was taken as toxic level.Results: Among 56 patients of traumatic spinal cord injury who were included in the study, having mean age of 32.32±11.82 years, only 14 (25%) were having optimum Vitamin D level. 25 (45%) subjects were deficient in Vitamin D, whereas 16 (28%) were having insufficient levels. One subject was found to have toxic level of Vitamin D (156 ng/ml). No differences of Vitamin D levels were observed between demographic and clinical groups.Conclusions: Although a high rate of Vitamin D deficiency was encountered in SCI individuals, the role of different factors causing Vitamin D deficiency remains unproven. Also the amount of Vitamin D required to forestall insufficiency is still unknown, indicating a necessity for more studies with well-defined outcome measures.  

scholarly journals Vitamin D supplementation in chronic spinal cord injury (VitD-SCI): study protocol for a randomised controlled trial

BMJ Open ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. e053951
Author(s):  
Anneke Hertig-Godeschalk ◽  
Martin W G Brinkhof ◽  
Anke Scheel-Sailer ◽  
Claudio Perret ◽  
Andreas Jenny ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Vitamin D Insufficiency ◽  
Vitamin D Supplementation ◽  
Optimal Dosage ◽  
Vitamin D Status ◽  
Mineral Density ◽  
Chronic Spinal Cord Injury ◽  
Cord Injury

IntroductionVitamin D insufficiency, a vitamin D status or serum 25(OH)D concentration of ≤75 nmol/L, is highly prevalent in individuals with a spinal cord injury (SCI). Vitamin D is important for the functioning of the musculoskeletal, immune and respiratory systems, which are relevant determinants of secondary health conditions in SCI. An insufficiency should be treated with vitamin D supplementation. However, there is a lack of evidence regarding the optimal dosage and duration of vitamin D supplementation for individualised and long-term management of the vitamin D status in the context of SCI. This paper presents the protocol for the vitamin D supplementation in chronic spinal cord injury (VitD-SCI) trial that aims to investigate the effect of a 12-month intake of vitamin D supplementation on vitamin D status as well as on several secondary parameters among individuals with a chronic SCI.Methods and analysesThe VitD-SCI trial is a randomised, placebo-controlled, double-blinded, parallel-group, superiority trial, conducted at the Swiss Paraplegic Centre. A total of 45 participants living with an SCI for at least 3 years (chronic SCI) and a vitamin D insufficiency at the first study visit, will be randomly assigned to one of three intervention groups. Participants receive either a monthly dosage of 24 000 IU or 48 000 IU vitamin D or a placebo for 12 months. Measurements taking place every 3 months include the assessment of vitamin D status (primary outcome) as well as bone mineral density, handgrip strength, fatigue, mood, pain and pressure injuries (secondary outcomes). Safety and tolerance of vitamin D supplementation will also be evaluated.Ethics and disseminationThe Swiss Ethics Committee for Northwest/Central Switzerland (EKNZ, 2020–01493) and the Swiss Agency for Therapeutic Products (Swissmedic, 2020DR3150) approved this study. Findings will be disseminated through peer-reviewed publications.Trial registration numbersNCT04652544 and SNCTP000004032.

Low Vitamin D Levels in Persons with Spinal Cord Injury and Increased Incidence of Venous Thromboembolic Events During Acute Inpatient and Rehabilitation Stay

PM&R ◽  
2013 ◽  
Vol 5 ◽  
pp. S140-S140 ◽  
Author(s):  
Molly A. Timmerman ◽  
James Crew ◽  
Kazuko Shem ◽  
Min Kim ◽  
Stephanie A. Kolakowsky-Hayner ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Vitamin D ◽  
Spinal Cord Injury ◽  
Thromboembolic Events ◽  
Vitamin D Levels ◽  
Cord Injury ◽  
Venous Thromboembolic Events ◽  
Venous Thromboembolic
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