Polymeric nanocapsules as a binder system for fluidized bed granules: Influence on particle growth behavior, flow, compaction properties, and drug release

2021 ◽  
Vol 385 ◽  
pp. 327-335
Author(s):  
Edilene Gadelha de Oliveira ◽  
Rafaela Santos de Oliveira ◽  
Martina Ventura Konrad ◽  
Nathalie Jung ◽  
Maike Windbergs ◽  
...  
Keyword(s):  
Drug Release ◽  
Fluidized Bed ◽  
Particle Growth ◽  
Growth Behavior ◽  
Binder System ◽  
Polymeric Nanocapsules ◽  
Compaction Properties

Effect of Process Variables on Efficiency and Particle Growth of Spilanthes oleracea Seeds Coating

2010 ◽  
Vol 660-661 ◽  
pp. 419-425 ◽  
Author(s):  
C.M.L. Costa ◽  
L.J.G. Faria ◽  
Cristina dos Santos Rocha Sandra
Keyword(s):  
Fluidized Bed ◽  
Flow Rate ◽  
Particle Growth ◽  
Process Variables ◽  
Relative Growth ◽  
Coating Efficiency ◽  
Fluidized Bed Coating ◽  
Common Technique ◽  
Coating Suspension ◽  
Granule Growth

The coating of vegetable seeds is a very common technique, mainly for the species which have small seeds. One of its functions is to increase the seed size to direct sowing. In the present study the coating of Spilanthes oleracea L. seeds with a polymeric suspension in fluidized bed was analyzed. The effects of process variables on the coating efficiency of top-spray fluidized bed coating were evaluated. The independent variables studied were the flow rate of coating suspension and the air mass flow. The quantification for the entrance variables influence on the coating efficiency and granule growth, as well as the identification of optimal conditions were made by means of an experiment factorial design technique. Polynomial models for the responses: efficiency and relative growth of the particles were deduced. The highest coating efficiency was achieved at a high flow rate of coating suspension.

scholarly journals Influence of drying conditions on the acacia gum particle growth in fluidized bed agglomeration: in-line monitoring of particle size

2018 ◽  
Author(s):  
Juliana G Rosa ◽  
R. F. Nascimento ◽  
K. Andreola ◽  
O. P. Taranto
Keyword(s):  
Particle Size ◽  
Fluidized Bed ◽  
Particle Growth ◽  
Spatial Filter ◽  
Important Food ◽  
Process Yield ◽  
Size Monitoring ◽  
Acacia Gum ◽  
Bed Agglomeration ◽  
Drying Conditions

Acacia gum is an important food emulsifier that presents poor instant properties which can be improved by fluidized bed agglomeration. This study investigated the influence of drying conditions on particle growth kinetics using an in-line particle size monitoring by spatial filter velocimetry. The drying conditions varied according to the binder flow rate and the fluidizing air temperature. The particle growth kinectis showed drying conditions dependence. At mild drying conditions the growth rate and the process yield were higher. The in-line particle size monitoring was useful to observe the influence of the drying conditions on the growth kinetics.Keywords: fluidized bed agglomeration; acacia gum; particle growth kinectis; in-line monitoring.  

Loading A Drug on Contact Lenses Using Polymeric Nanocapsules: Effects on Drug Release, Transparency, and Ion Permeability

2017 ◽  
Vol 17 (12) ◽  
pp. 9286-9294 ◽  
Author(s):  
T Katzer ◽  
P. S Chaves ◽  
A. R Pohlmann ◽  
S. S Guterres ◽  
R. C. R Beck
Keyword(s):  
Drug Release ◽  
Contact Lenses ◽  
Ion Permeability ◽  
Polymeric Nanocapsules

Optimization of the supercritical fluidized bed process for sirolimus coating and drug release

2020 ◽  
Vol 589 ◽  
pp. 119809
Author(s):  
Tingting Chen ◽  
Liuyi Liu ◽  
Lei Zhang ◽  
Tiejun Lu ◽  
Ravenna L. Matos ◽  
...  
Keyword(s):  
Drug Release ◽  
Fluidized Bed ◽  
Fluidized Bed Process

Silicon particle growth in a fluidized-bed reactor

AIChE Journal ◽  
1987 ◽  
Vol 33 (5) ◽  
pp. 784-791 ◽  
Author(s):  
George Hsu ◽  
Naresh Rohatgi ◽  
John Houseman
Keyword(s):  
Fluidized Bed ◽  
Silicon Particle ◽  
Fluidized Bed Reactor ◽  
Particle Growth
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