Stromal tumors of the lower female genital tract: Histogenetic, morphological and immunohistochemical similarities with the “Benign Spindle Cell Tumors of the Mammary Stroma”

2007 ◽  
Vol 203 (11) ◽  
pp. 827-829 ◽  
Author(s):  
Gaetano Magro
Keyword(s):  
Genital Tract ◽  
Spindle Cell ◽  
Female Genital Tract ◽  
Stromal Tumors ◽  
Spindle Cell Tumors ◽  
Female Genital

Primary ovarian synovial sarcoma

2021 ◽  
Vol 14 (11) ◽  
pp. e244756
Author(s):  
Muhammad Amin ur Rahman ◽  
Khalid Al Wadi ◽  
Al Nuqaydan ◽  
Raghad Tallab
Keyword(s):  
Differential Diagnosis ◽  
Synovial Sarcoma ◽  
Molecular Pathology ◽  
Genital Tract ◽  
Spindle Cell ◽  
Female Genital Tract ◽  
Rare Occurrence ◽  
Spindle Cell Tumours ◽  
Spindle Cell Tumour ◽  
Female Genital

Synovial sarcoma (SS) has a rare occurrence in the female genital tract. Only three prior reports of primary ovarian sarcoma could be retrieved after a thorough literature review. We are reporting a case of primary ovarian SS in a young woman. The tumour showed monophasic spindle cell morphology, and there was a wide list of differential diagnosis to consider. We confirmed the diagnosis by cytogenetics Flourescent Insitu Hybridisation (FISH) technique to identify the classical translocation. The diagnosis of this disease can be challenging especially if the tumour is of monophasic type. Morphology and immunohistochemistry are not enough to confirm the diagnosis in many cases. A confirmatory molecular pathology test is paramount. We have discussed the differential diagnosis of spindle cell tumours in ovary. We suggest that SS should be in the differential diagnoses when facing any atypical spindle cell tumour in the ovary. Molecular pathology techniques can help to confirm the diagnosis.

scholarly journals Synchronous primary ovarian sex cord tumor and endometrial cancer

2016 ◽  
Author(s):  
S. A. Iqbal ◽  
H. Shukla ◽  
V. Jain ◽  
S. Giri ◽  
R. Sekhon ◽  
...  
Keyword(s):  
Genital Tract ◽  
Ovarian Tumor ◽  
Early Stage ◽  
Female Genital Tract ◽  
Low Grade ◽  
Primary Tumors ◽  
Stromal Tumors ◽  
Gynaecological Tumours ◽  
Sex Cord Stromal Tumors ◽  
Female Genital

Synchronous primary tumors of female genital tract are rare with a rate of about 0.7-1.8% of all gynaecological tumours. Most common primary tumours presenting as synchronous lesions are ovary and endometrium. However, sex cord stromal tumors are rare variety of primary ovarian tumor and synchronous with endometrium is even much rarer. These tumors are detected usually in younger, overweight, nulliparous and perimenopausal female. Synchronous primary tumors of endometrium and ovary have a better prognosis than the either of above alone because these are usually low grade and diagnosed at early stage. We present a report of four cases of synchronous endometrial and sex cord stromal tumors of ovary.

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