Subjective Cognitive Complaints and Objective Cognitive Impairment in Hoarding Disorder

ABSTRACT:Background:Although cognitive deficits are frequent in multiple sclerosis (MS), screening for them with tools such as the Montreal Cognitive Assessment (MoCA) test is usually not performed unless there is a subjective complaint. The Multiple Sclerosis Neuropsychological Questionnaire (MSNQ) is among the instruments most commonly used to assess self-reported subjective complaints in MS. Nonetheless, it does not always accurately reflect cognitive status; many patients with cognitive deficits thus fail to receive appropriate referral for detailed neuropsychological evaluation. The objective of this study was to examine the validity of the MoCA test to detect the presence of objective cognitive deficits among patients with MS without subjective complaints using the Minimal Assessment of Cognitive Function in MS (MACFIMS) as the gold standard.Methods:The sample included 98 patients who were recruited from a university hospital MS clinic. The MSNQ was used to select patients without subjective cognitive complaints who also completed the MACFIMS, MoCA test and MSQOL-54.Results:23.5% of patients without subjective cognitive complaints had evidence of objective cognitive impairment on the MACFIMS (z score < -1.5 on two or more tests). The MoCA had a sensitivity of 87% and a specificity of 68% for detecting objective cognitive impairment in this patient population using a cut-off score of 27.Conclusion:A significant proportion of patients without self-reported cognitive impairment do have evidence of cognitive deficits on more exhaustive cognitive assessment. The MoCA is a rapid screening test that could be used to target patients for whom a more detailed neuropsychological assessment would be recommended.

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Predictors of objective cognitive impairment and subjective cognitive complaints in patients with Fabry disease

Scientific Reports ◽

10.1038/s41598-018-37320-0 ◽

2019 ◽

Vol 9 (1) ◽

Cited By ~ 3

Author(s):

Simon Körver ◽

Gert J. Geurtsen ◽

Carla E. M. Hollak ◽

Ivo N. van Schaik ◽

Maria G. F. Longo ◽

...

Keyword(s):

Cognitive Impairment ◽

Fabry Disease ◽

Cognitive Complaints ◽

Subjective Cognitive Complaints

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Comparison Between an Empirically Derived and a Standard Classification of Amnestic Mild Cognitive Impairment From a Sample Of Adults With Subjective Cognitive Complaints

Journal of Aging and Health ◽

10.1177/0898264315624908 ◽

2016 ◽

Vol 28 (6) ◽

pp. 1105-1115 ◽

Cited By ~ 2

Author(s):

María Campos-Magdaleno ◽

David Facal ◽

Onésimo Juncos-Rabadán ◽

Eduardo Picón ◽

Arturo Xosé Pereiro

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Amnestic Mild Cognitive Impairment ◽

Cognitive Complaints ◽

Standard Classification ◽

Subjective Cognitive Complaints

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Changes in visual memory in mild cognitive impairment: a longitudinal study with CANTAB

Psychological Medicine ◽

10.1017/s0033291720001142 ◽

2020 ◽

pp. 1-11 ◽

Cited By ~ 1

Author(s):

María Campos-Magdaleno ◽

David Leiva ◽

Arturo X. Pereiro ◽

Cristina Lojo-Seoane ◽

Sabela C. Mallo ◽

...

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Visual Memory ◽

Regression Models ◽

Cognitive Status ◽

Multinomial Regression ◽

Cognitive Complaints ◽

Spatial Span ◽

Evaluation Time ◽

Subjective Cognitive Complaints

Abstract Background Mild cognitive impairment (MCI), as a stage in the cognitive continuum between normal ageing and dementia, is mainly characterized by memory impairment. The aims of this study were to examine CANTAB measures of temporal changes of visual memory in MCI and to evaluate the usefulness of the baseline scores for predicting changes in cognitive status. Methods The study included 201 participants aged over 50 years with subjective cognitive complaints. Visual memory was assessed with four CANTAB tests [paired associates learning (PAL), delayed matching to sample (DMS), pattern recognition memory (PRM) and spatial span (SSP)] administered at baseline and on two further occasions, with a follow-up interval of 18–24 months. Participants were divided into three groups according to the change in their cognitive status: participants with subjective cognitive complaints who remained stable, MCI participants who remained stable (MCI-Stable) and MCI participants whose cognitive deterioration continued (MCI-Worsened). Linear mixed models were used to model longitudinal changes, with evaluation time as a fixed variable, and multinomial regression models were used to predict changes in cognitive status. Results Isolated significant effects were obtained for age and group with all CANTAB tests used. Interactions between evaluation time and group were identified in the PAL and DMS tests, indicating different temporal patterns depending on the changes in cognitive status. Regression models also indicated that CANTAB scores were good predictors of changes in cognitive status. Conclusions Decline in visual memory measured by PAL and DMS tests can successfully distinguish different types of MCI, and considered together PAL, DMS, PRM and SSP can predict changes in cognitive status.

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Subjective Memory Complaints and Conversion to Dementia in Patients with Subjective Cognitive Decline and Patients with Mild Cognitive Impairment

Zeitschrift für Neuropsychologie ◽

10.1024/1016-264x/a000175 ◽

2016 ◽

Vol 27 (2) ◽

pp. 85-93 ◽

Cited By ~ 3

Author(s):

Johann Lehrner ◽

Bettina Bodendorfer ◽

Claus Lamm ◽

Doris Moser ◽

Peter Dal-Bianco ◽

...

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Cognitive Decline ◽

Verbal Memory ◽

Clinical Sample ◽

Subjective Cognitive Decline ◽

Memory Testing ◽

Cognitive Complaints ◽

Subjective Memory ◽

Subjective Cognitive Complaints

Abstract. Background: Subjective cognitive complaints and their clinical significance are discussed controversially. Objectives: To determine the clinical validity of subjective cognitive complaints among subjects with subjective cognitive decline (SCD) and mild cognitive impairment (MCI). Design: Longitudinal study with one follow up examination at a University based out-patient memory clinic. Participants: A clinical sample of patietns with SCD and MCI (n = 141), aged 50 and older, who came to the memory outpatient clinic. Results: No significant differences between converters and non converters regarding subjective cognitive complaints were detected. MCI patients had a higher risk than the patients with SCD developing AD (OR = 7.3 [CI 0.9 to 61.2]. Verbal memory testing using the Verbal Selektive Reminding Test (VSRT) showed better diagnostic validity than subjective cognitive complaints using the Forgetfulness Assessment Inventory (FAI) in predicting conversion to dementia. Conclusion: Verbal memory testing was superior in predicting conversion to dementia compared to subjective cognitive complaints.

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What Do Cognitive Complaints in a Sample of Memory Clinic Outpatients Reflect?

GeroPsych ◽

10.1024/1662-9647/a000046 ◽

2011 ◽

Vol 24 (4) ◽

pp. 187-195 ◽

Cited By ~ 9

Author(s):

Anna Mascherek ◽

Daniel Zimprich ◽

Roland Rupprecht ◽

Frieder R. Lang

Keyword(s):

Cognitive Impairment ◽

Cognitive Functioning ◽

Cognitive Performance ◽

Semantic Fluency ◽

Regression Analyses ◽

Memory Clinic ◽

Cognitive Complaints ◽

Cognitive Measures ◽

Conflicting Evidence ◽

Subjective Cognitive Complaints

Conflicting evidence exists concerning the value of cognitive complaints in the course of assessing cognitive performance in individuals. The present study examines whether cognitive complaints are differentially related to cognitive functioning in groups with different diagnoses. 169 older outpatients (76 years on average) were divided into three groups and diagnosed with subjective cognitive complaints, mild cognitive impairment, or dementia. They were then administered a self-rating questionnaire on cognitive complaints, with semantic fluency and global cognitive functioning being assessed as cognitive measures. Multiple regression analyses revealed that, after controlling for depression, age, sex, and education, global cognitive functioning was not related to cognitive complaints. Semantic fluency was related to cognitive complaints depending on the group. Results suggest that cognitive complaints reflect, in part, actual cognitive performance.

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