Opportunities for Integrated Control of Neglected Tropical Diseases That Affect the Skin

2016 ◽  
Vol 32 (11) ◽  
pp. 843-854 ◽  
Author(s):  
Daniel Engelman ◽  
L. Claire Fuller ◽  
Anthony W. Solomon ◽  
James S. McCarthy ◽  
Roderick J. Hay ◽  
...  
Keyword(s):  
Neglected Tropical Diseases ◽  
Integrated Control ◽  
Tropical Diseases

scholarly journals Rapid mapping of schistosomiasis and other neglected tropical diseases in the context of integrated control programmes in Africa

Parasitology ◽  
2009 ◽  
Vol 136 (13) ◽  
pp. 1707-1718 ◽  
Author(s):  
S. BROOKER ◽  
N. B. KABATEREINE ◽  
J. O. GYAPONG ◽  
J. R. STOTHARD ◽  
J. UTZINGER
Keyword(s):  
High Risk ◽  
Neglected Tropical Diseases ◽  
Integrated Control ◽  
Sampling Technique ◽  
Epidemiological Data ◽  
Tropical Diseases ◽  
Survey Tool ◽  
Rapid Mapping ◽  
Effective Manner ◽  
Risk Communities

SUMMARYThere is growing interest and commitment to the control of schistosomiasis and other so-called neglected tropical diseases (NTDs). Resources for control are inevitably limited, necessitating assessment methods that can rapidly and accurately identify and map high-risk communities so that interventions can be targeted in a spatially-explicit and cost-effective manner. Here, we review progress made with (1) mapping schistosomiasis across Africa using available epidemiological data and, more recently, climate-based risk prediction; (2) the development and use of morbidity questionnaires for rapid identification of high-risk communities of urinary schistosomiasis; and (3) innovative sampling-based approaches for intestinal schistosomiasis, using the lot quality assurance sampling technique. Experiences are also presented for the rapid mapping of other NTDs, including onchocerciasis, loiasis and lymphatic filariasis. Future directions for an integrated rapid mapping approach targeting multiple NTDs simultaneously are outlined, including potential challenges in developing an integrated survey tool. The lessons from the mapping of human helminth infections may also be relevant for the rapid mapping of malaria as its control efforts are intensified.

scholarly journals The burden of neglected tropical diseases in Ethiopia, and opportunities for integrated control and elimination

2012 ◽  
Vol 5 (1) ◽  
Author(s):  
Kebede Deribe ◽  
Kadu Meribo ◽  
Teshome Gebre ◽  
Asrat Hailu ◽  
Ahmed Ali ◽  
...  
Keyword(s):  
Neglected Tropical Diseases ◽  
Integrated Control ◽  
Tropical Diseases

scholarly journals RESISTING CONTROL OF NEGLECTED TROPICAL DISEASES: DILEMMAS IN THE MASS TREATMENT OF SCHISTOSOMIASIS AND SOIL-TRANSMITTED HELMINTHS IN NORTH-WEST UGANDA

2008 ◽  
Vol 40 (2) ◽  
pp. 161-181 ◽  
Author(s):  
MELISSA PARKER ◽  
TIM ALLEN ◽  
JULIE HASTINGS
Keyword(s):  
Neglected Tropical Diseases ◽  
Integrated Control ◽  
Behavioural Change ◽  
Treatment Resistance ◽  
Tropical Diseases ◽  
Mass Treatment ◽  
North West ◽  
Soil Transmitted Helminths ◽  
Free Treatment ◽  
Effective Delivery

SummaryA strong case has recently been made by academics and policymakers to develop national programmes for the integrated control of Africa’s ‘neglected tropical diseases’. Uganda was the first country to develop a programme for the integrated control of two of these diseases: schistosomiasis and soil-transmitted helminths. This paper discusses social responses to the programme in Panyimur, north-west Uganda. It shows that adults are increasingly rejecting free treatment. Resistance is attributed to a subjective fear of side-effects; divergence between biomedical and local understandings of schistosomiasis/bilharzia; as well as inappropriate and inadequate health education. In addition, the current procedures for distributing drugs at a district level are problematic. Additional research was carried out in neighbouring areas to explore the generalizability of findings. Comparable problems have arisen. It is concluded that the national programme will not fulfil its stated objectives of establishing a local demand for mass treatment unless it can establish more effective delivery strategies and promote behavioural change in socially appropriate ways. To do so will require new approaches to social, economic and political aspects of distribution. There are reasons why populations infected with the ‘neglected tropical diseases’ are themselves neglected. Those reasons cannot just be wished away.

scholarly journals Organization of oversight for integrated control of neglected tropical diseases within Ministries of Health

2018 ◽  
Vol 12 (11) ◽  
pp. e0006929 ◽  
Author(s):  
Claire Standley ◽  
Matthew R. Boyce ◽  
Anna Klineberg ◽  
Gabrielle Essix ◽  
Rebecca Katz
Keyword(s):  
Neglected Tropical Diseases ◽  
Integrated Control ◽  
Tropical Diseases

scholarly journals Overcoming the Challenges of Drug Discovery for Neglected Tropical Diseases

2013 ◽  
Vol 19 (3) ◽  
pp. 335-343 ◽  
Author(s):  
Kelly L. Johnston ◽  
Louise Ford ◽  
Mark J. Taylor
Keyword(s):  
Drug Discovery ◽  
Neglected Tropical Diseases ◽  
Integrated Control ◽  
Development Program ◽  
Control Measures ◽  
World Health ◽  
Poor People ◽  
Tropical Diseases ◽  
Drug Discovery And Development ◽  
Health Organization

Neglected tropical diseases (NTDs) are a group of 17 diseases that typically affect poor people in tropical countries. Each has been neglected for decades in terms of funding, research, and policy, but the recent grouping of them into one unit, which can be targeted using integrated control measures, together with increased advocacy has helped to place them on the global health agenda. The World Health Organization has set ambitious goals to control or eliminate 10 NTDs by 2020 and launched a roadmap in January 2012 to guide this global plan. The result of the launch meeting, which brought together representatives from the pharmaceutical industry, donors, and politicians, was the London Declaration: a series of commitments to provide more drugs, research, and funds to achieve the 2020 goals. Drug discovery and development for these diseases are extremely challenging, and this article highlights these challenges in the context of the London Declaration, before focusing on an example of a drug discovery and development program for the NTDs onchocerciasis and lymphatic filariasis (the anti- Wolbachia consortium, A·WOL).

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