scholarly journals Prevalence, incidence, and natural history of HPV infection in adult women ages 24 to 45 participating in a vaccine trial

2020 ◽  
Vol 10 ◽  
pp. 100202
Author(s):  
Daron G. Ferris ◽  
Darron R. Brown ◽  
Anna R. Giuliano ◽  
Evan Myers ◽  
Elmar A. Joura ◽  
...  
Keyword(s):  
Natural History ◽  
Vaccine Trial ◽  
Hpv Infection ◽  
Adult Women ◽  
History Of

scholarly journals Human Papillomavirus and Genital Disease in Men: What We Have Learned from the HIM Study

2019 ◽  
Vol 63 (2) ◽  
pp. 109-117 ◽  
Author(s):  
Laura Sichero ◽  
Anna R. Giuliano ◽  
Luisa Lina Villa
Keyword(s):  
Human Papillomavirus ◽  
Natural History ◽  
The United States ◽  
Hpv Infection ◽  
Clinical Consequences ◽  
History Of ◽  
Crucial Information ◽  
Associated Risk Factors ◽  
The Relationship ◽  
Genital Disease

It is currently recognized that in addition to the major impact of human papillomavirus (HPV) infection in females, HPV causes considerable disease in men at the genitals, anal canal, and oropharynx. Specifically, genital HPV infections may progress to genital warts and penile carcinoma. Although studies concerning the natural history of HPV infections and associated neoplasias have mainly focused on women, during the last 2 decades considerable attention has been given in further understanding these infections in men. The HIM (HPV infection in men) Study, the only prospective multicenter study of male HPV natural history, consisted of a large prospective international cohort study in which men from Brazil, the United States, and Mexico were enrolled. The design and protocols of this study allowed unraveling crucial information regarding the relationship between HPV infection and clinical consequences in men, and associated risk factors at each of the anatomic sites where HPV is known to cause cancer in men.

scholarly journals Short-term natural history of high-risk human papillomavirus infection in mid-adult women sampled monthly

2015 ◽  
Vol 137 (10) ◽  
pp. 2432-2442 ◽  
Author(s):  
Tsung-chieh Jane Fu ◽  
Long Fu Xi ◽  
Ayaka Hulbert ◽  
James P. Hughes ◽  
Qinghua Feng ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
High Risk ◽  
Natural History ◽  
Adult Women ◽  
Short Term ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection ◽  
History Of

scholarly journals P1-229 Diet quality of male adult participants him study- Brazil (natural history of hpv infection in men): multicentric study

2011 ◽  
Vol 65 (Suppl 1) ◽  
pp. A130-A130
Author(s):  
J. Carlos ◽  
A. Previdelli ◽  
G. Bartira ◽  
M. L. Baggio ◽  
A. Giuliano ◽  
...  
Keyword(s):  
Natural History ◽  
Diet Quality ◽  
Hpv Infection ◽  
Male Adult ◽  
Multicentric Study ◽  
Adult Participants ◽  
History Of

scholarly journals Natural History of Polyomaviruses in Men: The HPV Infection in Men (HIM) Study

2014 ◽  
Vol 211 (9) ◽  
pp. 1437-1446 ◽  
Author(s):  
Shalaka S. Hampras ◽  
Anna R. Giuliano ◽  
Hui-Yi Lin ◽  
Kate J. Fisher ◽  
Martha E. Abrahamsen ◽  
...  
Keyword(s):  
Natural History ◽  
Hpv Infection ◽  
History Of

scholarly journals Natural History of Progression of HPV Infection to Cervical Lesion or Clearance: Analysis of the Control Arm of the Large, Randomised PATRICIA Study

PLoS ONE ◽  
2013 ◽  
Vol 8 (11) ◽  
pp. e79260 ◽  
Author(s):  
Unnop Jaisamrarn ◽  
Xavier Castellsagué ◽  
Suzanne M. Garland ◽  
Paulo Naud ◽  
Johanna Palmroth ◽  
...  
Keyword(s):  
Natural History ◽  
Hpv Infection ◽  
Cervical Lesion ◽  
History Of

scholarly journals Polymorphism in the promoter region of the Toll-like receptor 9 gene and cervical human papillomavirus infection

2013 ◽  
Vol 94 (8) ◽  
pp. 1858-1864 ◽  
Author(s):  
Lucas Boeno Oliveira ◽  
Karolina Louvanto ◽  
Agnihotram V. Ramanakumar ◽  
Eduardo L. Franco ◽  
Luisa L. Villa ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Natural History ◽  
Promoter Region ◽  
Pcr Amplification ◽  
Hpv Infection ◽  
Toll Like Receptor ◽  
Mediating Role ◽  
Papillomavirus Infection ◽  
Tlr9 Gene ◽  
History Of

Polymorphism in the Toll-like receptor (TLR) 9 gene has been shown to have a significant role in some diseases; however, little is known about its possible role in the natural history of human papillomavirus (HPV) infections. We investigated the association between a single-nucleotide polymorphism (SNP) (rs5743836) in the promoter region of TLR9 (T1237C) and type-specific HPV infections. Specimens were derived from a cohort of 2462 women enrolled in the Ludwig–McGill Cohort Study. We randomly selected 500 women who had a cervical HPV infection detected at least once during the study as cases. We defined two control groups: (i) a random sample of 300 women who always tested HPV negative, and (ii) a sample of 234 women who were always HPV negative but had a minimum of ten visits during the study. TLR9 genotyping was performed using bidirectional PCR amplification of specific alleles. Irrespective of group, the WT homozygous TLR9 genotype (TT) was the most common form, followed by the heterozygous (TC) and the mutant homozygous (CC) forms. There were no consistent associations between polymorphism and infection risk, either overall or by type or species. Likewise, there were no consistently significant associations between polymorphism and HPV clearance or persistence. We concluded that this polymorphism in the promoter region of TLR9 gene does not seem to have a mediating role in the natural history of the HPV infection.

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