The radioprotector ortho-phospho- L -tyrosine (pTyr) attenuates the side effects of fractionated irradiation in retinoblastoma mouse models but also decreases the local tumour control

2017 ◽  
Vol 124 (3) ◽  
pp. 462-467
Author(s):  
Alexander V. Tschulakow ◽  
Klaus Dittmann ◽  
Stephan M. Huber ◽  
Dominik Klumpp ◽  
Benjamin Stegen ◽  
...  
Keyword(s):  
Side Effects ◽  
Mouse Models ◽  
Fractionated Irradiation ◽  
Tumour Control ◽  
Local Tumour Control ◽  
Local Tumour

Simultaneous PLK1 inhibition improves local tumour control after fractionated irradiation

2013 ◽  
Vol 108 (3) ◽  
pp. 422-428 ◽  
Author(s):  
Mechthild Krause ◽  
Berit Kummer ◽  
Andre Deparade ◽  
Wolfgang Eicheler ◽  
Dorothee Pfitzmann ◽  
...  
Keyword(s):  
Fractionated Irradiation ◽  
Tumour Control ◽  
Local Tumour Control ◽  
Local Tumour

Radiobiological hypoxia, histological parameters of tumour microenvironment and local tumour control after fractionated irradiation

2010 ◽  
Vol 96 (1) ◽  
pp. 116-122 ◽  
Author(s):  
Ala Yaromina ◽  
Howard Thames ◽  
Xuanjing Zhou ◽  
Sandra Hering ◽  
Wolfgang Eicheler ◽  
...  
Keyword(s):  
Tumour Microenvironment ◽  
Fractionated Irradiation ◽  
Tumour Control ◽  
Local Tumour Control ◽  
Local Tumour

Combined treatment of the immunoconjugate bivatuzumab mertansine and fractionated irradiation improves local tumour control in vivo

2012 ◽  
Vol 102 (3) ◽  
pp. 444-449 ◽  
Author(s):  
Kristin Gurtner ◽  
Franziska Hessel ◽  
Wolfgang Eicheler ◽  
Annegret Dörfler ◽  
Daniel Zips ◽  
...  
Keyword(s):  
Combined Treatment ◽  
Fractionated Irradiation ◽  
Tumour Control ◽  
Local Tumour Control ◽  
Local Tumour

Nuklearmedizin trifft Strahlentherapie

2010 ◽  
Vol 49 (S 01) ◽  
pp. S11-S15
Author(s):  
C. Schütze ◽  
M. Krause ◽  
A. Yaromina ◽  
D. Zips ◽  
M. Baumann
Keyword(s):  
Nuclear Medicine ◽  
Radiation Oncology ◽  
External Beam Radiotherapy ◽  
Biological Knowledge ◽  
Important Research ◽  
Tumour Control ◽  
Research Areas ◽  
Normal Tissue Damage ◽  
Local Tumour Control ◽  
Local Tumour

SummaryRadiobiological and cell biological knowledge is increasingly used to further improve local tumour control or to reduce normal tissue damage after radiotherapy. Important research areas are evolving which need to be addressed jointly by nuclear medicine and radiation oncology. For this differences of the biological distribution of diagnostic and therapeutic nuclides compared with the more homogenous dose-distribution of external beam radiotherapy have to be taken into consideration. Examples for interdisciplinary biology-based cancer research in radiation oncology and nuclear medicine include bioimaging of radiobiological parameters characterizing radioresistance, bioimage-guided adaptive radiotherapy, and the combination of radiotherapy with molecular targeted drugs.

PO-1926 Enhanced local tumour control by combining proton radiation and immunotherapy

2021 ◽  
Vol 161 ◽  
pp. S1642
Author(s):  
M. Horsman ◽  
S. Nielsen ◽  
M. Sitarz ◽  
M. Høyer ◽  
B. Sørensen
Keyword(s):  
Proton Radiation ◽  
Tumour Control ◽  
Local Tumour Control ◽  
Local Tumour
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