Alveolar soft part sarcoma presenting metastatic hypermetabolic cervical lymph nodes on FDG PET/CT

2014 ◽  
Vol 33 (2) ◽  
pp. 118-119
Author(s):  
E.B. Erdogan ◽  
S. Asa ◽  
S. Yilmaz Aksoy ◽  
M. Halac
Keyword(s):  
Lymph Nodes ◽  
Fdg Pet ◽  
Soft Part ◽  
Alveolar Soft Part Sarcoma ◽  
Cervical Lymph Nodes ◽  
Pet Ct ◽  
Fdg Pet Ct

scholarly journals Development and validation of radiologic scores for guiding individualized induction chemotherapy in T3N1M0 nasopharyngeal carcinoma

2022 ◽  
Author(s):  
Shan-Shan Yang ◽  
Yi-Shan Wu ◽  
Ya-Jun Pang ◽  
Su-Ming Xiao ◽  
Bao-Yu Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
Nasopharyngeal Carcinoma ◽  
Lymph Nodes ◽  
Fdg Pet ◽  
Cervical Lymph Nodes ◽  
Pet Ct ◽  
Risk Patients ◽  
Fdg Pet Ct ◽  
Ct And Mri

Abstract Objectives We aimed to develop and validate radiologic scores from [18F]FDG PET/CT and MRI to guide individualized induction chemotherapy (IC) for patients with T3N1M0 nasopharyngeal carcinoma (NPC). Methods A total of 542 T3N1M0 patients who underwent pretreatment [18F]FDG PET/CT and MRI were enrolled in the training cohort. A total of 174 patients underwent biopsy of one or more cervical lymph nodes. Failure-free survival (FFS) was the primary endpoint. The radiologic score, which was calculated according to the number of risk factors from the multivariate model, was used for risk stratification. The survival difference of patients undergoing concurrent chemoradiotherapy (CCRT) with or without IC was then compared in risk-stratified subgroups. Another cohort from our prospective clinical trial (N = 353, NCT03003182) was applied for validation. Results The sensitivity of [18F]FDG PET/CT was better than that of MRI (97.7% vs. 87.1%, p < 0.001) for diagnosing histologically proven metastatic cervical lymph nodes. Radiologic lymph node characteristics were independent risk factors for FFS (all p < 0.05). High-risk patients (n = 329) stratified by radiologic score benefited from IC (5-year FFS: IC + CCRT 83.5% vs. CCRT 70.5%; p = 0.0044), while low-risk patients (n = 213) did not. These results were verified again in the validation cohort. Conclusions T3N1M0 patients were accurately staged by both [18F]FDG PET/CT and MRI. The radiologic score can correctly identify high-risk patients who can gain additional survival benefit from IC and it can be used to guide individualized treatment of T3N1M0 NPC. Key Points • [18F]FDG PET/CT was more accurate than MRI in diagnosing histologically proven cervical lymph nodes. • Radiologic lymph node characteristics were reliable independent risk factors for FFS in T3N1M0 nasopharyngeal carcinoma patients. • High-risk patients identified by the radiologic score based on [18F]FDG PET/CT and MRI could benefit from the addition of induction chemotherapy.

scholarly journals Hypermetabolic abdominal and cervical lymph nodes mimicking Hodgkin lymphoma relapse on FDG PET/CT after adenovirus-vectored COVID-19 vaccine

2021 ◽  
pp. 1-4
Author(s):  
Elena Landete ◽  
Isabel Gómez-Fernández ◽  
Isabel González-Gascón-y-Marín ◽  
Carmen Durán-Barquero ◽  
Juan Churruca ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Hodgkin Lymphoma ◽  
Fdg Pet ◽  
Cervical Lymph Nodes ◽  
Pet Ct ◽  
Fdg Pet Ct

CT, MRI, and FDG PET/CT in a Patient With Alveolar Soft Part Sarcoma

2014 ◽  
Vol 39 (3) ◽  
pp. 265-267 ◽  
Author(s):  
Aisheng Dong ◽  
Yang Wang ◽  
Chao Cheng ◽  
Changjing Zuo
Keyword(s):  
Fdg Pet ◽  
Soft Part ◽  
Alveolar Soft Part Sarcoma ◽  
Pet Ct ◽  
Fdg Pet Ct

scholarly journals Head-to-Head Comparison of Neck 18F-FDG PET/MR and PET/CT in the Diagnosis of Differentiated Thyroid Carcinoma Patients after Comprehensive Treatment

Cancers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 3436
Author(s):  
Yangmeihui Song ◽  
Fang Liu ◽  
Weiwei Ruan ◽  
Fan Hu ◽  
Muhsin H. Younis ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Fdg Pet ◽  
Differentiated Thyroid Carcinoma ◽  
Comprehensive Treatment ◽  
Cervical Lymph Nodes ◽  
Detection Rates ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

We explored the clinical value of 18F-FDG PET/MR in a head-to-head comparison with PET/CT in loco-regional recurrent and metastatic cervical lymph nodes of differentiated thyroid carcinoma (DTC) patients after comprehensive treatment. 18F-FDG PET/CT and neck PET/MR scans that were performed in DTC patients with suspected recurrence or cervical lymph node metastasis after comprehensive treatment were retrospectively analyzed. Detection rates, diagnostic efficacy, image conspicuity, and measured parameters were compared between 18F-FDG PET/CT and PET/MR. The gold standard was histopathological diagnosis or clinical and imaging follow-up results for more than 6 months. Among the 37 patients enrolled, no suspicious signs of tumor were found in 10 patients, 24 patients had lymph node metastasis, and 3 patients had both recurrence and lymph node metastases. A total of 130 lesions were analyzed, including 3 malignant and 6 benign thyroid nodules, as well as 74 malignant and 47 benign cervical lymph nodes. Compared with PET/CT, PET/MR presented better detection rates (91.5% vs. 80.8%), image conspicuity (2.74 ± 0.60 vs. 1.9 ± 0.50, p < 0.001, especially in complex level II), and sensitivity (80.5% vs. 61.0%). SUVmax differed in benign and malignant lymph nodes in both imaging modalities (p < 0.05). For the same lesion, the SUVmax, SUVmean, and diameters measured by PET/MR and PET/CT were consistent and had significant correlation. In conclusion, compared with 18F-FDG PET/CT, PET/MR was more accurate in determining recurrent and metastatic lesions, both from a patient-based and from a lesion-based perspective. Adding local PET/MR after whole-body PET/CT may be recommended to provide more precise diagnostic information and scope of surgical resection without additional ionizing radiation. Further scaling-up prospective studies and economic benefit analysis are expected.

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