scholarly journals Radiosensitizing properties of magnetic hyperthermia mediated by superparamagnetic iron oxide nanoparticles (SPIONs) on human cutaneous melanoma cell lines

2019 ◽  
Vol 24 (2) ◽  
pp. 152-157 ◽  
Author(s):  
Jakub Dalibor Rybka
2014 ◽  
Vol 802 ◽  
pp. 535-539 ◽  
Author(s):  
Fernanda A. Sampaio da Silva ◽  
Edwin E.G. Rojas ◽  
Sérgio Romero ◽  
Marcos Flávio de Campos

Nowadays, superparamagnetic iron oxide nanoparticles are an important tool for cancer treatment, such as magnetic hyperthermia. The goal is heating diseased tissue and then tumor cells are destroyed. Magnetic nanoparticles are promising mainly because they have specific ability to reduce side effects. However, forin vivoapplications, nanoparticles need to be coated by a biocompatible material. In this work, nanoparticles are coated by PEG (biocompatible polymer). Samples were produced by coprecipitation process. Information about particle size, magnetic properties and crystallinity were obtained.


2020 ◽  
Vol 10 (20) ◽  
pp. 7322 ◽  
Author(s):  
Sebastjan Nemec ◽  
Slavko Kralj ◽  
Claire Wilhelm ◽  
Ali Abou-Hassan ◽  
Marie-Pierre Rols ◽  
...  

Photothermal therapy is gathering momentum. In order to assess the effects of the encapsulation of individual or clustered superparamagnetic iron oxide nanoparticles (SPIONs) on nanoparticle light-to-heat conversion, we designed and tested individual and clustered SPIONs encapsulated within a silica shell. Our study compared both photothermia and magnetic hyperthermia, and it involved individual SPIONs as well as silica-encapsulated individual and clustered SPIONs. While, as expected, SPION clustering reduced heat generation in magnetic hyperthermia, the silica shell improved SPION heating in photothermia.


2019 ◽  
Vol 48 (12) ◽  
pp. 3883-3892 ◽  
Author(s):  
Santiago Sánchez-Cabezas ◽  
Roberto Montes-Robles ◽  
Juan Gallo ◽  
Félix Sancenón ◽  
Ramón Martínez-Máñez

Highly-stable ultrasmall superparamagnetic iron oxide nanoparticles (USPIONs) show great potential for the development of theranostic nanodevices.


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