Genomic and pathogenic analysis of a Muscovy duck parvovirus strain causing short beak and dwarfism syndrome without tongue protrusion

Abstract Derzsy’s disease and Muscovy duck parvovirus disease have become common diseases in waterfowl culture in the world and their potential to cause harm has risen. The causative agents are goose parvovirus (GPV) and Muscovy duck parvovirus (MDPV), which can provoke similar clinical symptoms and high mortality and morbidity rates. In recent years, duck short beak and dwarfism syndrome has been prevalent in the Cherry Valley duck population in eastern China. It is characterised by the physical signs for which it is named. Although the mortality rate is low, it causes stunting and weight loss, which have caused serious economic losses to the waterfowl industry. The virus that causes this disease was named novel goose parvovirus (NGPV). This article summarises the latest research on the genetic relationships of the three parvoviruses, and reviews the aetiology, epidemiology, and necropsy characteristics in infected ducks, in order to facilitate further study.

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Genetic characterization and phylogenetic analysis of Novel Duck-Origin Goose Parvovirus in Anhui Province, Eastern China

10.21203/rs.3.rs-202531/v1 ◽

2021 ◽

Author(s):

Yong Wang ◽

Jianfei Sun ◽

Da Zhang ◽

Xu Guo ◽

Wenhao Shen ◽

...

Keyword(s):

Phylogenetic Analysis ◽

Genome Sequencing ◽

Phylogenetic Trees ◽

Genetic Characterization ◽

Eastern China ◽

Anhui Province ◽

Muscovy Duck ◽

Goose Parvovirus ◽

Short Beak ◽

Muscovy Duck Parvovirus

Abstract Recently, a novel duck-origin goose parvovirus (N-GPV) was reported to cause short beak and dwarfism syndrome in ducks. In this study, we performed complete genome sequencing and analyzed three different duck-derived parvoviruses that infected different breeds of ducks. Phylogenetic trees based on gene sequences indicated that they were classical goose parvovirus (C-GPV), Muscovy duck parvovirus (MDPV), and N-GPV, respectively. Furthermore, potential recombination events were found. These results improve our understanding of the diversity of duck-derived parvoviruses in the Anhui province, eastern China, and provide a reference for the prevention of associated diseases.

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Expression of Muscovy Duck Parvovirus Capsid Proteins (VP2 and VP3) in a Baculovirus Expression System and Demonstration of Immunity Induced by the Recombinant Proteins

Journal of General Virology ◽

10.1099/0022-1317-77-9-2159 ◽

1996 ◽

Vol 77 (9) ◽

pp. 2159-2163 ◽

Cited By ~ 38

Author(s):

G. Le Gall-Recule ◽

V. Jestin ◽

P. Chagnaud ◽

P. Blanchard ◽

A. Jestin

Keyword(s):

Recombinant Proteins ◽

Expression System ◽

Baculovirus Expression System ◽

Capsid Proteins ◽

Muscovy Duck ◽

Baculovirus Expression ◽

Muscovy Duck Parvovirus

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Selection of an aptamer against Muscovy duck parvovirus for highly sensitive rapid visual detection by label-free aptasensor

Talanta ◽

10.1016/j.talanta.2017.08.037 ◽

2018 ◽

Vol 176 ◽

pp. 214-220 ◽

Cited By ~ 10

Author(s):

Taofeng Lu ◽

Qin Ma ◽

Wenzhuo Yan ◽

Yuanzhi Wang ◽

Yuanyuan Zhang ◽

...

Keyword(s):

Visual Detection ◽

Muscovy Duck ◽

Label Free ◽

Highly Sensitive ◽

Muscovy Duck Parvovirus ◽

Selection Of

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Transfection of embryonated Muscovy duck eggs with a recombinant plasmid is suitable for rescue of infectious Muscovy duck parvovirus

Archives of Virology ◽

10.1007/s00705-017-3541-8 ◽

2017 ◽

Vol 162 (12) ◽

pp. 3869-3874

Author(s):

Jianye Wang ◽

Yu Huang ◽

Jueyi Ling ◽

Zhixiang Wang ◽

Guoqiang Zhu

Keyword(s):

Recombinant Plasmid ◽

Muscovy Duck ◽

Muscovy Duck Parvovirus

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Sole recombinant Muscovy duck parvovirus infection in Muscovy ducklings can form characteristic intestinal embolism

Veterinary Microbiology ◽

10.1016/j.vetmic.2020.108590 ◽

2020 ◽

Vol 242 ◽

pp. 108590 ◽

Cited By ~ 1

Author(s):

Jianye Wang ◽

Qingling Mi ◽

Zhixian Wang ◽

Jingyu Jia ◽

Yonglin Li ◽

...

Keyword(s):

Muscovy Duck ◽

Muscovy Duck Parvovirus

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Detection of Novel Goose Parvovirus Disease Associated with Short Beak and Dwarfism Syndrome in Commercial Ducks

Animals ◽

10.3390/ani10101833 ◽

2020 ◽

Vol 10 (10) ◽

pp. 1833 ◽

Cited By ~ 1

Author(s):

Mohamed A. Soliman ◽

Ahmed M. Erfan ◽

Mohamed Samy ◽

Osama Mahana ◽

Soad A. Nasef

Keyword(s):

First Record ◽

Pekin Duck ◽

Economic Losses ◽

Morbidity Rate ◽

Muscovy Duck ◽

Performance Isolation ◽

Retarded Growth ◽

Goose Parvovirus ◽

Low Performance ◽

Short Beak

Derzsy’s disease causes disastrous losses in domestic waterfowl farms. A genetically variant strain of Muscovy duck parvovirus (MDPV) and goose parvovirus (GPV) was named novel goose parvovirus (NGPV), which causes characteristic syndrome in young ducklings. The syndrome was clinically characterized by deformity in beaks and retarded growth, called short beaks and dwarfism syndrome (SBDS). Ten mule and pekin duck farms were investigated for parvovirus in three Egyptian provinces. Despite low recorded mortality rate (20%), morbidity rate was high (70%), but the economic losses were remarkable as a result of retarded growth and low performance. Isolation of NGPV was successful on primary cell culture of embryonated duck liver cells with a clear cytopathic effect. Partial gene sequence of the VP1 gene showed high amino acids identity among isolated strains and close identity with Chinese strains of NGPV, and low identity with classic GPV and MDPV strains. To the best of our knowledge, this can be considered the first record of NGPV infections in Egypt.

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