Highly sensitive determination of diclofenac based on resin beads and a novel polyclonal antibody by using flow injection chemiluminescence competitive immunoassay

2018 ◽  
Vol 191 ◽  
pp. 1-7 ◽  
Author(s):  
Jing Shi ◽  
Mingxia Xu ◽  
Qinghui Tang ◽  
Kang Zhao ◽  
Anping Deng ◽  
...  
Keyword(s):  
Polyclonal Antibody ◽  
Flow Injection ◽  
Competitive Immunoassay ◽  
Resin Beads ◽  
Highly Sensitive ◽  
Sensitive Determination ◽  
Flow Injection Chemiluminescence

Flow injection chemiluminescence immunoassay based on resin beads, enzymatic amplification and a novel monoclonal antibody for determination of Hg2+

The Analyst ◽  
2015 ◽  
Vol 140 (18) ◽  
pp. 6373-6378 ◽  
Author(s):  
Mingxia Xu ◽  
Mengting Chen ◽  
Tiantian Dong ◽  
Kang Zhao ◽  
Anping Deng ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Flow Injection ◽  
Specific Monoclonal Antibody ◽  
Chemiluminescence Detection ◽  
Competitive Immunoassay ◽  
Chemiluminescence Immunoassay ◽  
Enzymatic Amplification ◽  
Resin Beads ◽  
Flow Injection Chemiluminescence

A convenient competitive immunoassay of Hg2+ using carboxylic resin beads, specific monoclonal antibody and enzymatic amplification is proposed with flow injection chemiluminescence detection.

Sensitive determination of synephrine by flow-injection chemiluminescence

Luminescence ◽  
2006 ◽  
Vol 21 (1) ◽  
pp. 43-48 ◽  
Author(s):  
Qian Li ◽  
Chengzhi Huang ◽  
Yuming Huang
Keyword(s):  
Flow Injection ◽  
Sensitive Determination ◽  
Flow Injection Chemiluminescence

Determination of risperidone at picogram level in human urine by luminol—H2O2 chemiluminescence

2006 ◽  
Vol 60 (4) ◽  
Author(s):  
X. Xie ◽  
X. Shao ◽  
Z. Song
Keyword(s):  
Flow Injection ◽  
Human Urine ◽  
High Sensitivity ◽  
Chemiluminescence Method ◽  
Synergistic Enhancement ◽  
Relative Standard ◽  
Sensitive Determination ◽  
Flow Injection Chemiluminescence ◽  
Simple Flow

AbstractA simple flow-injection chemiluminescence method with synergistic enhancement has been investigated for the rapid and sensitive determination of antipsychotic risperidone. The synergistic action was significant in the chemiluminescence system of luminol—hydrogen peroxide with risperidone as an enhancer. The increased chemiluminescence intensity was correlated with risperidone concentration within the range from 10 pg mL−1 to 1.0 ng mL−1 with relative standard deviations lower than 5.0 % and the detection limit of 4 pg mL−1. At a flow rate of 2.0 mL min−1, the flow-injection chemiluminescence method exhibited both a high sensitivity and excellent selectivity giving a throughput of 120 times per hour. The proposed method was successfully applied to determine the risperidone content in human urine without any pretreatment. It was found that the excretive amounts of risperidone reached their maximum after taking 2.0 mg of risperidone for 1 h, with a total excretive ratio of 17.37 % in 8.5 h.

scholarly journals Determination of Phenolic Sympathomimetic Drugs in Pharmaceutical Samples and Biological Fluids by Flow-Injection Chemiluminescence

2000 ◽  
Vol 83 (6) ◽  
pp. 1299-1305 ◽  
Author(s):  
Fatma A Aly ◽  
Salma A Al-Tamimi ◽  
Abdulrahman A Alwarthan
Keyword(s):  
Formic Acid ◽  
Flow Injection ◽  
Reaction Pathway ◽  
Biological Fluids ◽  
Dosage Forms ◽  
Pharmaceutical Samples ◽  
Sympathomimetic Drugs ◽  
Highly Sensitive ◽  
Flow Injection Chemiluminescence

Abstract A rapid and highly sensitive flow-injection chemiluminometric method was developed for determination of 3 sympathomimetic drugs, namely, etilefrine hydrochloride, isoxsuprine hydrochloride, and prenalterol hydrochloride. The method is based on chemiluminescence induced by oxidation of drugs with acidified potassium permanganate in the presence of formic acid as a carrier. The calibration graphs were linear over the concentration ranges 0.2–9, 0.2–12.5, and 0.025–1.25 μg/mL for the 3 compounds, respectively. The method was applied successfully in determining the drugs in dosage forms and in biological fluids. A proposal for the reaction pathway is suggested.

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