scholarly journals Corrigendum to “Rational design of a fluorescent probe for the detection of LAP and its application in drug-induced liver injury” [Spectrochim. Acta Part A: Mol. Biomol. Spectrosc. 251 (2021) 119362]

2021 ◽  
Vol 261 ◽  
pp. 120027
Author(s):  
Tao Liu ◽  
Manman Tian ◽  
Jiayue Wang ◽  
Xiangge Tian ◽  
Jihong Liu ◽  
...  
Keyword(s):  
Liver Injury ◽  
Fluorescent Probe ◽  
Rational Design ◽  
Drug Induced ◽  
Drug Induced Liver Injury

A hepatocyte-targeting near-infrared ratiometric fluorescent probe for monitoring peroxynitrite during drug-induced hepatotoxicity and its remediation

2019 ◽  
Vol 55 (95) ◽  
pp. 14307-14310 ◽  
Author(s):  
Wen-Li Jiang ◽  
Yongfei Li ◽  
Wen-Xin Wang ◽  
Yi-Ting Zhao ◽  
Junjie Fei ◽  
...  
Keyword(s):  
Liver Injury ◽  
Fluorescent Probe ◽  
Near Infrared ◽  
Living Cells ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Ratiometric Fluorescent Probe

A novel hepatocyte-targeting near-infrared ratiometric fluorescent probe named Gal-NIR is developed for detecting ONOO−. The probe can target the hepatocyte and assess drug-induced liver injury and its remediation in living cells and mice.

Efficient Two-Photon Fluorescent Probe for Glutathione S-Transferase Detection and Imaging in Drug-Induced Liver Injury Sample

2017 ◽  
Vol 89 (15) ◽  
pp. 8097-8103 ◽  
Author(s):  
Jing Zhang ◽  
Zhen Jin ◽  
Xiao-Xiao Hu ◽  
Hong-Min Meng ◽  
Jin Li ◽  
...  
Keyword(s):  
Liver Injury ◽  
Fluorescent Probe ◽  
Glutathione S Transferase ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Two Photon

scholarly journals Fluorescent Probe for the Imaging of Superoxide and Peroxynitrite during Drug-induced Liver Injury

2021 ◽  
Author(s):  
Luling Wu ◽  
Jihong Liu ◽  
Xue Tian ◽  
Robin Rupert Groleau ◽  
Steven Bull ◽  
...  
Keyword(s):  
Liver Disease ◽  
Liver Injury ◽  
Fluorescent Probe ◽  
Molecular Probe ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Fatal Liver

Drug-induced liver injury (DILI) is an important cause of potentially fatal liver disease. Herein, we report the development of a molecular probe (LW−OTf) for the detection and imaging of two...

scholarly journals In vivo imaging of leucine aminopeptidase activity in drug-induced liver injury and liver cancer via a near-infrared fluorescent probe

2017 ◽  
Vol 8 (5) ◽  
pp. 3479-3483 ◽  
Author(s):  
Xinyuan He ◽  
Lihong Li ◽  
Yu Fang ◽  
Wen Shi ◽  
Xiaohua Li ◽  
...  
Keyword(s):  
Liver Injury ◽  
Fluorescent Probe ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Leucine Aminopeptidase ◽  
Aminopeptidase Activity ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
First Time

The upregulation of leucine aminopeptidase in hepatopathy models is imaged in vivo for the first time with a near-infrared fluorescent probe.

Evaluating Drug-Induced Liver Injury and Its Remission via Discrimination and Imaging of HClO and H2S with a Two-Photon Fluorescent Probe

2018 ◽  
Vol 90 (12) ◽  
pp. 7510-7516 ◽  
Author(s):  
Xiaoyun Jiao ◽  
Yongsheng Xiao ◽  
Yong Li ◽  
Muwen Liang ◽  
Xilei Xie ◽  
...  
Keyword(s):  
Liver Injury ◽  
Fluorescent Probe ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Two Photon

Leberschaden unter oraler Antikoagulation, Statin- und ACE-Hemmertherapie

Praxis ◽  
2010 ◽  
Vol 99 (21) ◽  
pp. 1259-1265 ◽  
Author(s):  
Bruggisser ◽  
Terraciano ◽  
Rätz Bravo ◽  
Haschke
Keyword(s):  
Liver Injury ◽  
Wird Eine ◽  
Drug Induced ◽  
Drug Induced Liver Injury

Ein 71-jähriger Patient stellt sich mit Epistaxis und ikterischen Skleren auf der Notfallstation vor. Der Patient steht unter einer Therapie mit Phenprocoumon, Atorvastatin und Perindopril. Anamnestisch besteht ein langjähriger Alkoholabusus. Laborchemisch werden massiv erhöhte Leberwerte (ALAT, Bilirubin) gesehen. Der INR ist unter oraler Antikoagulation und bei akuter Leberinsuffizienz >12. Die weiterführenden Abklärungen schliessen eine Virushepatitis und eine Autoimmunhepatitis aus. Nachdem eine Leberbiopsie durchgeführt werden kann, wird eine medikamentös-toxische Hepatitis, ausgelöst durch die Komedikation von Atorvastatin, Phenprocoumon und Perindopril bei durch Alkohol bereits vorgeschädigter Leber diagnostiziert. Epidemiologie, Pathophysiologie und Klink der medikamentös induzierten Leberschäden (drug induced liver injury, DILI), speziell von Coumarinen, Statinen und ACE-Hemmern werden im Anschluss an den Fallbericht diskutiert.

Drug-induced liver injury network (DILIN)

Hepatology ◽  
2004 ◽  
Vol 40 (4) ◽  
pp. 773-773 ◽  
Author(s):  
Jay H. Hoofnagle
Keyword(s):  
Liver Injury ◽  
Drug Induced ◽  
Drug Induced Liver Injury
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