Efficient Two-Photon Fluorescent Probe for Glutathione S-Transferase Detection and Imaging in Drug-Induced Liver Injury Sample

2017 ◽  
Vol 89 (15) ◽  
pp. 8097-8103 ◽  
Author(s):  
Jing Zhang ◽  
Zhen Jin ◽  
Xiao-Xiao Hu ◽  
Hong-Min Meng ◽  
Jin Li ◽  
...  
Keyword(s):  
Liver Injury ◽  
Fluorescent Probe ◽  
Glutathione S Transferase ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Two Photon

Evaluating Drug-Induced Liver Injury and Its Remission via Discrimination and Imaging of HClO and H2S with a Two-Photon Fluorescent Probe

2018 ◽  
Vol 90 (12) ◽  
pp. 7510-7516 ◽  
Author(s):  
Xiaoyun Jiao ◽  
Yongsheng Xiao ◽  
Yong Li ◽  
Muwen Liang ◽  
Xilei Xie ◽  
...  
Keyword(s):  
Liver Injury ◽  
Fluorescent Probe ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Two Photon

Glutathione S-transferase M1 and T1 null genotypes increase susceptibility to drug-induced liver injury

Hepatology ◽  
2009 ◽  
Vol 49 (5) ◽  
pp. 1777-1777 ◽  
Author(s):  
Virginia Leiro Fernández ◽  
Alberto Fernández-Villar ◽  
Rafael Vázquez Gallardo ◽  
Diana Valverde Pérez
Keyword(s):  
Liver Injury ◽  
Glutathione S Transferase ◽  
Drug Induced ◽  
Drug Induced Liver Injury

A hepatocyte-targeting near-infrared ratiometric fluorescent probe for monitoring peroxynitrite during drug-induced hepatotoxicity and its remediation

2019 ◽  
Vol 55 (95) ◽  
pp. 14307-14310 ◽  
Author(s):  
Wen-Li Jiang ◽  
Yongfei Li ◽  
Wen-Xin Wang ◽  
Yi-Ting Zhao ◽  
Junjie Fei ◽  
...  
Keyword(s):  
Liver Injury ◽  
Fluorescent Probe ◽  
Near Infrared ◽  
Living Cells ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Ratiometric Fluorescent Probe

A novel hepatocyte-targeting near-infrared ratiometric fluorescent probe named Gal-NIR is developed for detecting ONOO−. The probe can target the hepatocyte and assess drug-induced liver injury and its remediation in living cells and mice.

A two-photon fluorescent sensor revealing drug-induced liver injury via tracking γ-glutamyltranspeptidase (GGT) level in vivo

Biomaterials ◽  
2016 ◽  
Vol 80 ◽  
pp. 46-56 ◽  
Author(s):  
Peisheng Zhang ◽  
Xiao-fang Jiang ◽  
Xuezheng Nie ◽  
Yong Huang ◽  
Fang Zeng ◽  
...  
Keyword(s):  
Liver Injury ◽  
Fluorescent Sensor ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Two Photon

scholarly journals Fluorescent Probe for the Imaging of Superoxide and Peroxynitrite during Drug-induced Liver Injury

2021 ◽  
Author(s):  
Luling Wu ◽  
Jihong Liu ◽  
Xue Tian ◽  
Robin Rupert Groleau ◽  
Steven Bull ◽  
...  
Keyword(s):  
Liver Disease ◽  
Liver Injury ◽  
Fluorescent Probe ◽  
Molecular Probe ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Fatal Liver

Drug-induced liver injury (DILI) is an important cause of potentially fatal liver disease. Herein, we report the development of a molecular probe (LW−OTf) for the detection and imaging of two...

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